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Citing Papers
Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells
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The × Gene of Hepatitis B Virus Induced Growth Stimulation and Tumorigenic Transformation of Mouse NIH3T3 Cells
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Amino Acid Variants in the Human Leptin Receptor: Lack of Association to Juvenile Onset Obesity
1997
Acute stimulation of glucose metabolism in mice by leptin treatment
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Hyperleptinemia of Pregnancy Associated with the Appearance of a Circulating Form of the Leptin Receptor
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A 9 Å Resolution X-Ray Crystallographic Map of the Large Ribosomal Subunit
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Identification of targets of leptin action in rat hypothalamus.
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Demonstration of a Leptin Binding Factor in Human Serum
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Receptor-mediated regional sympathetic nerve activation by leptin.
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Absence of Soluble Leptin Receptor in Plasma fromdbPas/dbPas and Otherdb/db Mice
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Recognition of Gram-negative bacteria and endotoxin by the innate immune system
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The Protein Data Bank
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Leptin increases serotonin turnover by inhibition of brain nitric oxide synthesis
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Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice
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Relatively low plasma leptin concentrations precede weight gain in Pima Indians
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Leptin enters the brain by a saturable system independent of insulin
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Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma.
1996
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism
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Localization of leptin receptor mRNA and the long form splice variant (Ob‐Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization
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Leptin: a review of its peripheral actions and interactions
2002
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Recognition of Bacterial Endotoxins by Receptor-Dependent Mechanisms
1993
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Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene
1997
THE MOLECULAR BIOLOGY OF HEPATITIS DELTA VIRUS
1995
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1998
Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice
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Leptin's Actions on the Reproductive Axis: Perspectives and Mechanisms
1999
Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-κB activation in endothelial cells
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1997
A human leptin mutant induces weight gain in normal mice
1997
Pathophysiological Significance of theObeseGene Product, Leptin, in Ventromedial Hypothalamus (VMH)-Lesioned Rats: Evidence for Loss of Its Satiety Effect in VMH-Lesioned Rats1
1997
Leptin and inflammation-associated cachexia in chronic kidney disease
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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
1994 StandoutNature
CD4: Collaborator in immune recognition and HIV infection
1990 StandoutNobel
The arcuate nucleus as a primary site of satiety effect of leptin in rats
1997
Polygenic control of Caenorhabditis elegans fat storage
2006 StandoutNobel
Recognition of endotoxin by cells leading to transmembrane signaling
1994
Mechanism of leptin removal from the circulation by the kidney
1997
Central nervous system control of food intake
2000 StandoutNature
CD36 is a sensor of diacylglycerides
2005 StandoutNatureNobel
Feeding and body-weight regulation by hypothalamic neuropeptides—mediation of the actions of leptin
1999
Regulation of receptor-mediated endocytosis by phorbol esters
1991
Leptin induces functional activation of cyclooxygenase‐2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT pathways in human endometrial cancer cells
2008
Neuroendocrine Regulation and Actions of Leptin
1999
Determination of the fold of the core protein of hepatitis B virus by electron cryomicroscopy
1997 Nature
Lipopolysaccharide (LPS) recognition in macrophages. Participation of LPS-binding protein and CD14 in LPS-induced adaptation in rabbit peritoneal exudate macrophages.
1993
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
2003 StandoutNatureNobel
Salmonella typhi uses CFTR to enter intestinal epithelial cells
1998 StandoutNatureNobel
Molecular Biology and Function of CD4 and CD8
1989
Cholesterol Depletion Disrupts Caveolae and Insulin Receptor Signaling for Metabolic Control via Insulin Receptor Substrate-1, but Not for Mitogen-activated Protein Kinase Control
2001
Surprising similarities in structure comparison
1996
Crystal structure of an HIV-binding recombinant fragment of human CD4
1990 StandoutNatureNobel
Leptin accelerates the onset of puberty in normal female mice.
1997
Cerebrospinal Fluid Leptin in Anorexia Nervosa: Correlation with Nutritional Status and Potential Role in Resistance to Weight Gain1
1997
Abnormal splicing of the leptin receptor in diabetic mice
1996 StandoutNature
Virus-induced autoantibody response to a transgenic viral antigen
1990 StandoutNatureNobel
Adipogenesis and Obesity: Rounding Out the Big Picture
1996
Subcutaneous Adipose Tissue Releases Interleukin-6, But Not Tumor Necrosis Factor-α,in Vivo1
1997 Standout
The biology of leptin: a review.
1998
Ligand-independent Dimerization of the Extracellular Domain of the Leptin Receptor and Determination of the Stoichiometry of Leptin Binding
1997
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
1998 Nature
The stomach is a source of leptin
1998 Nature
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
1998 StandoutNature
CD14-dependent Internalization and Metabolism of Extracellular Phosphatidylinositol by Monocytes
1999
From Lesions to Leptin
1999
A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells
1994 StandoutScience
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels
1997 Nature
Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs
1990
Leptin and the regulation of body weight in mammals
1998 StandoutNature
Crystal structure of a hepatitis delta virus ribozyme
1998 StandoutNatureNobel
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
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Hypothalamic CART is a new anorectic peptide regulated by leptin
1998 Nature
Unraveling the central nervous system pathways underlying responses to leptin
1998
Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 Å resolution
1992 StandoutNobel
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
1996
Role of leptin in the neuroendocrine response to fasting
1996 StandoutNature
Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance
1996
Leptin stimulates proliferation and TGF-β expression in renal glomerular endothelial cells: Potential role in glomerulosclerosis
1999
Obesity Wars
2004
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Adipose tissue as an endocrine and paracrine organ
1998
Adipose Tissue as an Endocrine Organ
2004 Standout
Leptin Inhibits Bone Formation through a Hypothalamic Relay
2000 Standout
The immunopathogenesis of sepsis
2002 StandoutNature
Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice
1996 Standout
Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
1996
Phenotypes of Mouse diabetes and Rat fatty Due to Mutations in the OB (Leptin) Receptor
1996 Science
Using mouse models to dissect the genetics of obesity
2002
Whole body leptin kinetics and renal metabolism in vivo
1997
Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes
1997
Role of the kidney in human leptin metabolism
1997
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1998 StandoutScienceNobel
Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia
1992 StandoutScienceNobel
Analysis of Processing and Polyadenylation Signals of the Hepatitis B Virus Surface Antigen Gene by Using Simian Virus 40-Hepatitis B Virus Chimeric Plasmids
1983
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
1999 StandoutNobel
Physiological response to long-term peripheral and central leptin infusion in lean and obese mice
1997
Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance
1998
Divergent Signaling Capacities of the Long and Short Isoforms of the Leptin Receptor
1997
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding.
1990
Protein and carbohydrate structural analysis of a recombinant soluble CD4 receptor by mass spectrometry
1989
Localization of Leptin Receptor (Ob-R) Messenger Ribonucleic Acid in the Rodent Hindbrain*
1998
Regulation of C. elegans Life-Span by Insulinlike Signaling in the Nervous System
2000 StandoutScienceNobel
Phosphorylation of tyrosine-416 is not required for the transforming properties and kinase activity of pp60v-src
1983 StandoutNobel
Defective STAT signaling by the leptin receptor in diabetic mice.
1996
Central leptin modulates behavioral and neural responsivity to CCK
1999
Structure, sequence and expression of the hepatitis delta (δ) viral genome
1986 StandoutNatureNobel
Initiation of translation at internal AUG codons in mammalian cells
1984 Nature
Evidence for the biochemical role of an internal sequence in yeast nuclear mRNA introns: Implications for U1 RNA and metazoan mRNA splicing
1983 StandoutNobel
Human CD4+ T-cell response to hepatitis delta virus: identification of multiple epitopes and characterization of T-helper cytokine profiles
1997 StandoutNobel
The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors.
1996
Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene
1986 StandoutNatureNobel
The hepatitis B virus
1985 Nature
False starts in translational control of gene expression
1985 StandoutNatureNobel
Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor
1998
Effects of Leptin on Insulin Sensitivity in Normal Rats*
1997
Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14.
1993
Evidence for Leptin Binding to Proteins in Serum of Rodents and Humans: Modulation With Obesity
1996
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
1996 StandoutScienceNobel
Trans-activation of HLA-DR gene by hepatitis B virus X gene product.
1990
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
Viruses in Human Cancers
1991 StandoutScienceNobel
T- and B-cell recognition of hepatitis B viral antigens
1988
Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin
1997
Analysis of processing and polyadenylation signals of the hepatitis B virus surface antigen gene by using simian virus 40-hepatitis B virus chimeric plasmids.
1983
A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease
2003 StandoutNobel
Leptin Receptor‐ and STAT3‐Immunoreactivities in Hypocretin/Orexin Neurones of the Lateral Hypothalamus1
1999
Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein
1997 StandoutScience
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
Plasmid-directed synthesis of hepatitis B surface antigen in monkey cells.
1983
Role of N-linked glycans in the interaction between the envelope glycoprotein of human immunodeficiency virus and its CD4 cellular receptor. Structural enzymatic analysis.
1989 StandoutNobel
Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes
1997
Resistance to Endotoxin Shock and Reduced Dissemination of Gram-Negative Bacteria in CD14-Deficient Mice
1996
Fine Structure of the Murine Leptin Receptor Gene: Splice Site Suppression Is Required to Form Two Alternatively Spliced Transcripts
1997
Alignment of Conduits for the Nascent Polypeptide Chain in the Ribosome-Sec61 Complex
1997 StandoutScienceNobel
Influences of antigen processing on the expression of the T cell repertoire. Evidence for MHC-specific hindering structures on the products of processing.
1988
Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus
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Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
1986 StandoutNobel
SIMIAN VIRUS 40 AS A EUKARYOTIC CLONING VEHICLE
1981
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Leptin Receptor Immunoreactivity in Chemically Defined Target Neurons of the Hypothalamus
1998
Reconstitution of the subclass-specific expression of CD4 in thymocytes and peripheral T cells of transgenic mice: identification of a human CD4 enhancer.
1993
Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues
1997
Expression and Characterization of a Putative High Affinity Human Soluble Leptin Receptor
1997
LPS-binding proteins and receptors
1998
Expression of Leptin Receptor Isoforms in Rat Brain Microvessels
1998
Characterizaton of Short Isoforms of the Leptin Receptor in Rat Cerebral Microvessels and of Brain Uptake of Leptin in Mouse Models of Obesity
2002
Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation
1997
Leptin actions on food intake and body temperature are mediated by IL-1
1999
Works of A Moriarty being referenced
Identification and expression cloning of a leptin receptor, OB-R
1995 Standout
Tyrosine Phosphorylation of Tub and Its Association with Src Homology 2 Domain-containing Proteins Implicate Tub in Intracellular Signaling by Insulin
1999
Internalization of the human immunodeficiency virus does not require the cytoplasmic domain of CD4
1988 Nature
Relationship between soluble CD14, lipopolysaccharide binding protein, and the alveolar inflammatory response in patients with acute respiratory distress syndrome.
1997
Antibodies against CD14 protect primates from endotoxin-induced shock.
1996
Lipopolysaccharide binding protein enhances the responsiveness of alveolar macrophages to bacterial lipopolysaccharide. Implications for cytokine production in normal and injured lungs.
1992
Requirement for CD8-major histocompatibility complex class I interaction in positive and negative selection of developing T cells.
1992
Hepatitis delta antigen: antigenic structure and humoral immune response
1990
Immune response to hepatitis B virus core antigen (HBcAg): localization of T cell recognition sites within HBcAg/HBeAg.
1987
A single 10-residue pre-S(1) peptide can prime T cell help for antibody production to multiple epitopes within the pre-S(1), pre-S(2), and S regions of HBsAg.
1987
Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14.
1993
Analysis of lipopolysaccharide binding by CD14.
1993
Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin.
1993
Production of infectious hepatitis delta virus in vitro and neutralization with antibodies directed against hepatitis B virus pre-S antigens
1992
Targeted Deletion of the tub Mouse Obesity Gene Reveals that tubby Is a Loss-of-Function Mutation
2000
Expression of the hepatitis B virus surface antigen gene in cell culture by using a simian virus 40 vector
1981
Antibodies to Peptides Detect New Hepatitis B Antigen: Serological Correlation with Hepatocellular Carcinoma
1985 Science
The position of heterologous epitopes inserted in hepatitis B virus core particles determines their immunogenicity
1992