Citation Impact
Citing Papers
Randomized Controlled Trial of Annual Zoledronic Acid to Prevent Gonadotropin-Releasing Hormone Agonist–Induced Bone Loss in Men With Prostate Cancer
2007
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
2011 Standout
IL-1 Blockade in Autoinflammatory Syndromes
2014
Why not treat human cancer with interleukin-1 blockade?
2010
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge
2017 StandoutNobel
Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation
2014
Necroptosis and its role in inflammation
2015 StandoutNature
Canakinumab for the treatment of acute flares in difficult‐to‐treat gouty arthritis: Results of a multicenter, phase II, dose‐ranging study
2010
Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double-blind, randomised study
2011
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
2011 Standout
Canakinumab for acute gouty arthritis in patients with limited treatment options: results from two randomised, multicentre, active-controlled, double-blind trials and their initial extensions
2012
Emerging inflammasome effector mechanisms
2011
Autoinflammatory Disease Reloaded: A Clinical Perspective
2010 Standout
Redox distress and genetic defects conspire in systemic autoinflammatory diseases
2015
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Zoledronic Acid and Clinical Fractures and Mortality after Hip Fracture
2007
Activation and regulation of the inflammasomes
2013 Standout
Improving de novo protein binder design with deep learning
2023 StandoutNobel
Development trends for human monoclonal antibody therapeutics
2010
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β
2009
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease
2014 Standout
Sensors of the innate immune system: their link to rheumatic diseases
2010 StandoutNobel
Inflammasome and IL-1β-Mediated Disorders
2010
Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer
2017 StandoutNobel
IL-1 pathways in inflammation and human diseases
2010
Caspase Functions in Cell Death and Disease
2013 Standout
Gout
2016 Standout
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
2010 Standout
Systemic amyloidosis
2015 Standout
The IL-1 family: regulators of immunity
2010
The immunology of stroke: from mechanisms to translation
2011 Standout
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2010
2011 Standout
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
2016 StandoutNature
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Monogenic IL-1 mediated autoinflammatory and immunodeficiency syndromes: Finding the right balance in response to danger signals
2010
Functional mapping and annotation of genetic associations with FUMA
2017 Standout
The immune contexture in human tumours: impact on clinical outcome
2012 Standout
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
Sterile inflammation: sensing and reacting to damage
2010 Standout
Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer
2010 Standout
Blockade of interleukin 1 in type 1 diabetes mellitus
2010
The Inflammasomes
2010 Standout
Mechanisms and Functions of Inflammasomes
2014 Standout
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
2012
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
2014
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
Regulation of inflammasome activity
2010
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
2015 Standout
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Mortality Risk Associated With Low-Trauma Osteoporotic Fracture and Subsequent Fracture in Men and Women
2009 Standout
Monogenic autoinflammatory diseases: new insights into clinical aspects and pathogenesis
2010
Role of IL-1β in type 2 diabetes
2010
Inflammasomes in health and disease
2012 StandoutNature
Autoinflammation: The prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses
2009
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
2016 Standout
Canakinumab relieves symptoms of acute flares and improves health-related quality of life in patients with difficult-to-treat Gouty Arthritis by suppressing inflammation: results of a randomized, dose-ranging study
2011
IL‐1: Discoveries, controversies and future directions
2010
In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes
2009
Current concepts in the diagnosis and management of cytokine release syndrome
2014 Standout
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer
2011
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Neurologic manifestations of the cryopyrin-associated periodic syndrome
2010
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
2011 StandoutNobel
Intracellular sensing of microbes and danger signals by the inflammasomes
2011
Gout
2021 Standout
Inflammasomes and Their Roles in Health and Disease
2012
AB1115 A novel mutation in the CIAS1/NLRP3 gene associated with an unexpected phenotype of caps
2012
Interleukin-1 (IL-1) Pathway
2010
Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice
2017 StandoutNobel
Physiology of Microglia
2011 Standout
Works of A. Widmer being referenced
Two-year results from an open-label, multicentre, phase III study evaluating the safety and efficacy of canakinumab in patients with cryopyrin-associated periodic syndrome across different severity phenotypes
2011
Efficacy and safety of the human anti-IL-1beta monoclonal antibody canakinumab in rheumatoid arthritis: results of a 12-week, phase II, dose-finding study
2011
Use of Canakinumab in the Cryopyrin-Associated Periodic Syndrome
2009
Intravenous Zoledronic Acid in Postmenopausal Women With Low Bone Mineral Density
2003