Citation Impact
Citing Papers
Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells
2002 StandoutScienceNobel
Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization
2004 StandoutScienceNobel
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Lipid Rafts As a Membrane-Organizing Principle
2009 StandoutScience
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Visualization of the movement of single histidine kinase molecules in live Caulobacter cells
2004 StandoutNobel
Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes
2018 StandoutScience
Plant Cuticular Lipid Export Requires an ABC Transporter
2004 StandoutScience
Fast molecular tracking maps nanoscale dynamics of plasma membrane lipids
2010 StandoutNobel
1 Developmental roles and clinical significance of Hedgehog signaling
2003
Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol
1999
Astrocytes: biology and pathology
2009 Standout
Use of cyclodextrins for manipulating cellular cholesterol content
1997
Niemann-Pick C1 Functions Independently of Niemann-Pick C2 in the Initial Stage of Retrograde Transport of Membrane-impermeable Lysosomal Cargo
2009
Protein Kinase A and G Protein-coupled Receptor Kinase Phosphorylation Mediates β-1 Adrenergic Receptor Endocytosis through Different Pathways
2003 StandoutNobel
Intracellular sterol dynamics
2009
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
2003 StandoutNature
Arabidopsis Sterol Endocytosis Involves Actin-Mediated Trafficking via ARA6-Positive Early Endosomes
2003
DAF-9, a cytochrome P450 regulatingC. eleganslarval development and adult longevity
2002
Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders
2007
Role of Niemann-Pick Type C1 Protein in Intracellular Trafficking of Low Density Lipoprotein-derived Cholesterol
2000
Biosynthesis and secretion of plant cuticular wax
2002
Regulation of V2 Vasopressin Receptor Degradation by Agonist-promoted Ubiquitination
2003 StandoutNobel
Hedgehog and Patched in Neural Development and Disease
1998
Amelioration of enteric neuropathology in a mouse model of Niemann‐Pick C by Npc1 expression in enteric glia
2009
Fate of Endogenously Synthesized Cholesterol in Niemann-Pick Type C1 Cells
2000
Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport
1999
Multi-protein assemblies underlie the mesoscale organization of the plasma membrane
2014 StandoutNobel
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes
2016
Of Pesticides and Men: a California Story of Genes and Environment in Parkinson’s Disease
2016
Circulation of Cholesterol between Lysosomes and the Plasma Membrane
1998
The hedgehog signaling network
2003
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock
2002 Standout
Vertebrate Smoothened functions at the primary cilium
2005 StandoutNature
Elucidation and Chemical Modulation of Sulfolipid-1 Biosynthesis in Mycobacterium tuberculosis
2011 StandoutNobel
Hedgehog Induces Opposite Changes in Turnover and Subcellular Localization of Patched and Smoothened
2000
Cholesterol efflux pathways and other potential mechanisms involved in the athero‐protective effect of high density lipoproteins
2008
A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis
2003
Astrocyte‐only Npc1 reduces neuronal cholesterol and triples life span of Npc1–/– mice
2008
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Late Endosomal Cholesterol Accumulation Leads to Impaired Intra-Endosomal Trafficking
2007
Lysosomal storage disorders
2005
Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
2011 StandoutNature
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells
2020
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
1996 StandoutNature
TRP channels as cellular sensors
2003 StandoutNature
Roles of lipid rafts in membrane transport
2001
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
2000 StandoutNature
Hedgehog signaling in animal development: paradigms and principles
2001 Standout
Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
2008
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Cholesterol Depletion Suppresses the Translational Diffusion of Class II Major Histocompatibility Complex Proteins in the Plasma Membrane
2004 StandoutNobel
Cholesterol Depletion of Caveolae Causes Hyperactivation of Extracellular Signal-related Kinase (ERK)
1998
Cholesterol Distribution in Living Cells: Fluorescence Imaging Using Dehydroergosterol as a Fluorescent Cholesterol Analog
1998
Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel
2000
Evidence for a Niemann–Pick C (NPC) Gene Family: Identification and Characterization of NPC1L1
2000
Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis
2011 Standout
Multidrug permeases and subcellular cholesterol transport
2001
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
2003 StandoutNature
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Late Endosomes: Sorting and Partitioning in Multivesicular Bodies
2001
The endocytic pathway: a mosaic of domains
2001
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Acute cholesterol depletion inhibits clathrin-coated pit budding
1999
Cholesterol as Modulator of Receptor Function
1997
Biosynthesis of the Caenorhabditis elegans dauer pheromone
2009 StandoutNobel
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Functional rafts in cell membranes
1997 StandoutNature
Traffic, polarity, and detergent solubility of a glycosylphosphatidylinositol-anchored protein after LDL-deprivation of MDCK cells.
1996
The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human disease and development proteins.
1999
Late endosome motility depends on lipids via the small GTPase Rab7
2002
Gene Regulatory Networks and the Evolution of Animal Body Plans
2006 StandoutScience
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
Patched1 Regulates Hedgehog Signaling at the Primary Cilium
2007 StandoutScience
The Organocatalytic Approach to Enantiopure 2H‐ and 3H‐Pyrroles: Inhibitors of the Hedgehog Signaling Pathway
2016 StandoutNobel
Fast structural responses of gap junction membrane domains to AB5 toxins
2013 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Dynamics of putative raft-associated proteins at the cell surface
2004
Extraction of Cholesterol with Methyl-β-Cyclodextrin Perturbs Formation of Clathrin-coated Endocytic Vesicles
1999
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
Mammalian ABC Transporters in Health and Disease
2002
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo
2001
Neoplastic transformation of guinea pig fetal cells in culture induced by chemical carcinogens.
1975
Cholesterol Synthesis Inhibitor U18666A and the Role of Sterol Metabolism and Trafficking in Numerous Pathophysiological Processes
2009
Global analysis of dauer gene expression inCaenorhabditis elegans
2003
Anatomy and Dynamics of a Supramolecular Membrane Protein Cluster
2007 StandoutScienceNobel
Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid
1983 StandoutScience
Sonic Hedgehog Induces the Segregation of Patched and Smoothened in Endosomes
2002
Molecular diversity of astrocytes with implications for neurological disorders
2004
New directions in single-molecule imaging and analysis
2007 StandoutNobel
Filipin-dependent Inhibition of Cholera Toxin: Evidence for Toxin Internalization and Activation through Caveolae-like Domains
1998
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Hedgehog-Gli Signaling Pathway Inhibitors as Anticancer Agents
2009
Disturbed Cholesterol Traffic but Normal Proteolytic Function in LAMP-1/LAMP-2 Double-deficient Fibroblasts
2004
Deficiency of Niemann-Pick Type C-1 Protein Impairs Release of Human Immunodeficiency Virus Type 1 and Results in Gag Accumulation in Late Endosomal/Lysosomal Compartments
2009
Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene
1997 Science
Niemann-Pick C1 Like 1 Protein Is Critical for Intestinal Cholesterol Absorption
2004 StandoutScience
Identification of HE1 as the Second Gene of Niemann-Pick C Disease
2000 Science
Cholesterol Sensing, Trafficking, and Esterification
2006
Sphingolipid metabolites: Members of a new class of lipid second messengers
1995
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Adele Cooney being referenced
Intracellular Trafficking of Cholesterol Monitored with a Cyclodextrin
1996
The ABCA1 Transporter Modulates Late Endocytic Trafficking
2004
Type C Niemann-Pick Disease: Use of Hydrophobic Amines to Study Defective Cholesterol Transport
1991
The Niemann-Pick C1 Protein Resides in a Vesicular Compartment Linked to Retrograde Transport of Multiple Lysosomal Cargo
1999
Cellular Localization and Trafficking of the Human ABCA1 Transporter
2001
Cyclopamine Inhibition of Sonic Hedgehog Signal Transduction Is Not Mediated through Effects on Cholesterol Transport
2000
Niemann‐Pick type‐C disease: Deficient intracellular transport of exogenously derived cholesterol
1992
Tumor‐specific and forssman antigens of guinea‐pig hepatoma cells: Comparison of tumor cells grown in vivo and in vitro
1975
Sterol-modulated Glycolipid Sorting Occurs in Niemann-Pick C1 Late Endosomes
2001
Substantial narrowing of the Niemann–Pick C candidate interval by yeast artificial chromosome complementation
1997
Cessation of rapid late endosomal tubulovesicular trafficking in Niemann–Pick type C1 disease
2001
Localization of Niemann–Pick C1 protein in astrocytes: Implications for neuronal degeneration in Niemann– Pick type C disease
1999
Rotenone decreases intracellular aldehyde dehydrogenase activity: implications for the pathogenesis of Parkinson's disease
2015
Mucolipidosis IV consists of one complementation group
1999