Citation Impact
Citing Papers
De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination
2003 StandoutNobel
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
High burden and pervasive positive selection of somatic mutations in normal human skin
2015 StandoutScience
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
2009 StandoutNobel
Cutting Edge: Hypermutation in Ig V Genes from Mice Deficient in the MLH1 Mismatch Repair Protein
1999
Saccharomyces cerevisiae MutLα Is a Mismatch Repair Endonuclease
2007 StandoutNobel
Defects of the Mismatch Repair Gene MSH2 Are Implicated in the Development of Murine and Human Lymphoblastic Lymphomas and Are Associated With the Aberrant Expression of Rhombotin-2 (Lmo-2) and Tal-1 (SCL)
1997
Mechanisms in Eukaryotic Mismatch Repair
2006 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Base-excision repair of oxidative DNA damage
2007 StandoutNature
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6
2006
Microsatellite Instability in Colorectal Cancer
2010 Standout
Two levels of protection for the B cell genome during somatic hypermutation
2008 Nature
MutS homologs in mammalian cells
1997
Genetic instabilities in human cancers
1998 StandoutNature
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
Stem cells find their niche
2001 StandoutNature
Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage. Version 4
2000
Impact of genetic engineering on the understanding of spermatogenesis
2001
Mismatch Repair Deficiency Interferes with the Accumulation of Mutations in Chronically Stimulated B Cells and Not with the Hypermutation Process
1998
Human Exonuclease I Is Required for 5′ and 3′ Mismatch Repair
2002 StandoutNobel
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
DNA mismatch repair proteins promote apoptosis and suppress tumorigenesis in response to UVB irradiation: an in vivo study
2004
Mouse models for colorectal cancer
1999
Mutations Predisposing to Hereditary Nonpolyposis Colorectal Cancer
1997
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1999 StandoutNatureNobel
Genetic instability in colorectal cancers
1997 StandoutNature
Female embryonic lethality in mice nullizygous for both Msh2 and p53
1997
MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability
2000
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Mismatch repair and immunoglobulin gene hypermutation: did we learn something?
1999
Isolation of MutSβ from Human Cells and Comparison of the Mismatch Repair Specificities of MutSβ and MutSα
1998 StandoutNobel
Clonal evolution in cancer
2012 StandoutNature
Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA
2003
Identification and Survival of Carriers of Mutations in DNA Mismatch-Repair Genes in Colon Cancer
2006
DNA mismatch repair and cancer
2001
Meiotic Pachytene Arrest in MLH1-Deficient Mice
1996
Mutation in the Mismatch Repair Gene Msh6 Causes Cancer Susceptibility
1997
Mechanisms and functions of DNA mismatch repair
2007
DNA mismatch repair: Molecular mechanism, cancer, and ageing
2008
Mammalian DNA mismatch repair protects cells from UVB-induced DNA damage by facilitating apoptosis and p53 activation
2003
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over
1996
Human Chromosomal Translocations at CpG Sites and a Theoretical Basis for Their Lineage and Stage Specificity
2008
Negative regulation of activation-induced cytidine deaminase in B cells
2006 StandoutNobel
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
1999 StandoutNobel
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Mammalian DNA Mismatch Repair
1999
APC mutations in colorectal tumors with mismatch repair deficiency.
1996
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
Reduced Isotype Switching in Splenic B Cells from Mice Deficient in Mismatch Repair Enzymes
1999
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice
2007 StandoutNobel
Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells.
1997
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Tissues of MSH2-deficient mice demonstrate hypermutability on exposure to a DNA methylating agent
1998
Quality Control by DNA Repair
1999 StandoutScienceNobel
Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation
2011 StandoutNobel
The role of mismatch repair in DNA damage-induced apoptosis.
1999
Deficiencies in Mouse Myh and Ogg1 Result in Tumor Predisposition and G to T Mutations in Codon 12 of the K-Ras Oncogene in Lung Tumors
2004 StandoutNobel
Human MutSα Specifically Binds to DNA Containing Aminofluorene and Acetylaminofluorene Adducts
1996
Different mutator phenotypes in Mlh1 - versus Pms2 -deficient mice
1999
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice
2000
Deletion of an Amino-Terminal Sequence Stabilizes β-Catenin In Vivo and Promotes Hyperphosphorylation of the Adenomatous Polyposis Coli Tumor Suppressor Protein
1996
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
2009 StandoutNobel
Roles of mutation and recombination in the evolution of protein thermodynamics
2002 StandoutNobel
Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice.
1999
Rates of Spontaneous Mutation
1998
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
2009 StandoutNobel
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC −/− Colon Carcinoma
1997 StandoutScience
Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshifts
2000
Mismatch repair in Xenopus egg extracts: DNA strand breaks act as signals rather than excision points.
1996
Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1, N 6 -ethenoadenine and hypoxanthine but not of 3, N 4 -ethenocytosine or 8-oxoguanine
1997
The Mutation Rate and Cancer
1998
Repopulating defect of mismatch repair–deficient hematopoietic stem cells
2003
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Constitutive Expression of AID Leads to Tumorigenesis
2003 StandoutNobel
Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC
1997 StandoutScience
APC binds to the novel protein EB1.
1995
Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation
2011 StandoutNobel
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Human DNA Repair Genes
2001 StandoutScienceNobel
Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin
2003
Variable deletion and duplication at recombination junction ends: Implication for staggered double-strand cleavage in class-switch recombination
2001 StandoutNobel
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
APC mutation and the crypt cycle in murine and human intestine.
1997
Hypermutation in Ig V genes from mice deficient in the MLH1 mismatch repair protein.
1999
Increased Hypermutation at G and C Nucleotides in Immunoglobulin Variable Genes from Mice Deficient in the MSH2 Mismatch Repair Protein
1998
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1
2004 StandoutNobel
Transcription-Coupled Repair Deficiency and Mutations in Human Mismatch Repair Genes
1996 Science
Apoptosis and APC in colorectal tumorigenesis.
1996
Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice
2002 StandoutNobel
Mismatch Repair Proteins MSH2, MLH1, and EXO1 Are Important for Class-Switch Recombination Events Occurring in B Cells That Lack Nonhomologous End Joining
2011
RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells
2003 StandoutNobel
MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis.
1996
Works of A. Mitri being referenced
Mismatch Repair Gene Defects Contribute to the Genetic Basis of Double Primary Cancers of the Colorectum and Endometrium
1999
MSH2 deficient mice are viable and susceptible to lymphoid tumours
1995
Somatic APC and K-ras codon 12 mutations in aberrant crypt foci from human colons.
1994