Citation Impact
Citing Papers
Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
2010 StandoutScience
Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells
2002
Molecular imaging in drug development
2008 Standout
Dopamine Receptor-Interacting Protein 78 Acts as a Molecular Chaperone for CCR5 Chemokine Receptor Signaling Complex Organization
2012
Hepatic stellate cells as key target in liver fibrosis
2017
RNA-seq analysis of Drosophila clock and non-clock neurons reveals neuron-specific cycling and novel candidate neuropeptides
2017 StandoutNobel
G protein coupled receptor structure and activation
2006 StandoutNobel
Bowel Disorders
2016 Standout
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
2006 Standout
The delta opioid receptor: an evolving target for the treatment of brain disorders
2011
Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
2009 StandoutNobel
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
2006 StandoutNobel
Marine natural products
1990 Standout
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
WNT and β-catenin signalling: diseases and therapies
2004 Standout
Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer
2009 StandoutNobel
G protein-coupled receptor interacting proteins: Emerging roles in localization and signal transduction
2002
Optogenetics: 10 years of microbial opsins in neuroscience
2015 Standout
Modulation of gastrointestinal function by MuDelta, a mixed µ opioid receptor agonist/ µ opioid receptor antagonist
2012
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
The mini-driver model of polygenic cancer evolution
2015 StandoutNobel
Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization
2003
Hepatocellular carcinoma
2021 Standout
Heterodimerization of G-protein-coupled receptors: pharmacology, signaling and trafficking
2001
How Ligands Illuminate GPCR Molecular Pharmacology
2017
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
2008 Standout
Molecular Dynamics Simulation for All
2018 Standout
Targeting CB2-GPR55 Receptor Heteromers Modulates Cancer Cell Signaling
2014
Increasingly accurate dynamic molecular models of G-protein coupled receptor oligomers: Panacea or Pandora's box for novel drug discovery?
2009
Facilitation of μ-Opioid Receptor Activity by Preventing δ-Opioid Receptor-Mediated Codegradation
2011
Historical review: A brief history and personal retrospective of seven-transmembrane receptors
2004 StandoutNobel
Interleukin-6 expression and regulation in astrocytes
1999
Oligomeric potential of the M2 muscarinic cholinergic receptor
2004
C5a Receptor Oligomerization
2003
Spatiotemporal Control of Opioid Signaling and Behavior
2015
Role of delivery and trafficking of δ-opioid peptide receptors in opioid analgesia and tolerance
2006
Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling
2013 StandoutNobel
A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface
2004
G Protein-Coupled Receptor Heteromerization: A Role in Allosteric Modulation of Ligand Binding
2011
Short Neuropeptide F Is a Sleep-Promoting Inhibitory Modulator
2013 StandoutNobel
Ligand-dependent Inhibition of Oligomerization at the Human Thyrotropin Receptor
2002
Autoradiographic localization of dopamine D1 and D2 receptors in rat nucleus accumbens: Resistance to differential rearing conditions
1991 Standout
Oligomerization of Wild Type and Nonfunctional Mutant Angiotensin II Type I Receptors Inhibits Gαq Protein Signaling but Not ERK Activation
2004
Interleukin-6 overexpression as a marker of malignancy in human gliomas
2001
β-Arrestin 2-Dependent Angiotensin II Type 1A Receptor-Mediated Pathway of Chemotaxis
2005 StandoutNobel
The development and modulation of nociceptive circuitry
2006
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Endogenous Peptide Discovery of the Rat Circadian Clock
2009
Effect of modulating the allosteric sites of N-methyl-D-aspartate receptors in ischemia-reperfusion induced acute kidney injury
2013
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Heterodimerization of G Protein-Coupled Receptors: Specificity and Functional Significance
2005
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
NPY receptors as potential targets for anti‐obesity drug development
2011
The functional and anatomical dissection of somatosensory subpopulations using mouse genetics
2014
Dissociation of the Opioid Receptor Mechanisms that Control Mechanical and Heat Pain
2009
Binding of Orthosteric Ligands to the Allosteric Site of the M2 Muscarinic Cholinergic Receptor
2008
Hydrocodone and morphine possess similar rewarding effects and reduce erk and creb phosphorylation in the nucleus accumbens
2012
Reduced Cell Surface Expression of CCR5 in CCR5Δ32 Heterozygotes Is Mediated by Gene Dosage, Rather Than by Receptor Sequestration
2002 StandoutNobel
Structure of the δ-opioid receptor bound to naltrindole
2012 StandoutNatureNobel
A Pluridimensional View of Biased Agonism
2016
Structure and dynamics of the M3 muscarinic acetylcholine receptor
2012 StandoutNatureNobel
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
Seven-transmembrane receptors
2002 StandoutNobel
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Are GPCRs Still a Source of New Targets?
2013
SEC23-SEC31 the Interface Plays Critical Role for Export of Procollagen from the Endoplasmic Reticulum
2012 StandoutNobel
Fine-tuning of GPCR activity by receptor-interacting proteins
2009
Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma
2010
Imaging chemokine receptor dimerization with firefly luciferase complementation
2008
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
2012 Standout
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Imaging protein–protein interactions in living subjects
2005
DREADDs (Designer Receptors Exclusively Activated by Designer Drugs): Chemogenetic Tools with Therapeutic Utility
2014
Oligomerization of G Protein-Coupled Receptors: Past, Present, and Future
2004
Identification of a Potent and Selective Cannabinoid CB1Receptor Antagonist fromAuxarthron reticulatum
2011
Activation of G Protein–Coupled Receptors: Beyond Two-State Models and Tertiary Conformational Changes
2007
Targeted Mass Spectrometry Approach Enabled Discovery of O-Glycosylated Insulin and Related Signaling Peptides in Mouse and Human Pancreatic Islets
2017
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis
2020 StandoutNobel
Probing Single Biomolecules in Solution Using the Anti-Brownian Electrokinetic (ABEL) Trap
2012 StandoutNobel
Chaperone-Assisted Protein Folding Is Critical for Yellow Fever Virus NS3/4A Cleavage and Replication
2016 StandoutNobel
β-Arrestins and Cell Signaling
2007 StandoutNobel
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
2003 StandoutScience
The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice
2018 StandoutNobel
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
2014 Standout
Click-Chemistry-Mediated Synthesis of Selective Melanocortin Receptor 4 Agonists
2017 StandoutNobel
IL-17A Enhances the Expression of Profibrotic Genes through Upregulation of the TGF-β Receptor on Hepatic Stellate Cells in a JNK-Dependent Manner
2014
Conformational Dynamics of Single G Protein-Coupled Receptors in Solution
2011 StandoutNobel
Making Structural Sense of Dimerization Interfaces of Delta Opioid Receptor Homodimers
2011
B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice
2021 StandoutNobel
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
Hydrogen Sulphide Induces μ Opioid Receptor-Dependent Analgesia in a Rodent Model of Visceral Pain
2010
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Trafficking of G Protein–Coupled Receptors
2006 StandoutNobel
Differential Response to Morphine of the Oligomeric State of μ-Opioid in the Presence of δ-Opioid Receptors
2011
Tools for GPCR drug discovery
2012
Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins
2017 StandoutNobel
Multiple Functions of Endocannabinoid Signaling in the Brain
2012
Works of Achla Gupta being referenced
Cell surface targeting of μ-δ opioid receptor heterodimers by RTP4
2008
Post-activation-mediated Changes in Opioid Receptors Detected by N-terminal Antibodies
2008
Conformation State-sensitive Antibodies to G-protein-coupled Receptors
2006
Interleukin‐6‐Mediated Autocrine Growth Promotion in Human Glioblastoma Multiforme Cell Line U87MG
1998
Regulation of an Opioid Receptor Chaperone Protein, RTP4, by Morphine
2018
Opioid Receptor Function Is Regulated by Post-endocytic Peptide Processing
2014
Potentiation of μ‐opioid receptor‐mediated signaling by ketamine
2011
AT1R–CB1R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II
2011
Monoclonal antibody to the δ opioid receptor acts as an agonist in dual regulation of adenylate cyclase in NG108‐15 cells
1999
G protein coupled receptor dimerization: implications in modulating receptor function
2001
Modulation of Opiate-Related Signaling Molecules in Morphine-Dependent Conditioned Behavior: Conditioned Place Preference to Morphine Induces CREB Phosphorylation
2009
Targeting opioid receptor heterodimers: Strategies for screening and drug development
2006
Novel endogenous peptide agonists of cannabinoid receptors
2009
Hemopressin is an inverse agonist of CB 1 cannabinoid receptors
2007
GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding
2013
A role for heterodimerization of μ and δ opiate receptors in enhancing morphine analgesia
2004
Increased Abundance of Opioid Receptor Heteromers After Chronic Morphine Administration
2010
Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake
2016