Citation Impact
Citing Papers
LIM Protein KyoT2 Negatively Regulates Transcription by Association with the RBP-J DNA-Binding Protein
1998 StandoutNobel
Numb-Associated Kinase Interacts with the Phosphotyrosine Binding Domain of Numb and Antagonizes the Function of Numb In Vivo
1998
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
neurotic , a novel maternal neurogenic gene, encodes an O -fucosyltransferase that is essential for Notch-Delta interactions
2003
A conditional tissue-specific transgene expression system using inducible GAL4
2001
A Genomewide Search for Ribozymes Reveals an HDV-Like Sequence in the Human CPEB3 Gene
2006 StandoutScienceNobel
The Xenopus homolog of Drosophila Suppressor of Hairless mediates Notch signaling during primary neurogenesis
1997
A DNA Transcription Code for Cell-Specific Gene Activation by Notch Signaling
2005
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment
2006
Repression by Suppressor of Hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo
2000
Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiation
1997
The Notch 3 intracellular domain represses Notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters
1999
Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes
2005
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects.
1995
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons
1993
Functional Interaction between SEL-10, an F-box Protein, and the Nuclear Form of Activated Notch1 Receptor
2001 StandoutNobel
The WRPW Motif of the Hairy-Related Basic Helix-Loop-Helix Repressor Proteins Acts as a 4-Amino-Acid Transcription Repression and Protein-Protein Interaction Domain
1996
Lethal of Scute requires overexpression of Daughterless to elicit ectopic neuronal development during embryogenesis in Drosophila
1997
Drosophila FMRP regulates microtubule network formation and axonal transport of mitochondria
2010
The achaete-scute complex as an integrating device
1998
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins
2002
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
The Bearded box, a novel 3′ UTR sequence motif, mediates negative post-transcriptional regulation of Bearded and Enhancer of split Complex gene expression
1997
The metalloprotease-disintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs
1997
X-MyT1, a Xenopus C2HC-Type Zinc Finger Protein with a Regulatory Function in Neuronal Differentiation
1996
Notch pathway: Making sense of Suppressor of Hairless
2001
Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila
1996
Bearded Family Members Inhibit Neuralized-Mediated Endocytosis and Signaling Activity of Delta in Drosophila
2006
The K box, a conserved 3′ UTR sequence motif, negatively regulates accumulation of Enhancer of split Complex transcripts
1998
Delta-1 Activation of Notch-1 Signaling Results in HES-1 Transactivation
1998
Notch Signaling Suppresses IgH Gene Expression in Chicken B Cells: Implication in Spatially Restricted Expression of Serrate2/Notch1 in the Bursa of Fabricius
2001
Ionotropic Glutamate Receptors & CNS Disorders
2008
Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
2011 Standout
Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing
2006 Nature
lincRNAs: Genomics, Evolution, and Mechanisms
2013 Standout
LIN-12/Notch signaling: lessons from worms and flies
1998
Target Selectivity of Vertebrate Notch Proteins
2005
Roles of the ankyrin repeats and C-terminal region of the mouse Notch1 intracellular region
1998 StandoutNobel
Asymmetric Rab11 Endosomes Regulate Delta Recycling and Specify Cell Fate in the Drosophila Nervous System
2005
MicroRNAs
2004 Standout
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Reliable prediction of regulator targets using 12 Drosophila genomes
2007
Inhibition of activin receptor signaling promotes neuralization in Xenopus
1994
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
The Groucho/Transducin-like Enhancer of split Transcriptional Repressors Interact with the Genetically Defined Amino-terminal Silencing Domain of Histone H3
1997
The Drosophila Tumor Suppressor vps25 Prevents Nonautonomous Overproliferation by Regulating Notch Trafficking
2005
Oncogenic Forms of NOTCH1 Lacking Either the Primary Binding Site for RBP-Jκ or Nuclear Localization Sequences Retain the Ability to Associate with RBP-Jκ and Activate Transcription
1997
Interactions between the cellular and humoral immune responses in Drosophila
2000
Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation
1996 StandoutNobel
Notch Receptors, Partners and Regulators: From Conserved Domains to Powerful Functions
1998
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
Opposite thermosensor in fruitfly and mouse
2003 StandoutNatureNobel
Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity
1994
The Drosophila Circadian Network Is a Seasonal Timer
2007 StandoutNobel
The role of Notch in tumorigenesis: oncogene or tumour suppressor?
2003
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
A microRNA Mediates EGF Receptor Signaling and Promotes Photoreceptor Differentiation in the Drosophila Eye
2005
Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development
1996
The REF-1 Family of bHLH Transcription Factors Pattern C. elegans Embryos through Notch-Dependent and Notch-Independent Pathways
2005
Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs
2005
The mammalian transcriptional repressor RBP (CBF1) targets TFIID and TFIIA to prevent activated transcription
1998
Regulation of B cell development by Notch/RBP-J signaling
2003 StandoutNobel
The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force
2017
painless, a Drosophila Gene Essential for Nociception
2003
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
Control of Daughter Cell Fates during Asymmetric Division: Interaction of Numb and Notch
1996
Regulation of Marginal Zone B Cell Development by MINT, a Suppressor of Notch/RBP-J Signaling Pathway
2003 StandoutNobel
Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections
2001 StandoutNobel
Transcriptional repression by Suppressor of Hairless involves the binding of a Hairless-dCtBP complex in Drosophila
2001
Bre1 Is Required for Notch Signaling and Histone Modification
2005
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
Regulation of lymphocyte development by Notch signaling
2007 StandoutNobel
Hedgehog Induces Opposite Changes in Turnover and Subcellular Localization of Patched and Smoothened
2000
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
The Ins and Outs of Notch Signaling
1997
A Novel Proteolytic Cleavage Involved in Notch Signaling
2000 Standout
MicroRNA Pathways in Flies and Worms
2003 StandoutNobel
Notch signalling: a simple pathway becomes complex
2006 Standout
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Regulation of Notch Endosomal Sorting and Signaling by Drosophila Nedd4 Family Proteins
2004
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos
1998
A histone deacetylase corepressor complex regulates the Notch signal transduction pathway
1998
Functional Interaction between the Mouse Notch1 Intracellular Region and Histone Acetyltransferases PCAF and GCN5
2000 StandoutNobel
Indirect evidence for Delta-dependent intracellular processing of Notch in Drosophila embryos
1998
Spatially Restricted Factors Cooperate with Notch in the Regulation of Enhancer of split Genes
2000
The immune response of Drosophila
2003 StandoutNatureNobel
Regulation of vertebrate neural cell fate by transcription factors
1996
Fragile X-related protein and VIG associate with the RNA interference machinery
2002
Regulation of local mRNA translation
2004
A Notch-Independent Activity of Suppressor of Hairless Is Required for Normal Mechanoreceptor Physiology
2000
Proneural genes and the specification of neural cell types
2002 Standout
Notch–RBP-J signaling is involved in cell fate determination of marginal zone B cells
2002 StandoutNobel
The Drosophila ortholog of vertebrate TRPA1 regulates thermotaxis
2005 StandoutNobel
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
The role of Drosophila Piezo in mechanical nociception
2012 StandoutNatureNobel
Notch1 Expression in Early Lymphopoiesis Influences B versus T Lineage Determination
1999 Standout
A Subset of Dorsal Neurons Modulates Circadian Behavior and Light Responses in Drosophila
2007
Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene
1996 Nature
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Are Complex Behaviors Specified by Dedicated Regulatory Genes? Reasoning from Drosophila
2001 StandoutNobel
Identification of neurogenin, a Vertebrate Neuronal Determination Gene
1996
MEP-1 and a Homolog of the NURD Complex Component Mi-2 Act Together to Maintain Germline-Soma Distinctions in C. elegans
2002 StandoutNobel
Coupled oscillators control morning and evening locomotor behaviour of Drosophila
2004 StandoutNatureNobel
The functions of animal microRNAs
2004 StandoutNatureNobel
Default repression and Notch signaling: Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless
2002
Genetics and molecular biology of rhythms in Drosophila and other insects
2003 StandoutNobel
Activation of the Drosophila NF‐κB factor Relish by rapid endoproteolytic cleavage
2000
Numb and α‐Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs
2005
Roles of the RAM and ANK domains in signaling by the C. elegans GLP-1 receptor.
1996
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
Nuclear Access and Action of Notch In Vivo
1998
The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage.
1996
Cis-interactions between Delta and Notch modulate neurogenic signalling in Drosophila
1998
Drosophila Hsc70-4 Is Critical for Neurotransmitter Exocytosis In Vivo
2001
Subcellular localization of Suppressor of Hairless in Drosophila sense organ cells during Notch signalling
1996
A hierarchy of cross-regulation involving Notch, wingless, vestigial and cut organizes the dorsal/ventral axis of the Drosophila wing
1996
Gene Regulation: Gene Control Network in Development
2007
The molecular logic of Notch signaling – a structural and biochemical perspective
2008
A model Notch response element detects Suppressor of Hairless–dependent molecular switch
2001
Dual-Tagging Gene Trap of Novel Genes inDrosophila melanogaster
2001
Dual Activation of the Drosophila Toll Pathway by Two Pattern Recognition Receptors
2003 StandoutScienceNobel
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Neural Science
2000 StandoutNobel
A Notch-independent function of Suppressor of Hairless during the development of the bristle sensory organ precursor cell ofDrosophila
2003
split endsencodes large nuclear proteins that regulate neuronal cell fate and axon extension in theDrosophilaembryo
2000
Echinoid synergizes with the Notch signaling pathway inDrosophilamesothorax bristle patterning
2003
p300 and PCAF Act Cooperatively To Mediate Transcriptional Activation from Chromatin Templates by Notch Intracellular Domains In Vitro
2002
Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements
1997
Conservation of the Notch signalling pathway in mammalian neurogenesis
1997 StandoutNobel
The bantam Gene Regulates Drosophila Growth
2002
Isolation and Functional Analysis of a cDNA for Human Jagged2, a Gene Encoding a Ligand for the Notch1 Receptor
1997
RBP-L, a Transcription Factor Related to RBP-Jκ
1997 StandoutNobel
Notch Inhibition of E47 Supports the Existence of a Novel Signaling Pathway
1998
Spatiotemporal Gene Expression Targeting with the TARGET and Gene-Switch Systems in Drosophila
2004
Notch Signaling: Cell Fate Control and Signal Integration in Development
1999 StandoutScience
Notch signalling mediates segmentation of the Drosophila leg
1998
Cell proliferation control by Notch signaling in Drosophila development
1998
THE LIN-12/Notch SIGNALING PATHWAY AND ITS REGULATION
1997
Dominant-negative mutation in the β2 and β6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage
1999
SKIP, a CBF1-Associated Protein, Interacts with the Ankyrin Repeat Domain of NotchIC To Facilitate NotchIC Function
2000
Works of Adina Bailey being referenced
Lateral inhibition in proneural clusters: cis-regulatory logic and default repression by Suppressor of Hairless
2005
XASH1, a Xenopus homolog of achaete-scute: a proneural gene in anterior regions of the vertebrate CNS
1993
Drosophila Fragile X-Related Gene Regulates the MAP1B Homolog Futsch to Control Synaptic Structure and Function
2001
HairlessPromotes Stable Commitment to the Sensory Organ Precursor Cell Fate by Negatively Regulating the Activity of theNotchSignaling Pathway
1995
Systematic gain-of-function genetics in Drosophila
1998
Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity.
1995
Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaete.
1994
Identification of putative noncoding polyadenylated transcripts in Drosophila melanogaster
2005