Citation Impact
Citing Papers
CRISPR–Cas9 Structures and Mechanisms
2017 StandoutNobel
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Self-assembled mRNA vaccines
2021
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNatureNobel
HBV cccDNA: viral persistence reservoir and key obstacle for a cure of chronic hepatitis B
2015
Targeting Hepatitis B Virus With CRISPR/Cas9
2014
Systematic development of ionizable lipid nanoparticles for placental mRNA delivery using a design of experiments approach
2023 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
The Spring α-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action
2016 StandoutNobel
Preclinical and Clinical Advances of GalNAc-Decorated Nucleic Acid Therapeutics
2016
Digital PCR to assess gene-editing frequencies (GEF-dPCR) mediated by designer nucleases
2016
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Microbubbles in ultrasound-triggered drug and gene delivery
2008 Standout
Amino acid similarities and divergences in the small surface proteins of genotype C hepatitis B viruses between nucleos(t)ide analogue-naïve and lamivudine-treated patients with chronic hepatitis B
2013
A guide to genome engineering with programmable nucleases
2014 Standout
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Progress in the use of RNA interference as a therapy for chronic hepatitis B virus infection
2010
Modifications of mRNA vaccine structural elements for improving mRNA stability and translation efficiency
2021
Coordinated Activities of Human Dicer Domains in Regulatory RNA Processing
2012 StandoutNobel
Lipid nanoparticles for mRNA delivery
2021 Standout
Bacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral research and treatment
2015
Expanding the Biologist’s Toolkit with CRISPR-Cas9
2015 StandoutNobel
Harnessing the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated Cas9 system to disrupt the hepatitis B virus
2015
AAV-Mediated Delivery of Zinc Finger Nucleases Targeting Hepatitis B Virus Inhibits Active Replication
2014
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2020 Standout
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection
2018 StandoutNobel
TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP)
2017 StandoutNobel
Targeting hepatitis B virus cccDNA by CRISPR/Cas9 nuclease efficiently inhibits viral replication
2015
The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo
2014
Hepatitis B cure: From discovery to regulatory approval
2017
DNA cleavage enzymes for treatment of persistent viral infections: Recent advances and the pathway forward
2014
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
Off-target Effects in CRISPR/Cas9-mediated Genome Engineering
2015 Standout
RNA interference against viruses: strike and counterstrike
2007
LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
2021 StandoutNobel
Easy quantitative assessment of genome editing by sequence trace decomposition
2014 Standout
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
2010 StandoutNature
Therapeutic genome editing: prospects and challenges
2015
A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs
2008
Stable RNA interference rules for silencing
2013
Attacking hepatitis B virus cccDNA – The holy grail to hepatitis B cure
2016
mRNA vaccine with unmodified uridine induces robust type I interferon-dependent anti-tumor immunity in a melanoma model
2022 StandoutNobel
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Hydrodynamic Gene Delivery: Its Principles and Applications
2007
mRNA transcript therapy
2014 StandoutNobel
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNobel
Inhibition of HBV Expression in HBV Transgenic Mice Using AAV-Delivered CRISPR-SaCas9
2018
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA
2015 StandoutNobel
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA
2016 StandoutNobel
Refining strategies to translate genome editing to the clinic
2017
Genome-editing Technologies for Gene and Cell Therapy
2016
Genome Engineering with Targetable Nucleases
2014
EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection
2017 Standout
MicroRNA signatures in liver diseases
2009
Inhibition of hepatitis B virus by the CRISPR/Cas9 system via targeting the conserved regions of the viral genome
2015
Molecular Mechanisms of RNA Interference
2013 StandoutNobel
Seed Sequence-Matched Controls Reveal Limitations of Small Interfering RNA Knockdown in Functional and Structural Studies of Hepatitis C Virus NS5A-MOBKL1B Interaction
2014 StandoutNobel
Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus
2014 StandoutNobel
Biodistribution of Small Interfering RNA at the Organ and Cellular Levels after Lipid Nanoparticle-mediated Delivery
2011
The MicroRNA Spectrum in 12 Body Fluids
2010 Standout
RNA Interference-Mediated Silencing of the Respiratory Syncytial Virus Nucleocapsid Defines a Potent Antiviral Strategy
2009
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Targeted DNA Mutagenesis for the Cure of Chronic Viral Infections
2012
Works of Abdullah Ely being referenced
ssAAVs containing cassettes encoding SaCas9 and guides targeting hepatitis B virus inactivate replication of the virus in cultured cells
2017
Inhibition of hepatitis B virus replication in vivo using lipoplexes containing altritol-modified antiviral siRNAs
2010
Effective Inhibition of HBV Replication in Vivo by Anti-HBx Short Hairpin RNAs
2005
Exploiting the RNA interference pathway to counter hepatitis B virus replication
2005
Inactivation of Hepatitis B Virus Replication in Cultured Cells and In Vivo with Engineered Transcription Activator-Like Effector Nucleases
2013
Specific Inhibition of HBV Replication In Vitro and In Vivo With Expressed Long Hairpin RNA
2007
Expressed Anti-HBV Primary MicroRNA Shuttles Inhibit Viral Replication Efficiently In Vitro and In Vivo
2008
Progress With Developing Use of Gene Editing To Cure Chronic Infection With Hepatitis B Virus
2016
Inhibition of hepatitis B virus replication with linear DNA sequences expressing antiviral micro-RNA shuttles
2009
Efficient Inhibition of Hepatitis B Virus Replication In Vivo , Using Polyethylene Glycol-Modified Adenovirus Vectors
2008
A Convenient Method to Generate and Maintain Poly(A)-Encoding DNA Sequences Required for in Vitro Transcription of mRNA
2019
Progress and Prospects of Anti-HBV Gene Therapy Development
2015
EFFICIENT INHIBITION OF HEPATITIS B VIRUS REPLICATION IN VIVO USING PEG-MODIFIED ADENOVIRUS VECTORS
2008
Countering hepatitis B virus infection using RNAi: how far are we from the clinic?
2011