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Citing Papers
A cyclic oligonucleotide signaling pathway in type III CRISPR-Cas systems
2017 Science
Isolation of the human peroxisome proliferator activated receptor gamma cDNA: expression in hematopoietic cells and chromosomal mapping.
1995
Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression
1996
Coordinate Regulation of the Expression of the Fatty Acid Transport Protein and Acyl-CoA Synthetase Genes by PPARα and PPARγ Activators
1997
PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene.
1996
Induction of the Acyl-Coenzyme A Synthetase Gene by Fibrates and Fatty Acids Is Mediated by a Peroxisome Proliferator Response Element in the C Promoter
1995
Cleavage of 5′ splice site and lariat formation are independent of 3′ splice site in yeast mRNA splicing
1985 StandoutNatureNobel
Receptor protein tyrosine phosphatase α activates Src-family kinases and controls integrin-mediated responses in fibroblasts
1999
Correlation between expression of peroxisome proliferator-activated receptor β and squamous differentiation in epidermal and tracheobronchial epithelial cells
1999
Perforin-independent β-cell destruction by diabetogenic CD8+ T lymphocytes in transgenic nonobese diabetic mice
1999
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
1998 StandoutNature
Dynamics of fat cell turnover in humans
2008 StandoutNature
Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
1988 StandoutNature
PPARδ Is an APC-Regulated Target of Nonsteroidal Anti-Inflammatory Drugs
1999
The Human Peroxisome Proliferator-activated Receptor (PPAR) Subtype NUC1 Represses the Activation of hPPARα and Thyroid Hormone Receptors
1995
cDNA cloning and characterization of the transcriptional activities of the hamster peroxisome proliferator-activated receptor haPPARγ
1995
Expression of the Peroxisome Proliferator-activated Receptor α Gene Is Stimulated by Stress and Follows a Diurnal Rhythm
1996
Xenopus peroxisome proliferator activated receptors: Genomic organization, response element recognition, heterodimer formation with retinoid X receptor and activation by fatty acids
1993
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Identification, Characterization, and Tissue Distribution of Human Peroxisome Proliferator-activated Receptor (PPAR) Isoforms PPARγ2 versus PPARγ1 and Activation with Retinoid X Receptor Agonists and Antagonists
1997
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
2001 StandoutNature
Peroxisome Proliferator-activated Receptor α Activation Modulates Cellular Redox Status, Represses Nuclear Factor-κB Signaling, and Reduces Inflammatory Cytokine Production in Aging
1998
Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study
2017 Standout
Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators
1994
The 2–5 A system: Modulation of viral and cellular processes through acceleration of RNA degradation
1998
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
1994 StandoutNobel
PPAR Tissue Distribution and Interactions with Other Hormone‐Signaling Pathwaysa
1996
cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor
1993
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
1991 StandoutNature
New advances in our understanding of the “unique” RNase L in host pathogen interaction and immune signaling
2016
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Phosphorothioate analogs of 2',5'-oligoadenylate. Enzymatically synthesized 2',5'-phosphorothioate dimer and trimer: unequivocal structural assignment and activation of 2',5'-oligoadenylate-dependent endoribonuclease
1987 StandoutNobel
Peroxisome proliferator-activated receptors A link between endocrinology and nutrition?
1993
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
1998 StandoutNature
Peroxisome proliferator-activated receptor alpha: role in rodent liver cancer and species differences
1999
Positive regulation of the peroxisomal β‐oxidation pathway by fatty acids through activation of peroxisome proliferator‐activated receptors (PPAR)
1993
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Exon mutations uncouple 5′ splice site selection from U1 snRNA pairing
1990 StandoutNobel
Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques
1989 StandoutNobel
Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor.
1995
Differential Expression of Peroxisome Proliferator-Activated Receptor Subtypes During the Differentiation of Human Keratinocytes
1998
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
1999 StandoutNature
Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay
1997
A Carboxyl-terminal Extension of the Zinc Finger Domain Contributes to the Specificity and Polarity of Peroxisome Proliferator-activated Receptor DNA Binding
1998
Evidence for Transcriptional Induction of the Liver Fatty-Acid-Binding-Protein Gene by Bezafibrate in the Small Intestine
1995
Bisphosphonates Act Directly on the Osteoclast to Induce Caspase Cleavage of Mst1 Kinase during Apoptosis
1999
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
1998 StandoutNature
Cooperative Formation of Higher Order Peroxisome Proliferator-activated Receptor and Retinoid X Receptor Complexes on the Peroxisome Proliferator Responsive Element of the Rat Hydratase-Dehydrogenase Gene
1995
Skeletal muscle peroxisome proliferator- activated receptor-gamma expression in obesity and non- insulin-dependent diabetes mellitus.
1998
Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.
1996
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Identification of an extended half‐site motif required for the function of peroxisome proliferator‐activated receptor α
1997
The PPARα–leukotriene B4 pathway to inflammation control
1996 Nature
Peroxisome proliferator-activated receptor agonists
1997
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
2004 StandoutNature
The hormone resistin links obesity to diabetes
2001 StandoutNature
Negative regulation of peroxisome proliferator-activated receptor-gamma gene expression contributes to the antiadipogenic effects of tumor necrosis factor-alpha.
1996
2- and 8-Azido photoaffinity probes. 1. Enzymic synthesis, characterization and biological properties of 2- and 8-azido photoprobes of 2-5A and photolabeling of 2-5A binding proteins
1988 StandoutNobel
Novel Sequence Determinants in Peroxisome Proliferator Signaling
1995
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Chromosomal Localisation, Inducibility, Tissue‐Specific Expression and Strain Differences in Three Murine Peroxisome‐Proliferator‐Activated‐Receptor Genes
1995
Peroxisome Proliferator-Activated Receptor-alpha and the Pleiotropic Responses to Peroxisome Proliferators
1998
The RXR heterodimers and orphan receptors
1995 Standout
Structural requirements and cell-type specificity for ligand activation of peroxisome proliferator-activated receptors
1997
Identification of peroxisome proliferator-activated receptor ligands from a biased chemical library
1997
Peroxisome proliferator-activated receptors: finding the orphan a home
1994
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
1994 Standout
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR7 and RXRa
1994
Cloning of a Protein That Mediates Transcriptional Effects of Fatty Acids in Preadipocytes
1995
Roles of PPARs in health and disease
2000 StandoutNature
Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors
1999
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
2008 StandoutNature
Alternative branch points are selected during splicing of a yeast pre-mRNA in mammalian and yeast extracts.
1986 StandoutNobel
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome proliferator-mediated signaling.
1993
A Very Large Metallosupramolecular Capsule with Cube-like 43 Topology Assembled from Twelve Cu(II) Centers and Eight Tri-Bidentate Tri-Anionic Ligands Derived from 2,4,6-Triphenylazo-1,3,5-trihydroxybenzene
1999 StandoutNobel
GERM-LINE TRANSFORMATION OF MICE
1986
Induction of ppp(A2'p)nA-dependent RNase in murine JLS-V9R cells during growth inhibition.
1983
Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver.
1993
Mechanism of interferon action. Purification and substrate specificities of the double-stranded RNA-dependent protein kinase from untreated and interferon-treated mouse fibroblasts.
1985
Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes
2002 StandoutScience
2',5'-Oligoadenylates chiral at phosphorus: enzymic synthesis, properties, and biological activities of 2',5'-phosphorothioate trimer and tetramer analogs synthesized from (SP)-ATP.alpha.S
1985
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
2018 StandoutScience
Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element.
1994
2-5A synthetase: assay, distribution and variation with growth or hormone status
1979 Nature
Regulation of Adipose Cell Number in Man
1997
Expression in transgenic mice of class I histocompatibility antigens controlled by the metallothionein promoter.
1989 StandoutNobel
Bone Resorption by Osteoclasts
2000 StandoutScience
The murine 2-5A synthetase locus: three distinct transcripts from two linked genes
1991
Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription
1995
Biological activities of phosphodiester linkage isomers of 2-5A.
1983
Autocrine β-related interferon controls c-myc suppression and growth arrest during hematopoietic cell differentiation
1986
Functional Role of Type I and Type II Interferons in Antiviral Defense
1994 StandoutScience
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS: A Nuclear Receptor Signaling Pathway in Lipid Physiology
1996
Increased nuclease activity in cells treated with pppA2'p5'A2'p5' A.
1979 StandoutNobel
Diverse peroxisome proliferator-activated receptors bind to the peroxisome proliferator-responsive elements of the rat hydratase/dehydrogenase and fatty acyl-CoA oxidase genes but differentially induce expression.
1993
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
High-frequency germ-line transmission of plasmid DNA sequences injected into fertilized zebrafish eggs.
1991 StandoutNobel
The (2′‐5′)Oligoadenylate (pppA2′‐5′A2′‐5′A) Synthetase and Protein Kinase(s) from Interferon‐Treated Cells
1979
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
Differential activation of adipogenesis by multiple PPAR isoforms.
1996
Differential Expression of Peroxisome Proliferator-Activated Receptor-α, -β, and -γ during Rat Embryonic Development*
1998
Analogs of (A2'p)nA. Correlation of structure of analogs of ppp(A2'p)2A and (A2'p)2A with stability and biological activity.
1982
Integrin Signaling
1999 StandoutScience
Synthesis in E. coli of a polypeptide with human leukocyte interferon activity
1980 Nature
Interactions between double-stranded RNA regulators and the protein kinase DAI.
1992
Synthesis and characterization of (2′-5′)ppp3′dA(p3′dA)n, an analogue of (2′-5′)pppA(pA)n
1981 Nature
Evidence for Transcriptional Induction of the Liver Fatty‐Acid‐Binding‐Protein Gene by Bezafibrate in the Small Intestine
1995
Interactions between Double-Stranded RNA Regulators and the Protein Kinase DAI
1992
Four different forms of interferon-induced 2',5'-oligo(A) synthetase identified by immunoblotting in human cells.
1987
Bile Acids: Natural Ligands for an Orphan Nuclear Receptor
1999 StandoutScience
Liver Regeneration
1997 StandoutScience
CELLULAR RESPONSES TO INTERFERON-γ
1997 Standout
Induction of pulmonary indoleamine 2,3-dioxygenase by interferon.
1981
Peroxisome Proliferator Activated Receptor-α Expression in Human Liver
1998
Heterogeneous nuclear RNA promotes synthesis of (2',5')oligoadenylate and is cleaved by the (2',5')oligoadenylate-activated endoribonuclease.
1982
Peroxisome proliferator activated receptor-alpha expression in human liver.
1998
(2??5?) Oligoadenylate synthetase in the maturation of rabbit reticulocytes
1984
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
2002 StandoutNobel
Ribosomal RNA cleavage, nuclease activation and 2-5A (ppp(A2′p)nA) in interferon-treated cells
1981
Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function.
1995
Effect of Interferon-α1 from E. coli on Some Cell Functions
1980 StandoutScienceNobel
An RNA Processing Activity That Debranches RNA Lariats
1985 Science
Do Peroxisome Proliferating Compounds Pose a Hepatocarcinogenic Hazard to Humans?
1998
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*
1999 Standout
Regulation of the peroxisome proliferator-activated receptor alpha gene by glucocorticoids.
1994
Targeted Disruption of the α Isoform of the Peroxisome Proliferator-Activated Receptor Gene in Mice Results in Abolishment of the Pleiotropic Effects of Peroxisome Proliferators
1995
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.
1994
IFN-α Directly Promotes Programmed Cell Death-1 Transcription and Limits the Duration of T Cell-Mediated Immunity
2011 StandoutNobel
(2'-5')Oligoadenylate in rat liver: modulation after partial hepatectomy.
1983
RNA splicing and intron turnover are greatly diminished by a mutant yeast branch point.
1986 StandoutNobel
Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.
1986
Transactivation of the peroxisome proliferator-activated receptor is differentially modulated by hepatocyte nuclear factor-4.
1994
Identification of a Nuclear Receptor for Bile Acids
1999 StandoutScience
Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults--The Evidence Report. National Institutes of Health.
1998 Standout
Conditional ectopic expression of C/EBP beta in NIH-3T3 cells induces PPAR gamma and stimulates adipogenesis.
1995
Works of A. Schmidt being referenced
Interferon action: Isolation of Nuclease F, A translation inhibitor activated by interferon‐induced (2′–5′) oligo‐isoadenylate
1978
Differentiation of a human monocyte-like cell line by (2′–5′) oligoisoadenylate
1984
Protein-tyrosine phosphatase activity regulates osteoclast formation and function: inhibition by alendronate.
1996
Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids
1992
An interferon-induced phosphodiesterase degrading (2'-5') oligoisoadenylate and the C-C-A terminus of tRNA.
1979
A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity.
1994
Isolation of two interferon-induced translational inhibitors: a protein kinase and an oligo-isoadenylate synthetase.
1978
The interferon-induced protein kinase PK-i from mouse L cells.
1979
Developmental and tissue-specific expression directed by the alpha 2 type I collagen promoter in transgenic mice.
1986
Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids.
1992
[20] Interferon-induced enzymes: Microassays and their applications; purification and assay of (2′-5′)-oligoadenylate synthetase and assay of 2′-phosphodiesterase
1981
Kinetics of the induction of three translation-regulatory enzymes by interferon.
1979
ROLE OF INTERFERON‐INDUCED ENZYMES IN THE ANTIVIRAL AND ANTIMITOGENIC EFFECTS OF INTERFERON
1980