Citation Impact
Citing Papers
Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems
2014
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
2020 StandoutNobel
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Immune loss as a driver of coexistence during host-phage coevolution
2018
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
2016 StandoutScience
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system
2016
Systematic discovery of antiphage defense systems in the microbial pangenome
2018 Science
RNA-Guided Human Genome Engineering via Cas9
2013 StandoutScience
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
2012 StandoutScienceNobel
Machine learning predicts new anti-CRISPR proteins
2020 StandoutNobel
Structures of the CRISPR genome integration complex
2017 StandoutScienceNobel
2014
Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR–Cas system
2016
The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans
2019 StandoutNobel
Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle
2023 StandoutNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Quorum Sensing Controls Adaptive Immunity through the Regulation of Multiple CRISPR-Cas Systems
2016
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Major bacterial lineages are essentially devoid of CRISPR-Cas viral defence systems
2016
CRISPR-based technologies: prokaryotic defense weapons repurposed
2014
Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression
2014
Parasite Exposure Drives Selective Evolution of Constitutive versus Inducible Defense
2015
Classification and evolution of type II CRISPR-Cas systems
2014 StandoutNobel
Live virus-free or die: coupling of antivirus immunity and programmed suicide or dormancy in prokaryotes
2012
Pervasive generation of oppositely oriented spacers during CRISPR adaptation
2014
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
CRISPR–Cas systems: beyond adaptive immunity
2014
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Cytotoxic Chromosomal Targeting by CRISPR/Cas Systems Can Reshape Bacterial Genomes and Expel or Remodel Pathogenicity Islands
2013
Engineering functional thermostable proteins using ancestral sequence reconstruction
2022
Clustered regularly interspaced short palindromic repeats (CRISPRs): the hallmark of an ingenious antiviral defense mechanism in prokaryotes
2011
Candidate Phyla Radiation Roizmanbacteria From Hot Springs Have Novel and Unexpectedly Abundant CRISPR-Cas Systems
2019 StandoutNobel
CRISPR Inhibition of Prophage Acquisition in Streptococcus pyogenes
2011
To acquire or resist: the complex biological effects of CRISPR–Cas systems
2014
Foreign DNA capture during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
Processing-Independent CRISPR RNAs Limit Natural Transformation in Neisseria meningitidis
2013
Identification, structural, and biochemical characterization of a group of large Csn2 proteins involved in CRISPR‐mediated bacterial immunity
2012
Dealing with the Evolutionary Downside of CRISPR Immunity: Bacteria and Beneficial Plasmids
2013
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
Programmable RNA recognition and cleavage by CRISPR/Cas9
2014 StandoutNatureNobel
Unravelling the structural and mechanistic basis of CRISPR–Cas systems
2014
Not all predicted CRISPR–Cas systems are equal: isolated cas genes and classes of CRISPR like elements
2017
A bacteriophage encodes its own CRISPR/Cas adaptive response to evade host innate immunity
2013 Nature
Comparative genomics of defense systems in archaea and bacteria
2013
Characterization of the CRISPR/Cas Subtype I-A System of the Hyperthermophilic Crenarchaeon Thermoproteus tenax
2012
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
Discovery and Characterization of Cas9 Inhibitors Disseminated across Seven Bacterial Phyla
2019
Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system
2012
Impact of CRISPR immunity on the emergence and virulence of bacterial pathogens
2014
CRISPR-based adaptive immune systems
2011
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
Bacteria–phage coevolution as a driver of ecological and evolutionary processes in microbial communities
2014
CRISPR Interference Directs Strand Specific Spacer Acquisition
2012
De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints
2016
CRISPR-Cas and restriction–modification systems are compatible and increase phage resistance
2013
Transcriptome analysis of Sulfolobus solfataricus infected with two related fuselloviruses reveals novel insights into the regulation of CRISPR-Cas system
2015
Campylobacter jejuni acquire new host-derived CRISPR spacers when in association with bacteriophages harboring a CRISPR-like Cas4 protein
2015
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
A dual function of the CRISPR–Cas system in bacterial antivirus immunity and DNA repair
2010
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Type I CRISPR-Cas targets endogenous genes and regulates virulence to evade mammalian host immunity
2016
Type I-E CRISPR-Cas Systems Discriminate Target from Non-Target DNA through Base Pairing-Independent PAM Recognition
2013
A CRISPR/Cas system mediates bacterial innate immune evasion and virulence
2013 Nature
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System
2015 StandoutNobel
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
2013 StandoutNobel
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
CRISPR-Cas Systems in Bacteria and Archaea: Versatile Small RNAs for Adaptive Defense and Regulation
2011
A New Group of Phage Anti-CRISPR Genes Inhibits the Type I-E CRISPR-Cas System of Pseudomonas aeruginosa
2014
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems
2016 Science
The CRISPRs, They Are A-Changin': How Prokaryotes Generate Adaptive Immunity
2012
Improving Protein Expression, Stability, and Function with ProteinMPNN
2024 StandoutNobel
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
A CRISPR with Roles in Myxococcus xanthus Development and Exopolysaccharide Production
2014
Classification and quantification of bacteriophage taxa in human gut metagenomes
2014
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
2015 StandoutScienceNobel
The Discovery, Mechanisms, and Evolutionary Impact of Anti-CRISPRs
2017
The chemistry of Cas9 and its CRISPR colleagues
2017 StandoutNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
The subtype I-F CRISPR–Cas system influences pathogenicity island retention in Pectobacterium atrosepticum via crRNA generation and Csy complex formation
2013
Costs of CRISPR-Cas-mediated resistance inStreptococcus thermophilus
2015
Evolution and Ecology of CRISPR
2016
CRISPR-Cas: biology, mechanisms and relevance
2016 StandoutNobel
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
2016 StandoutScience
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference
2014 StandoutNobel
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein
2017
Rational design of a split-Cas9 enzyme complex
2015 StandoutNobel
Nature and Intensity of Selection Pressure on CRISPR-Associated Genes
2011
CRISPR: New Horizons in Phage Resistance and Strain Identification
2012
Covalent Modification of Bacteriophage T4 DNA Inhibits CRISPR-Cas9
2015
Cas9 function and host genome sampling in Type II-A CRISPR–Cas adaptation
2015
CRISPR-Mediated Adaptive Immune Systems in Bacteria and Archaea
2013
Viral Diversity Threshold for Adaptive Immunity in Prokaryotes
2012
CRISPR-Cas Adaptive Immune Systems of the Sulfolobales: Unravelling Their Complexity and Diversity
2015
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
CRISPR-Cas: Adapting to change
2017 Science
The ecology of the microbiome: Networks, competition, and stability
2015 StandoutScience
Helicase dissociation and annealing of RNA-DNA hybrids by Escherichia coli Cas3 protein
2011
Function and Regulation of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) / CRISPR Associated (Cas) Systems
2012
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
2013 StandoutNobel
Friendly Fire: Biological Functions and Consequences of Chromosomal Targeting by CRISPR-Cas Systems
2016
Evolutionary Dynamics of the Prokaryotic Adaptive Immunity System CRISPR-Cas in an Explicit Ecological Context
2013
In vivo activity of CRISPR‐mediated virus defence in a hyperthermophilic archaeon
2011
Mechanisms and clinical importance of bacteriophage resistance
2021
No evidence of inhibition of horizontal gene transfer by CRISPR–Cas on evolutionary timescales
2015
Works of Adi Stern being referenced
Self-targeting by CRISPR: gene regulation or autoimmunity?
2010
CRISPR targeting reveals a reservoir of common phages associated with the human gut microbiome
2012
Holding a grudge
2013
The phage‐host arms race: Shaping the evolution of microbes
2010
Assessing the prediction fidelity of ancestral reconstruction by a library approach
2015