Citation Impact
Citing Papers
Human Immunodeficiency Virus Type 2 (HIV-2)/HIV-1 Envelope Chimeras Detect High Titers of Broadly Reactive HIV-1 V3-Specific Antibodies in Human Plasma
2008
Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium
2017
Cytoplasmic ATP Hydrolysis Powers Transport of Lipopolysaccharide Across the Periplasm in E. coli
2012 Science
Evidence for the Assembly of a Bacterial Tripartite Multidrug Pump with a Stoichiometry of 3:6:3
2011
MacB ABC Transporter Is a Dimer Whose ATPase Activity and Macrolide-binding Capacity Are Regulated by the Membrane Fusion Protein MacA
2008
Multidrug binding properties of the AcrB efflux pump characterized by molecular dynamics simulations
2012
Structure and Mechanism of RND‐Type Multidrug Efflux Pumps
2011
Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters
2017
Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket
2011 Nature
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives
2016
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
2021 StandoutNobel
Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump
2018
Crucial Role of Asp408 in the Proton Translocation Pathway of Multidrug Transporter AcrB: Evidence from Site-Directed Mutagenesis and Carbodiimide Labeling
2009
Contact‐dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB
2008
Structure of the AcrAB–TolC multidrug efflux pump
2014 Nature
Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB
2016
AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity
2015
Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB
2014
AcrB: a mean, keen, drug efflux machine
2019
Stable RAGE-Heparan Sulfate Complexes Are Essential for Signal Transduction
2013
Crystal structure of AcrB complexed with linezolid at 3.5 Å resolution
2013
Switch-Loop Flexibility Affects Transport of Large Drugs by the Promiscuous AcrB Multidrug Efflux Transporter
2014
The assembled structure of a complete tripartite bacterial multidrug efflux pump
2009
Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors
2006
Conserved small protein associates with the multidrug efflux pump AcrB and differentially affects antibiotic resistance
2012
Clinically Relevant Chromosomally Encoded Multidrug Resistance Efflux Pumps in Bacteria
2006
New insights into the structural and functional involvement of the gate loop in AcrB export activity
2017
Some Ligands Enhance the Efflux of Other Ligands by the Escherichia coli Multidrug Pump AcrB
2013
De novo design of immunoglobulin-like domains
2022 StandoutNobel
Drug transport mechanism of the AcrB efflux pump
2009
Signal Transduction in Receptor for Advanced Glycation End Products (RAGE)
2011
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop
2012
Modeling the Interaction between Quinolinate and the Receptor for Advanced Glycation End Products (RAGE): Relevance for Early Neuropathological Processes
2015
The molecular hallmarks of epigenetic control
2016 Standout
Aromatic Rings in Chemical and Biological Recognition: Energetics and Structures
2011
The mechanisms of Hedgehog signalling and its roles in development and disease
2013 Standout
Molecular mechanisms of antibiotic resistance
2014 Standout
EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics
2014 StandoutNobel
Interaction of the S100A6 mutant (C3S) with the V domain of the receptor for advanced glycation end products (RAGE)
2013
Electron Sharing and Anion–π Recognition in Molecular Triangular Prisms
2013 StandoutNobel
Advanced Glycation End Product Recognition by the Receptor for AGEs
2011
Engineered proteins with desired specificity: DARPins, other alternative scaffolds and bispecific IgGs
2014
Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii
2017
The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
2017 Standout
Dissection of Mechanistic Principles of a Secondary Multidrug Efflux Protein
2012
An artificial molecular pump
2015 StandoutNobel
Two β-strands of RAGE participate in the recognition and transport of amyloid-β peptide across the blood brain barrier
2013
Intrinsic antibiotic resistance: Mechanisms, origins, challenges and solutions
2013
Structurally Mapping Endogenous Heme in the CcmCDE Membrane Complex for Cytochrome c Biogenesis
2018 StandoutNobel
The Science of Antibiotic Discovery
2020 Standout
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Neurovascular Dysfunction and Faulty Amyloid -Peptide Clearance in Alzheimer Disease
2012
A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease
2012
Role of the polycomb protein EED in the propagation of repressive histone marks
2009 Nature
Waltzing transporters and 'the dance macabre' between humans and bacteria
2006
Crystal Structures of the Choline/Acetylcholine Substrate-binding Protein ChoX from Sinorhizobium meliloti in the Liganded and Unliganded-Closed States
2008
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
Substrate-bound structure of the E. coli multidrug resistance transporter MdfA
2015
The ABC-F protein EttA gates ribosome entry into the translation elongation cycle
2014 StandoutNobel
Quantification of Cation–π Interactions in Protein–Ligand Complexes: Crystal‐Structure Analysis of Factor Xa Bound to a Quaternary Ammonium Ion Ligand
2005
RND Efflux Pumps: Structural Information Translated into Function and Inhibition Mechanisms
2013
Change in the Molecular Dimension of a RAGE-Ligand Complex Triggers RAGE Signaling
2016
Illumination of growth, division and secretion by metabolic labeling of the bacterial cell surface
2015 StandoutNobel
Protein engineering methods applied to membrane protein targets
2012
Structural basis of RND-type multidrug exporters
2015
Membrane protein structural bioinformatics
2011
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
Structures of membrane proteins
2010 StandoutNobel
An allosteric modulator to control endogenous G protein-coupled receptors with light
2014
Regulation of type I interferon responses
2013 Standout
Secretion systems in Gram-negative bacteria: structural and mechanistic insights
2015
Molecular Gauge Blocks for Building on the Nanoscale
2012 StandoutNobel
De novo design of buttressed loops for sculpting protein functions
2024 StandoutNobel
Crystal Structure of the Neisseria gonorrhoeae MtrD Inner Membrane Multidrug Efflux Pump
2014
Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications
2011
Heterologous Epitope-Scaffold Prime∶Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant
2011 StandoutNobel
Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli
2011 Nature
Recent achievements in developing the biocatalytic toolbox for chiral amine synthesis
2014
Small Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal Transduction
2016
Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump
2017
Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-β Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus
2016
The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins
2016
Orthogonal photoswitching in a multifunctional molecular system
2016 StandoutNobel
Structural Insights into Calcium-Bound S100P and the V Domain of the RAGE Complex
2014
Receptor for Advanced Glycation End Products (RAGE) Functions as Receptor for Specific Sulfated Glycosaminoglycans, and Anti-RAGE Antibody or Sulfated Glycosaminoglycans Delivered in Vivo Inhibit Pulmonary Metastasis of Tumor Cells
2012
Molecular mechanisms of antibiotic resistance
2011
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs
2014
Efflux-mediated antimicrobial resistance
2005
Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa
2015
Antibacterial drug discovery in the resistance era
2016 StandoutNature
Targeting of RAGE-ligand signaling impairs breast cancer cell invasion and metastasis
2016
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Multidrug efflux pumps: structure, function and regulation
2018 Standout
Recent advances in Sonogashira reactions
2011 Standout
A Membrane Burial Potential with H-Bonds and Applications to Curved Membranes and Fast Simulations
2018 StandoutNobel
ABC transporter‐mediated release of a haem chaperone allows cytochrome c biogenesis
2006
Acinetobacter baumannii : Emergence of a Successful Pathogen
2008 Standout
Design and Synthesis of Nonequilibrium Systems
2015 StandoutNobel
Anticalins: Exploiting a non‐Ig scaffold with hypervariable loops for the engineering of binding proteins
2013
Total synthesis, stereochemical elucidation and biological evaluation of Ac2SGL; a 1,3-methyl branched sulfoglycolipid from Mycobacterium tuberculosis
2012
Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump
2013
The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs
2014
Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective
2017 Standout
Bidirectional Photomodulation of Surface Tension in Langmuir Films
2016 StandoutNobel
Engineered Biosynthesis of β‐Alkyl Tryptophan Analogues
2018 StandoutNobel
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
Clinical Implications of Extracellular HMGA1 in Breast Cancer
2019
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Multidrug Resistance in Bacteria
2009
Metabolic Compensation of Fitness Costs Is a General Outcome for Antibiotic-Resistant Pseudomonas aeruginosa Mutants Overexpressing Efflux Pumps
2017
Structure and Operation of Bacterial Tripartite Pumps
2013
Synthesis of Optically Active β- or γ-Alkyl-Substituted Alcohols through Copper-Catalyzed Asymmetric Allylic Alkylation with Organolithium Reagents
2013 StandoutNobel
Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems
2008
Folding of Oligoviologens Induced by Radical–Radical Interactions
2014 StandoutNobel
An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump
2017
Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template
2012 StandoutNobel
Aromatische Ringe in chemischer und biologischer Erkennung: Energien und Strukturen
2011
Direct and Versatile Synthesis of Red‐Shifted Azobenzenes
2016 StandoutNobel
DAMP-sensing receptors in sterile inflammation and inflammatory diseases
2019 Standout
Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective
2010 Standout
Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products
2013
The Immune Response in Tuberculosis
2013 Standout
Is RAGE Still A Therapeutic Target For Alzheimer’s Disease?
2012
HMGB1 conveys immunosuppressive characteristics on regulatory and conventional T cells
2012
Monobodies and other synthetic binding proteins for expanding protein science
2017
Beyond Antibodies as Binding Partners: The Role of Antibody Mimetics in Bioanalysis
2017
A Roadmap to Success in Photopharmacology
2015
Different Functions of MdtB and MdtC Subunits in the Heterotrimeric Efflux Transporter MdtB2C Complex ofEscherichia coli
2012
Enzymatic asymmetric synthesis of chiral amino acids
2018
Synthesis of Immunostimulatory α-C-Galactosylceramide Glycolipids via Sonogashira Coupling, Asymmetric Epoxidation, and Trichloroacetimidate-Mediated Epoxide Opening
2010
Emerging Targets in Photopharmacology
2016 StandoutNobel
The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria
2015
Origins and Evolution of Antibiotic Resistance
2010 Standout
Protein labeling for live cell fluorescence microscopy with a highly photostable renewable signal
2017
A coordinated network of transporters with overlapping specificities provides a robust survival strategy
2009
The crystal structure of MexR from Pseudomonas aeruginosa in complex with its antirepressor ArmR
2008
Asymmetric Enzymatic Synthesis of Allylic Amines: A Sigmatropic Rearrangement Strategy
2016 StandoutNobel
MacAB Is Involved in the Secretion ofEscherichia coliHeat-Stable Enterotoxin II
2008
Unraveling the Photoswitching Mechanism in Donor–Acceptor Stenhouse Adducts
2016 StandoutNobel
Targeting RAGE Signaling in Inflammatory Disease
2017
Divergent Evolution of Function in the ROK Sugar Kinase Superfamily: Role of Enzyme Loops in Substrate Specificity
2007
Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer
2018 Standout
Red-Shifting Azobenzene Photoswitches for in Vivo Use
2015 Standout
Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins
2017 StandoutNobel
Works of A. Schiefner being referenced
CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans
2011
Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism
2006 Science
A Photoswitchable Neurotransmitter Analogue Bound to Its Receptor
2013
Cation-π Interactions as Determinants for Binding of the Compatible Solutes Glycine Betaine and Proline Betaine by the Periplasmic Ligand-binding Protein ProX from Escherichia coli
2004
Structural Basis for the Binding of Compatible Solutes by ProX from the Hyperthermophilic Archaeon Archaeoglobus fulgidus
2004
The AcrB Efflux Pump: Conformational Cycling and Peristalsis Lead to Multidrug Resistance
2008
Structural Evaluation of Potent NKT Cell Agonists: Implications for Design of Novel Stimulatory Ligands
2009
Structural and biochemical analyses reveal a monomeric state of the bacterial lipocalin Blc
2010
Crystal structure of the ω‐aminotransferase from Paracoccus denitrificans and its phylogenetic relationship with other class III amino‐ transferases that have biotechnological potential
2013
Crystallographic analysis of AcrB
2004
Structural Basis for Ligand Recognition and Activation of RAGE
2010
Crystallization and preliminary X-ray analysis of the trehalose/maltose ABC transporter MalFGK2fromThermococcus litoralis
2002
Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 Neutralization
2007
Combinatorial Design of an Anticalin Directed against the Extra-Domain B for the Specific Targeting of Oncofetal Fibronectin
2012
The Crystal Structure of Mlc, a Global Regulator of Sugar Metabolism in Escherichia coli
2005
The Menagerie of Human Lipocalins: A Natural Protein Scaffold for Molecular Recognition of Physiological Compounds
2015