Citation Impact
Citing Papers
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
Combined MEK and BCL-2/XL Inhibition Is Effective in High-Grade Serous Ovarian Cancer Patient–Derived Xenograft Models and BIM Levels Are Predictive of Responsiveness
2019
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Intracellular Delivery System for Antibody–Peptide Drug Conjugates
2015 StandoutNobel
Engineering precision nanoparticles for drug delivery
2020 Standout
Loss in MCL-1 function sensitizes non-Hodgkin’s lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)
2015
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
A view on drug resistance in cancer
2019 StandoutNature
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Atropisomeric small molecule Bcl-2 ligands: Determination of bioactive conformation
2009
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
2012 Standout
Modular click chemistry libraries for functional screens using a diazotizing reagent
2019 StandoutNatureNobel
Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity
2020
Recent advances in the development of Mcl-1 inhibitors for cancer therapy
2019
Structural biology in fragment-based drug design
2010
Principles of early drug discovery
2010 Standout
From fragment to clinical candidate—a historical perspective
2009
Pharmacological targeting of the HIF hydroxylases – A new field in medicine development
2016 StandoutNobel
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Small-molecule Mcl-1 inhibitors: Emerging anti-tumor agents
2018
Targeting apoptosis in cancer therapy
2020 Standout
Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review
2018 Standout
Causes and consequences of microRNA dysregulation in cancer
2009 Standout
Palladium-catalyzed amidation–hydrolysis reaction of gem-dihaloolefins: efficient synthesis of homologated carboxamides from ketones
2009
The road less traveled: modulating signal transduction enzymes by inhibiting their protein–protein interactions
2009
Cancer and Radiation Therapy: Current Advances and Future Directions
2012 Standout
The multiple roles of computational chemistry in fragment-based drug design
2009
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
2013 Standout
BCL-2 family isoforms in apoptosis and cancer
2019 Standout
The rise of fragment-based drug discovery
2009
Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia
2015
The Role of HTS in Drug Discovery at the University of Michigan
2014
Mitochondria as multifaceted regulators of cell death
2019 Standout
Metal-catalysed approaches to amide bond formation
2011 Standout
Targeting the Bcl-2 family for cancer therapy
2012
Small molecule Mcl-1 inhibitors for the treatment of cancer
2014
Enhancements of screening collections to address areas of unmet medical need: an industry perspective
2010
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics
2009
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Impact of high-throughput screening in biomedical research
2011 Standout
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
Contribution of Organofluorine Compounds to Pharmaceuticals
2020 Standout
Harnessing the ambiphilicity of silyl nitronates in a catalytic asymmetric approach to aliphatic β3-amino acids
2021 StandoutNobel
Accelerating Effect of Triazolyl and Related Heteroaryl Substituents on SNAr Reactions: Evidence of Hydrogen-Bond Stabilized Transition States
2015
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations
2018
Characterization of Peptide Aptamers Targeting Bfl-1 Anti-Apoptotic Protein
2011
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
Organocatalyzed Trifluoromethylation of Ketones and Sulfonyl Fluorides by Fluoroform under a Superbase System
2015
Preparation of One-Carbon Homologated Amides from Aldehydes or Primary Alcohols
2014
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Recent advances in the trifluoromethylation methodology and new CF3-containing drugs
2014
Molecular Docking and Structure-Based Drug Design Strategies
2015 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Copper-catalyzed trifluoromethylation of arylsulfinate salts using an electrophilic trifluoromethylation reagent
2013
New dimension in therapeutic targeting of BCL-2 family proteins
2015
Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents
2014 Standout
Regioselective Synthesis of Pyrazole Triflones Based on Triflyl Alkyne Cycloadditions
2012
Rational Combinations Using HDAC Inhibitors
2009
Nanoparticle-Mediated Co-Delivery of Notch-1 Antibodies and ABT-737 as a Potent Treatment Strategy for Triple-Negative Breast Cancer
2020
Direct activation of full-length proapoptotic BAK
2013
Synthetic Methods for Compounds Having CF3–S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions
2014
Mechanism and Scope of Base‐Controlled Catalyst‐Free N‐Arylation of Amines with Unactivated Fluorobenzenes
2016 StandoutNobel
Solubility Advantage of Amorphous Drugs and Pharmaceutical Cocrystals
2011 Standout
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Assessing Atropisomer Axial Chirality in Drug Discovery and Development
2011 Standout
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Beyond the Rule of 5: Lessons Learned from AbbVie’s Drugs and Compound Collection
2017
An architectonic macrolide library based on a C2-symmetric macrodiolide toward pharmaceutical compositions
2015 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Iron-catalyzed ketonization of 2-aryl-1,1-dibromoalkenes with KOAc: Synthesis of α-acetoxy aryl ketones via a Michael-like addition process
2011
Improving Drug Design: An Update on Recent Applications of Efficiency Metrics, Strategies for Replacing Problematic Elements, and Compounds in Nontraditional Drug Space
2016
Stereoselective Amine Addition to Six‐Membered Cyclic Nitronates Promoted by Silyl Triflate
2013
Direct control of mitochondrial function by mTOR
2009
Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
2012 Standout
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Evaluation of Diverse α/β-Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 Domain
2011
Works of Aaron Kunzer being referenced
Discovery of a novel small molecule binding site of human survivin
2007
Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein
2014
Rapid, robust, clean, catalyst-free synthesis of 2-halo-3-carboxyindoles
2011
Ortho selectivity in SNAr substitutions of 2,4-dihaloaromatic compounds. Reactions with piperidine
2009
Discovery of an Orally Bioavailable Small Molecule Inhibitor of Prosurvival B-Cell Lymphoma 2 Proteins
2008
A Facile One-Carbon Homologation of Aryl Aldehydes to Amides
2002