Standout Papers
Citation Impact
Citing Papers
Global Transposon Mutagenesis and Essential Gene Analysis of Helicobacter pylori
2004
Molecular Analysis of Commensal Host-Microbial Relationships in the Intestine
2001 StandoutScience
SHP-2 Tyrosine Phosphatase as an Intracellular Target of Helicobacter pylori CagA Protein
2002 Science
Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strains
1997
Heterogeneity in the Helicobacter pylori vacA and cagA genes: association with gastroduodenal disease in South Africa?
1999
Profile of Helicobacter pylori cytotoxin derived from two areas of Japan with different prevalence of atrophic gastritis.
1996
Major virulence factors, VacA and CagA, are commonly positive in Helicobacter pylori isolates in Japan
1998
In Vivo Regulation of the IκB Homologue cactus during the Immune Response of Drosophila
1998 StandoutNobel
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
Malignant Helicobacter pylori-Associated Diseases: Gastric Cancer and MALT Lymphoma
2019
Corrected Identity of Isolates of Helicobacter Pylori Reference Strain NCTC11637
1997
Resistance to fever induction and impaired acute-phase response in interleukin-1β-deficient mice
1995
Identification of nonessential Helicobacter pylori genes using random mutagenesis and loop amplification
2001
Variability of gene order in different Helicobacter pylori strains contributes to genome diversity
1996
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
1990 StandoutNature
NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
2011 Standout
Lack of gastritis and of an adaptive immune response in interferon regulatory factor-1-deficient mice infected withHelicobacter pylori
2001
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
1993 Standout
A novel family of phospholipase D homologues that includes phospholipid synthases and putative endonucleases: Identification of duplicated repeats and potential active site residues
1996
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Genetic organization and heterogeneity of the iceA locus of Helicobacter pylori
2000
Emergence of recombinant strains ofHelicobacter pyloriduring human infection
1999
Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin.
1998
Studies on the contribution of c-fos/AP-1 to arthritic joint destruction.
1997
Quasispecies Development ofHelicobacter pyloriObserved in Paired Isolates Obtained Years Apart from the Same Host
2000
Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant
1998
Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori
1998
Systemic sclerosis
2017 Standout
Presence of the cagA Gene in the Majority of Helicobacter pylori Strains Is Independent of Whether the Individual Has Duodenal Ulcer or Asymptomatic Gastritis
1996
The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults
1996 StandoutNobel
Genetic organization of a small cryptic plasmid of Helicobacter pylori
1995
Helicobacter pylori Infection and the Development of Gastric Cancer
2001 Standout
Analysis of the type IV secretion system-dependent cell motility of Helicobacter pylori-infected epithelial cells
2004
Mosaicism in Vacuolating Cytotoxin Alleles of Helicobacter pylori
1995
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
The Interrelationship between Cytotoxin-Associated Gene A, Vacuolating Cytotoxin, and Helicobacter pylori-Related Diseases
1996
Reduced colonization of gastric mucosa by Helicobacter pylori in mice deficient in interleukin‐101
2001
Oncogenic mechanisms of the Helicobacter pylori CagA protein
2004
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
Density of Helicobacter pylori Infection In Vivo as Assessed by Quantitative Culture and Histology
1996
Genetic analysis of the Helicobacter pylori vacuoiating cytotoxin: structural similarities with the IgA protease type of exported protein
1994
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
2014 Nature
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
1997 StandoutNature
Helicobacter pylori Infection and Gastric Lymphoma
1994 Standout
Genetic and functional characterization of the alpAB gene locus essential for the adhesion of Helicobacter pylori to human gastric tissue
1999
The primary transcriptome of the major human pathogen Helicobacter pylori
2010 StandoutNature
Analyses of the cag pathogenicity island of Helicobacter pylori
1998
c‐Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs
2002
Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor
1992 StandoutNature
Expression of mRNA for Interferon-Gamma, Interleukin-10, and Interleukin-12 (p40) in Normal Gastric Mucosa and in Mucosa Infected withHelicobacter pylori
1997
Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori
2004
Helicobacter pylori CagA Containing ITAM‐Like Sequences Localized to Lipid Rafts Negatively Regulates VacA‐Induced Signaling In Vivo
2003
A revised annotation and comparative analysis of Helicobacter pylori genomes
2003
Gut flora in health and disease
2003 Standout
The vacuolating cytotoxin of Helicobacter pylori
1996
Gastric cancer
2020 Standout
Helicobacter pyloriInfection
2002 Standout
Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death
1995 Standout
Prospects for the Development of a Vaccine Against Helicobacter pylori
1996
Attenuation of Helicobacter pylori CagA·SHP-2 Signaling by Interaction between CagA and C-terminal Src Kinase
2003
Ordered cosmid library and high‐resolution physical—genetic map of Helicobacter pylori strain NCTC11638
1994
Recombination and clonal groupings within Helicobacter pylori from different geographical regions
1999
Functional analysis of iceA1, a CATG-recognizing restriction endonuclease gene in Helicobacter pylori
2002
Environmental risk factors of systemic sclerosis
2015
Analysis of iceA1 transcription in Helicobacter pylori
2000
Association between TNF- promoter polymorphism and Helicobacter pylori cagA subtype infection
2001
Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori
1993 Standout
The TNF and TNF Receptor Superfamilies
2001 Standout
Association of Helicobacter pylori genotype with gastroesophageal reflux disease and other upper gastrointestinal diseases
2000
Src Is the Kinase of the Helicobacter pylori CagA Protein in Vitro and in Vivo
2002
Acute-Phase Proteins and Other Systemic Responses to Inflammation
1999 Standout
The response of cells from low-grade B-cell gastric lymphomas of mucosa-associated lymphoid tissue to Helicobacter pylori
1993
Duodenal Helicobacter pylori infection differs in cagA genotype between asymptomatic subjects and patients with duodenal ulcers
1999
Regulation of transcription in Helicobacter pylori: simple systems or complex circuits?
2001
Correlation between Variation of the 3′ Region of thecagAGene inHelicobacter pyloriand Disease Outcome in Japan
2002
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
1993 Standout
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Helicobacter pylori and gastrointestinal tract adenocarcinomas
2002
The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation
2003
Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme
1992 Standout
Vacuolating Toxin Production in Clinical Isolates of Helicobacter pylori with Different vacA Genotypes
1998
Modeling Development and Disease with Organoids
2016 Standout
cPLA2 is phosphorylated and activated by MAP kinase
1993 Standout
The Functional Status of the Helicobacter pylori sabB Adhesin Gene as a Putative Marker for Disease Outcome
2004
Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype.
1995
Yersinia pestis , the cause of plague, is a recently emerged clone of Yersinia pseudotuberculosis
1999 Standout
The crystal structure of urease from Klebsiella aerogenes
1995 StandoutScience
Interleukin 1 induces expression of the human immunodeficiency virus alone and in synergy with interleukin 6 in chronically infected U1 cells: inhibition of inductive effects by the interleukin 1 receptor antagonist.
1994
Translocation of Helicobacter pylori CagA into Gastric Epithelial Cells by Type IV Secretion
2000 StandoutScience
Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection
1997
Virulence Factors of Helicobacter pylori Responsible for Gastric Diseases in Mongolian Gerbil
2000
Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro
1995
Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease.
1994
Tyrosine phosphorylation of theHelicobacter pyloriCagA antigen aftercag-driven host cell translocation
2000
Key importance of the Helicobacter pylori adherence factor blood group antigen binding adhesin during chronic gastric inflammation.
2001
Infection withHelicobacter pyloriExpressing thecagAGene Is Not Associated with an Increased Risk of Developing Peptic Ulcer Diseases in Korean Patients
1998
Production of Mice Deficient in Genes for Interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 Receptor Antagonist Shows that IL-1β Is Crucial in Turpentine-induced Fever Development and Glucocorticoid Secretion
1998
Serologic detection of infection with cagA+ Helicobacter pylori strains
1995
A Conventional Beagle Dog Model for Acute and Chronic Infection withHelicobacter pylori
1999
Gastric Ulcer, Atrophic Gastritis, and Intestinal Metaplasia Caused byHelicobacter pyloriInfection in Mongolian Gerbils
1998
Adaptive mutation and cocolonization during Helicobacter pylori infection of gnotobiotic piglets
1995
A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-kappa B.
1993
cag , a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors
1996 Standout
High Pathogenic Potential of Low-Affinity Autoantibodies in Experimental Autoimmune Hemolytic Anemia
1999 StandoutNobel
Mutation of the cytotoxin-associated cagA gene does not affect the vacuolating cytotoxin activity of Helicobacter pylori
1994
Helicobacter pylori - a conundrum of genetic diversity
1998
Occurrence of gastric ulcers in gnotobiotic piglets colonized by Helicobacter pylori
1995
Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila toll protein are essential for IL-1R signal transduction.
1992
Polymorphisms of Helicobacter pylori HP0638 Reflect Geographic Origin and Correlate with cagA Status
2002
Host Cell Responses to Genotypically SimilarHelicobacter pyloriIsolates from United States and Japan
2002
Proteins Encoded by thecagPathogenicity Island ofHelicobacter pyloriAre Required for NF-κB Activation
1998
Motility of Helicobacter pylori Is Coordinately Regulated by the Transcriptional Activator FlgR, an NtrC Homolog
1999
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
1993 Standout
Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin
1995
Pathogenesis ofHelicobacter pyloriInfection
2006 Standout
Detection ofHelicobacter species in the liver of patients with and without primary liver carcinoma
2000
Vacuolating Cytotoxin of Helicobacter pylori Plays a Role during Colonization in a Mouse Model of Infection
2001
Evaluation of the Association of NineHelicobacter pyloriVirulence Factors with Strains Involved in Low-Grade Gastric Mucosa-Associated Lymphoid Tissue Lymphoma
2004
Characterization of the spontaneous autoimmune (anti-erythrocyte) response in NZB mice using a pathogenic monoclonal autoantibody and its anti-idiotype.
1989
Detection of Helicobacter species in the liver of patients with and without primary liver carcinoma.
2000
Surface localization of Helicobacter pylori urease and a heat shock protein homolog requires bacterial autolysis
1996
Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila.
1995 StandoutNobel
Expanding Allelic Diversity of Helicobacter pylori vacA
1998
CagA/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cell lines.
1994
Development of a Mouse Model of Helicobacter pylori Infection that Mimics Human Disease
1995 Science
A family of human receptors structurally related to Drosophila Toll
1998 Standout
Identification and characterization of an operon of Helicobacter pylori that is involved in motility and stress adaptation
1997
Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach.
1995 Standout
Creating and Maintaining the Gastrointestinal Ecosystem: What We Know and Need To Know from Gnotobiology
1998
Helicobacter pylori Adhesin Binding Fucosylated Histo-Blood Group Antigens Revealed by Retagging
1998 StandoutScience
Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone.
1996
Structural organization of the genes for murine and human leukemia inhibitory factor. Evolutionary conservation of coding and non-coding regions.
1990
Helicobacter pylori-Induced Mucosal Inflammation Is Th1 Mediated and Exacerbated in IL-4, But Not IFN-γ, Gene-Deficient Mice
2000
Helicobacter pylori Virulence and Genetic Geography
1999 StandoutScience
Metabolism and Genetics of Helicobacter pylori : the Genome Era
1999
Expression of membrane interleukin 1 by fibroblasts transfected with murine pro-interleukin 1 alpha cDNA.
1988
cagA -Positive Helicobacter pylori Populations in China and The Netherlands Are Distinct
1998
Helicobacter pylori Caga Protein Can Be Tyrosine Phosphorylated in Gastric Epithelial Cells
2000
HIV replication in CD4+T cells of HIV-infected individuals is regulated by a balance between the viral suppressive effects of endogenous β-chemokines and the viral inductive effects of other endogenous cytokines
1996 StandoutNobel
Vacuolating Toxin Gene Polymorphism amongHelicobacter pyloriClinical Isolates and Its Association with m1, m2, or ChimericvacAMiddle Types
1998
GENETIC ANALYSIS OF HOST RESISTANCE: Toll-Like Receptor Signaling and Immunity at Large
2006 StandoutNobel
Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease
1995
TheHelicobacter pyloriplasticity region locusjhp0947âjhp0949is associated with duodenal ulcer disease and interleukin-12 production in monocyte cells
2004
Experimental Infection of Mongolian Gerbils with Wild-Type and Mutant Helicobacter pylori Strains
1998
Interleukin-1 represents a new modality for the activation of extracellular signal-regulated kinases/microtubule-associated protein-2 kinases.
1991
pH-Regulated Gene Expression of the Gastric PathogenHelicobacter pylori
2003
Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites
2002
The New Path to Preventing Ulcers
1995 Science
Analysis and typing of the vacA gene from cagA-positive strains of Helicobacter pylori isolated in Japan
1997
Structure of cag pathogenicity island in Japanese Helicobacter pyloriisolates
1999
Spiral Bacteria in the Human Stomach: The Gastric Helicobacters
1995
Interleukin-1 and interleukin-1 antagonism
1991 Standout
Induction of host signal transduction pathways by Helicobacter pylori
1997
Metabolism of ubiquitinated histones.
1981 StandoutNobel
Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains.
1994
The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity
1998
Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori.
1995
Distinct Variants of Helicobacter pylori cagA Are Associated with vacA Subtypes
1999
SMART, a simple modular architecture research tool: Identification of signaling domains
1998 Standout
Chemical Glycoproteomics
2016 StandoutNobel
Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin
1999
Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis
1998 StandoutScience
Iron acquisition and virulence in Helicobacter pylori: a major role for FeoB, a high‐affinity ferrous iron transporter
2000
Works of A. Massone being referenced
Simple Immunization Protocol for High Frequency Production of Soluble Antigen-Specific Hybridomas
1983
The Hsp60 protein of Helicobacter pylori: structure and immune response in patients with gastroduodenal diseases
1993
p21ras contributes to HIV‐1 activation in T‐cells
1992
Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer.
1993 Standout
The murine interleukin 1β gene: structure and evolution
1986
Mapping of biologically relevant sites on human IL-1 beta using monoclonal antibodies.
1988
A role for protein kinase C activity in interleukin-1 (IL-1) induction of IL-2 gene expression but not in IL-1 signal transduction.
1990