Standout Papers
Citation Impact
Citing Papers
Oncosome Formation in Prostate Cancer: Association with a Region of Frequent Chromosomal Deletion in Metastatic Disease
2009
Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions
2012 StandoutScienceNobel
The PAR complex regulates pulsed actomyosin contractions during amnioserosa apical constriction in Drosophila
2010
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Regulation of the Polarity Protein Par6 by TGFß Receptors Controls Epithelial Cell Plasticity
2005 Science
Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes
2018 StandoutScience
KRAS-dependent sorting of miRNA to exosomes
2015
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Identification of Double-stranded Genomic DNA Spanning All Chromosomes with Mutated KRAS and p53 DNA in the Serum Exosomes of Patients with Pancreatic Cancer
2014
Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters
2015
Oncogenic H-Ras Reprograms Madin-Darby Canine Kidney (MDCK) Cell-derived Exosomal Proteins Following Epithelial-Mesenchymal Transition
2013
Hallmarks of Cancer: The Next Generation
2011 Standout
The Impact of Oncogenic EGFRvIII on the Proteome of Extracellular Vesicles Released from Glioblastoma Cells
2018
Directional cell movement through tissues is controlled by exosome secretion
2015
Carcinoma‐associated fibroblasts: Non‐neoplastic tumour‐promoting mesenchymal cells
2013
Physiological functions of the HECT family of ubiquitin ligases
2009
Inhibition of Oncogenic Epidermal Growth Factor Receptor Kinase Triggers Release of Exosome-like Extracellular Vesicles and Impacts Their Phosphoprotein and DNA Content
2015
Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment
2015
In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior
2015
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Mechanobiology of YAP and TAZ in physiology and disease
2017
Deep Sequencing of RNA from Three Different Extracellular Vesicle (EV) Subtypes Released from the Human LIM1863 Colon Cancer Cell Line Uncovers Distinct Mirna-Enrichment Signatures
2014
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis
2016
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Wnt signaling in cancer
2016 Standout
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
Microglia and Wnt Pathways: Prospects for Inflammation in Alzheimer’s Disease
2020
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Natural Product-Like Macrocyclic N-Methyl-Peptide Inhibitors against a Ubiquitin Ligase Uncovered from a Ribosome-Expressed De Novo Library
2011
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
Design and Synthesis of a Homogeneous Erythropoietin Analogue with Two Human Complex‐Type Sialyloligosaccharides: Combined Use of Chemical and Bacterial Protein Expression Methods
2009 StandoutNobel
Different HECT domain ubiquitin ligases employ distinct mechanisms of polyubiquitin chain synthesis
2005
Complex networks orchestrate epithelial–mesenchymal transitions
2006 Standout
Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein
2010 StandoutNobel
Tumor metastasis: moving new biological insights into the clinic
2013
Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-β Pathways
2012
Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7
2010
Fibroblast-Derived Exosomes Contribute to Chemoresistance through Priming Cancer Stem Cells in Colorectal Cancer
2015
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy
2007 StandoutNobel
Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis
2014
Illuminating the metastatic process
2007
New Insights into the Regulation of Epithelial–Mesenchymal Transition and Tissue Fibrosis
2012
The E2 Ubiquitin-conjugating Enzymes Direct Polyubiquitination to Preferred Lysines
2010
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Exosome Transfer from Stromal to Breast Cancer Cells Regulates Therapy Resistance Pathways
2014
Structural organization of the tight junctions
2007
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
2009 StandoutNatureNobel
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Exosomes in tumor microenvironment influence cancer progression and metastasis
2013
EMT: 2016
2016 Standout
TGFβ in Cancer
2008 Standout
The Origin and Functions of Exosomes in Cancer
2018
Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
2016 Standout
Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization
2015
Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker
2007
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex
2009
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
An Expanded WW Domain Recognition Motif Revealed by the Interaction between Smad7 and the E3 Ubiquitin Ligase Smurf2
2006
Exosomes from Drug-Resistant Breast Cancer Cells Transmit Chemoresistance by a Horizontal Transfer of MicroRNAs
2014
RosettaDock in CAPRI rounds 6–12
2007 StandoutNobel
Post-transcriptional Wnt Signaling Governs Epididymal Sperm Maturation
2015
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication
2018 Standout
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Cullin Mediates Degradation of RhoA through Evolutionarily Conserved BTB Adaptors to Control Actin Cytoskeleton Structure and Cell Movement
2009
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Exosomes in Cancer Liquid Biopsy: A Focus on Breast Cancer
2017
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
Tumor microenvironment and cancer therapy resistance
2015
Biogenesis and function of extracellular vesicles in cancer
2018
Vesicle Trafficking and RNA Transfer Add Complexity and Connectivity to Cell–Cell Communication
2013
Focus on Extracellular Vesicles: New Frontiers of Cell-to-Cell Communication in Cancer
2016
Polyubiquitination by HECT E3s and the Determinants of Chain Type Specificity
2009
Extracellular vesicles: Exosomes, microvesicles, and friends
2013 Standout
Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal
2015 StandoutNobel
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Differential fates of biomolecules delivered to target cells via extracellular vesicles
2015
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Extracellular vesicles including exosomes are mediators of signal transduction: Are they protective or pathogenic?
2014
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Wnt proteins synergize to activate β-catenin signaling
2017
Mechanisms associated with biogenesis of exosomes in cancer
2019
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Metabolic reprogramming and cancer progression
2020 StandoutScience
Exosomes in developmental signalling
2016
Galectins: Multitask signaling molecules linking fibroblast, endothelial and immune cell programs in the tumor microenvironment
2018
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
2014 Standout
RHO GTPASES: Biochemistry and Biology
2005 Standout
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
Advances in the production of human therapeutic proteins in yeasts and filamentous fungi
2004
The Ubiquitin Code
2012 Standout
Structural Mechanisms Underlying Posttranslational Modification by Ubiquitin-Like Proteins
2007
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation
2011
Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited
2009
Breast Cancer‐Derived Exosomes Reflect the Cell‐of‐Origin Phenotype
2019
Structure and function of a HECT domain ubiquitin‐binding site
2011
Works of Abiodun A. Ogunjimi being referenced
Autoinhibition of the HECT-Type Ubiquitin Ligase Smurf2 through Its C2 Domain
2007
Switch Enhancers Interpret TGF-β and Hippo Signaling to Control Cell Fate in Human Embryonic Stem Cells
2013 Standout
The Ubiquitin Binding Region of the Smurf HECT Domain Facilitates Polyubiquitylation and Binding of Ubiquitylated Substrates
2009
Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration
2012
Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain
2005
Regulation of Cell Polarity and Protrusion Formation by Targeting RhoA for Degradation
2003 Science
High-level secretory expression of immunologically active intact antibody from the yeast Pichia pastoris
1999