Standout Papers
Citation Impact
Citing Papers
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
2001 StandoutScienceNobel
NUP145 encodes a novel yeast glycine-leucine-phenylalanine-glycine (GLFG) nucleoporin required for nuclear envelope structure.
1994 StandoutNobel
S. cerevisiae α pheromone receptors activate a novel signal transduction pathway for mating partner discrimination
1991 StandoutNobel
Chapter 11 Antigen Localization in Fission Yeast
1993
Cell wall integrity modulates RHO1 activity via the exchange factor ROM2
1998
The Essential Yeast Nucleoporin NUP159 Is Located on the Cytoplasmic Side of the Nuclear Pore Complex and Serves in Karyopherin-mediated Binding of Transport Substrate
1995 StandoutNobel
Higher order structure is present in the yeast nucleus: autoantibody probes demonstrate that the nucleolus lies opposite the spindle pole body
1989
The Yeast Clathrin Adaptor Protein Complex 1 Is Required for the Efficient Retention of a Subset of Late Golgi Membrane Proteins
2002 StandoutNobel
A novel protein modification pathway related to the ubiquitin system
1998
Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1
1991
KAR2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene
1989
A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains
1992 Nature
Chapter 8: GFP Fusion Proteins as Probes for Cytology in Fission Yeast
1998
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1999 StandoutNatureNobel
A Distinct Nuclear Import Pathway Used by Ribosomal Proteins
1997 StandoutNobel
The von Hippel–Lindau tumor suppressor protein
2001 StandoutNobel
Cell cycle control of morphogenesis in budding yeast
1995
Assembly and functions of the spindle pole body in budding yeast
1993
Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis
1998
Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes
1995 StandoutNobel
Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis
1998
F-Box Proteins Are Receptors that Recruit Phosphorylated Substrates to the SCF Ubiquitin-Ligase Complex
1997
Microtubule-Microfilament Synergy in the Cytoskeleton
1997
Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
1995 Standout
Profilin as a potential mediator of membrane-cytoskeleton communication
1993
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
The von Hippel-Lindau Tumor Suppressor Protein Is Required for Proper Assembly of an Extracellular Fibronectin Matrix
1998 StandoutNobel
The Nuclear Envelope of the Yeast Saccharomyces cerevisiae
1992
Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus
1999 Nature
Discovering the poles in yeast
1998 StandoutNobel
Exit from Mitosis Is Triggered by Tem1-Dependent Release of the Protein Phosphatase Cdc14 from Nucleolar RENT Complex
1999
SNAP receptors implicated in vesicle targeting and fusion
1993 StandoutNatureNobel
Cell polarity in yeast
1994
A new yeast gene with a myosin-like heptad repeat structure
1993
Kinesin-related proteins required for structural integrity of the mitotic spindle
1992
Selection of polarized growth sites in yeast
1996
The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases
1989
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
1992 Standout
The NUP1 gene encodes an essential component of the yeast nuclear pore complex
1990
S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
1991
Isolation and characterization of conditional-lethal mutations in the TUB1 alpha-tubulin gene of the yeast Saccharomyces cerevisiae.
1988
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
1998 Standout
The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery
1988
Budding and cell polarity in Saccharomyces cerevisiae
1991
A new NEDD8-ligating system for cullin-4A
1998
Modification of yeast Cdc53p by the ubiquitin-related protein Rub1p affects function of the SCFCdc4 complex
1998
Origins of Cell Polarity
1996
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
1994 Standout
Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast.
1993
Cooperative interaction of S. pombe proteins required for mating and morphogenesis
1994
Unlinked noncomplementation: isolation of new conditional-lethal mutations in each of the tubulin genes of Saccharomyces cerevisiae.
1988
Effects of the myosin inhibitor 2,3-butanedione monoxime on the physiology of fission yeast
1998
A homologue of the ras-related CDC42 gene from Schizosaccharomyces pombe
1992
Global analysis of protein localization in budding yeast
2003 StandoutNature
KAR3, a kinesin-related gene required for yeast nuclear fusion
1990
Interactions among Proteins Involved in Bud-site Selection and Bud-site Assembly in Saccharomyces cerevisiae
1995
Establishment of Cell Polarity in Yeast
1995
Cell polarity and morphogenesis in Saccharomyces cerevisiae
1992
SH3 — an abundant protein domain in search of a function
1992
Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint.
1993 StandoutNobel
Mitotic spindle pulls but fails to separate chromosomes in type II DNA topoisomerase mutants: uncoordinated mitosis
1986
CLIP170-like tip1p Spatially Organizes Microtubular Dynamics in Fission Yeast
2000 StandoutNobel
A ubiquitin-like system mediates protein lipidation
2000 StandoutNatureNobel
The myosin ATPase inhibitor 2,3-butanedione-2-monoxime (BDM) inhibits tip growth and cytokinesis in the fission yeast,Schizosaccharomyces pombe
1998
tea1 and the Microtubular Cytoskeleton Are Important for Generating Global Spatial Order within the Fission Yeast Cell
1997 StandoutNobel
Suppressors of yeast actin mutations.
1989
Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway
1991
Identification and functional analysis of the nuclear localization signals of ribosomal protein L25 from Saccharomyces cerevisiae
1991
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Structure of the yeast endoplasmic reticulum: Localization of ER proteins using immunofluorescence and immunoelectron microscopy
1991
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Structure, biosynthesis, and localization of dipeptidyl aminopeptidase B, an integral membrane glycoprotein of the yeast vacuole.
1989
Proteins Connecting the Nuclear Pore Complex with the Nuclear Interior
1999 StandoutNobel
Targeting of Chitin Synthase 3 to Polarized Growth Sites in Yeast Requires Chs5p and Myo2p
1997
CELL POLARITY AND MORPHOGENESIS IN BUDDING YEAST
1998
Temperature-sensitive yeast mutants defective in mitochondrial inheritance.
1990
The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesicles.
1991
Characterization of the chitin biosynthesis process as a compensatory mechanism in the fks1 mutant of Saccharomyces cerevisiae
2000
Pheromone Response in Yeast: Association of Bem1p with Proteins of the MAP Kinase Cascade and Actin
1995 Science
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p.
1995 StandoutNobel
Fission yeast cell morphogenesis: identification of new genes and analysis of their role during the cell cycle.
1995 StandoutNobel
Polarization of cell growth in yeast: I. Establishment and maintenance of polarity states
2000
The kar3p and kip2p motors function antagonistically at the spindle poles to influence cytoplasmic microtubule numbers
1998
Genes that cause aberrant cell morphology by overexpression in fission yeast: a role of a small GTP-binding protein Rho2 in cell morphogenesis
1998
Characterization of nuclear localizing sequences derived from yeast ribosomal protein L29.
1990
Localization of components involved in protein transport and processing through the yeast Golgi apparatus.
1991 StandoutNobel
Protein-protein interactions: methods for detection and analysis
1995
The NDA3 gene of fission yeast encodes β-tubulin: A cold-sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis
1984
Polypeptide translocation across the endoplasmic reticulum membrane.
1992 StandoutNobel
High Rates of Actin Filament Turnover in Budding Yeast and Roles for Actin in Establishment and Maintenance of Cell Polarity Revealed Using the Actin Inhibitor Latrunculin-A
1997
Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring
1996 StandoutNobel
Components of the yeast spindle and spindle pole body.
1990
The yeasts Rho1p and Pkc1p regulate the transport of chitin synthase III (Chs3p) from internal stores to the plasma membrane
2003 StandoutNobel
Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast.
1994
Cell Wall Stress Depolarizes Cell Growth via Hyperactivation of Rho1
1999
Topology and functional domains of Sec63p, an endoplasmic reticulum membrane protein required for secretory protein translocation.
1992 StandoutNobel
Fission yeast protein kinase C gene homologues are required for protoplast regeneration: a functional link between cell wall formation and cell shape control
1994
Chs6p-dependent Anterograde Transport of Chs3p from the Chitosome to the Plasma Membrane inSaccharomyces cerevisiae
1998 StandoutNobel
The Saccharomyces cerevisiae Kinesin-related Motor Kar3p Acts at Preanaphase Spindle Poles to Limit the Number and Length of Cytoplasmic Microtubules
1997
Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42.
1990
Use of a screen for synthetic lethal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saccharomyces cerevisiae.
1991
Sequence and domain organization of scruin, an actin-cross-linking protein in the acrosomal process of Limulus sperm.
1995
Regulation of cortical actin cytoskeleton assembly during polarized cell growth in budding yeast.
1995
SCF and Cullin/RING H2-Based Ubiquitin Ligases
1999
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Investigations into the control of cell form and polarity: the use of morphological mutants in fission yeast
1993 StandoutNobel
The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins
1997
The yeast nucleoporin Nup188p interacts genetically and physically with the core structures of the nuclear pore complex.
1996 StandoutNobel
Yeast RHO3 and RHO4 ras superfamily genes are necessary for bud growth, and their defect is suppressed by a high dose of bud formation genes CDC42 and BEM1.
1992
Localization of the Kar3 kinesin heavy chain-related protein requires the Cik1 interacting protein
1994
The dynamics of chromosome movement in the budding yeast Saccharomyces cerevisiae.
1989
Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.
1994 StandoutNobel
The Schizosaccharomyces pombe cdc3+ gene encodes a profilin essential for cytokinesis.
1994
Histone H2B repression causes cell-cycle-specific arrest in yeast: Effects on chromosomal segregation, replication, and transcription
1987
Tea2p Is a Kinesin-like Protein Required to Generate Polarized Growth in Fission Yeast
2000 StandoutNobel
MIF2 is required for mitotic spindle integrity during anaphase spindle elongation in Saccharomyces cerevisiae.
1993 StandoutNobel
Control of the yeast bud-site assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3.
1994
Novel Protein Kinases Ark1p and Prk1p Associate with and Regulate the Cortical Actin Cytoskeleton in Budding Yeast
1999
BIK1, a protein required for microtubule function during mating and mitosis in Saccharomyces cerevisiae, colocalizes with tubulin.
1990
A gene required for the separation of chromosomes on the spindle apparatus in yeast
1986
KAR1, a gene required for function of both intranuclear and extranuclear microtubules in yeast
1987
Distinct sequence determinants direct intracellular sorting and modification of a yeast vacuolar protease
1987
The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae
1988 StandoutScienceNobel
Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating.
1995
Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity.
1990
Cell Cycle–Regulated Attachment of the Ubiquitin-Related Protein Sumo to the Yeast Septins
1999 StandoutNobel
Actin is associated with the formation of the cell wall in reverting protoplasts of the fission yeast Schizosaccharomyces pombe
1989
A yeast gene essential for regulation of spindle pole duplication.
1988
The Schizosaccharomyces pombe cwg2+ gene codes for the beta subunit of a geranylgeranyltransferase type I required for beta-glucan synthesis.
1993
pVHL 19 is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation
1998 StandoutNobel
The SPA2 protein of yeast localizes to sites of cell growth.
1989
Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity
1997
Analysis of the Saccharomyces Spindle Pole by Matrix-assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry
1998
Isolation and characterization of PEP3, a gene required for vacuolar biogenesis in Saccharomyces cerevisiae.
1991
Use of a Screen for Synthetic Lethal and Multicopy Suppressee Mutants To Identify Two New Genes Involved in Morphogenesis in Saccharomyces cerevisiae
1991
Isolation and characterization of nuclear envelopes from the yeast Saccharomyces.
1995 StandoutNobel
Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly.
1992
SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex.
1992
Isolation of the yeast nuclear pore complex.
1993 StandoutNobel
Mitotic spindle function in Saccharomyces cerevisiae requires a balance between different types of kinesin-related motors.
1997
The SPA2 gene of Saccharomyces cerevisiae is important for pheromone-induced morphogenesis and efficient mating.
1990
A spacer protein in the Saccharomyces cerevisiae spindle poly body whose transcript is cell cycle-regulated.
1993
The subnuclear localization of tRNA ligase in yeast.
1987
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Cdc42p GTPase Is Involved in Controlling Polarized Cell Growth in Schizosaccharomyces pombe
1994
Polarization of cell growth in yeast II. The role of the cortical actin cytoskeleton
2000
Genetic interactions affecting touch sensitivity in Caenorhabditis elegans.
1996 StandoutNobel
Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product.
1991
nup1 mutants exhibit pleiotropic defects in nuclear pore complex function.
1994
The GTP-binding Protein Rho1p Is Required for Cell Cycle Progression and Polarization of the Yeast Cell
1999
WITH APOLOGIES TO SCHEHERAZADE: TAILS OF 1001 KINESIN MOTORS
1993
A Yeast Gene Essential for Regulation of Spindle Pole Duplication
1988
Isolation of yeast mutants defective in protein targeting to the vacuole.
1986
A chicken-yeast chimeric β-tubulin protein is incorporated into mouse microtubules in vivo
1986
Mitotic Spindle Positioning in Saccharomyces cerevisiae Is Accomplished by Antagonistically Acting Microtubule Motor Proteins
1997
Requirement for ESP1 in the nuclear division of Saccharomyces cerevisiae.
1992
Microtubules mediate mitochondrial distribution in fission yeast.
1996 StandoutNobel
Dynamics of cytoplasmic organelles in the cell cycle of the fission yeast Schizosaccharomyces pombe: three-dimensional reconstruction from serial sections
1989
Biogenesis of vacuolar membrane glycoproteins of yeast Saccharomyces cerevisiae.
1990 StandoutNobel
Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae
1993
Nup120p: a yeast nucleoporin required for NPC distribution and mRNA transport.
1995 StandoutNobel
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
Role of astral microtubules and actin in spindle orientation and migration in the budding yeast, Saccharomyces cerevisiae.
1992
Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast.
1990
Chs7p, a New Protein Involved in the Control of Protein Export from the Endoplasmic Reticulum that Is Specifically Engaged in the Regulation of Chitin Synthesis in Saccharomyces cerevisiae
1999
Lamin A, lamin B, and lamin B receptor analogues in yeast.
1989
Identification of Yeast Rho1p GTPase as a Regulatory Subunit of 1,3-β-Glucan Synthase
1996 Science
Mal3, the Fission Yeast Homologue of the Human APC-interacting Protein EB-1 Is Required for Microtubule Integrity and the Maintenance of Cell Form
1997
Identification and characterization of a yeast nucleolar protein that is similar to a rat liver nucleolar protein.
1988 StandoutNobel
Cdc42p GTPase is involved in controlling polarized cell growth in Schizosaccharomyces pombe.
1994
A new family of yeast nuclear pore complex proteins.
1992 StandoutNobel
Two Genes Required for Cell Fusion During Yeast Conjugation: Evidence for a Pheromone-Induced Surface Protein
1987
Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae.
1994
The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe
1988
Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage.
1990 StandoutNobel
Kinesin-related proteins required for assembly of the mitotic spindle.
1992
Growth Polarity And Cytokinesis In Fission Yeast: The Role Of The Cytoskeleton
1986
Three-dimensional analysis of morphogenesis induced by mating pheromone α factor in saccharomyces cerevisiae
1989 StandoutNobel
DNA topoisomerase II is required at the time of mitosis in yeast
1985
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein.
1987
Separate domains of KAR1 mediate distinct functions in mitosis and nuclear fusion
1992
Genetic analysis of cell morphogenesis in fission yeast--a role for casein kinase II in the establishment of polarized growth.
1994 StandoutNobel
Regulation of Cell Polarity by Microtubules in Fission Yeast
1998 StandoutNobel
To shape a cell: an inquiry into the causes of morphogenesis of microorganisms
1990
Three-dimensional ultrastructural analysis of the Saccharomyces cerevisiae mitotic spindle.
1995
Protein Localization and Membrane Traffic in Yeast
1985 StandoutNobel
Diverse effects of beta-tubulin mutations on microtubule formation and function.
1988
Identification of a nuclear localization signal of a yeast ribosomal protein.
1985
The NSR1 gene encodes a protein that specifically binds nuclear localization sequences and has two RNA recognition motifs.
1991
Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1.
1989
Identification of Novel Temperature-sensitive Lethal Alleles in Essential β-Tubulin and Nonessential α2-Tubulin Genes as Fission Yeast Polarity Mutants
1998
POM152 is an integral protein of the pore membrane domain of the yeast nuclear envelope.
1994
Transmission and scanning electron microscopic examination of intracellular organelles in freeze‐substituted Kloeckera and Saccharomyces cerevisiae Yeast Cells
1987
The Kinesin-related Proteins, Kip2p and Kip3p, Function Differently in Nuclear Migration in Yeast
1998
Molecular Linkage Underlying Microtubule Orientation Toward Cortical Sites in Yeast
2000 Science
Components of microtubular structures in Saccharomyces cerevisiae.
1986
Nuclear congression and membrane fusion: two distinct events in the yeast karyogamy pathway.
1994 StandoutNobel
CIK1: a developmentally regulated spindle pole body-associated protein important for microtubule functions in Saccharomyces cerevisiae.
1992
Works of A.E. Adams being referenced
1 The Yeast Cytoskeleton
1997
Dominant suppressors of yeast actin mutations that are reciprocally suppressed.
1989
Requirement of yeast fimbrin for actin organization and morphogenesis in vivo
1991 Nature
A role for ubiquitinylation and the cytosolic proteasome in turnover of mitochondrial uncoupling protein 1 (UCP1)
2012
Actin mutations that show suppression with fimbrin mutations identify a likely fimbrin-binding site on actin.
1994
Cdc53p Acts in Concert with Cdc4p and Cdc34p To Control the G1-to-S-Phase Transition and Identifies a Conserved Family of Proteins
1996
Purification of profilin from Saccharomyces cerevisiae and analysis of profilin-deficient cells.
1990
A Yeast Actin-Binding Protein Is Encoded by SAC6 , a Gene Found by Suppression of an Actin Mutation
1989 Science
Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae.
1984 Standout
Chapter 19 Fluorescence Microscopy Methods for Yeast
1989
Isoform-Specific Complementation of the Yeast sac6 Null Mutation by Human Fimbrin
1995
Unexpected combinations of null mutations in genes encoding the actin cytoskeleton are lethal in yeast.
1993
Cellular Morphogenesis in the Yeast Saccharomyces Cerevisiae.
1984
Functions of microtubules in the Saccharomyces cerevisiae cell cycle.
1988
[40] Immunofluorescence methods for yeast
1991
Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces.
1984
[51] Staining of actin with fluorochrome-conjugated phalloidin
1991
A Septin-based Hierarchy of Proteins Required for Localized Deposition of Chitin in the Saccharomyces cerevisiae Cell Wall
1997
CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae.
1990