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Citing Papers
Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage Non–Small-Cell Lung Cancer
2008 Standout
Cell culture models for oxidative stress: superoxide and hydrogen peroxide versus normobaric hyperoxia
1992
Anin vitrostudy of bare and poly(ethylene glycol)-co-fumarate-coated superparamagnetic iron oxide nanoparticles: a new toxicity identification procedure
2009
5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers
2004
Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression
2003
In vitro uptake of polystyrene microspheres: effect of particle size, cell line and cell density
2001
DNA methylation patterns and epigenetic memory
2002 Standout
Nucleotide signalling during inflammation
2014 StandoutNature
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
The dual role of thymidine phosphorylase in cancer development and chemotherapy
2009
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
Genetic toxicology of oxygen
1989
Denufosol: A review of studies with inhaled P2Y2 agonists that led to Phase 3
2008
Oligodendroglioma: An Appraisal of Recent Data Pertaining to Diagnosis and Treatment
1999
Metabolism and action of amino acid analog anti-cancer agents
1990
Cancer metastasis: tumor cell and host organ properties important in metastasis to specific secondary sites
1988
An Expanded Set of Amino Acid Analogs for the Ribosomal Translation of Unnatural Peptides
2007 StandoutNobel
Otto Warburg's contributions to current concepts of cancer metabolism
2011 Standout
Cytotoxic chemotherapy induces cell differentiation in small-cell lung carcinoma.
1991
Phyto-oestrogens and Western Diseases
1997 Standout
Chemotherapy for anaplastic oligodendroglioma. National Cancer Institute of Canada Clinical Trials Group.
1994
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited
2003 Standout
Polyphenols: food sources and bioavailability
2004 Standout
Malignant Gliomas in Adults
2008 Standout
Gene Silencing in Cancer in Association with Promoter Hypermethylation
2003 Standout
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
2003 Standout
DNA Methylation Inhibitors in the Treatment of Leukemias, Myelodysplastic Syndromes and Hemoglobinopathies: Clinical Results and Possible Mechanisms of Action
2000
Resveratrol Inhibits Cyclooxygenase-2 Transcription and Activity in Phorbol Ester-treated Human Mammary Epithelial Cells
1998 Standout
A new approach for the in vitro identification of the cytotoxicity of superparamagnetic iron oxide nanoparticles
2009
Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults
1993
Relation of cellular drug resistance to long-term clinical outcome in childhood acute lymphoblastic leukaemia
1991
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Cell, tissue and organ culture as in vitro models to study the biology of squamous cell carcinomas of the head and neck
1996
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Primary brain tumours in adults
2012 Standout
Hormonal Regulation of Chick Kidney Inhibitor of Adenosine 3',5'-Monophosphate-Dependent Protein Kinase*
1989
Sequence-dependent growth inhibition and DNA damage formation by the irinotecan–5-fluorouracil combination in human colon carcinoma cell lines
1999
5-Fluorouracil: mechanisms of action and clinical strategies
2003 Standout
DNA damage by oxygen‐derived species Its mechanism and measurement in mammalian systems
1991
Computational design of orthogonal nucleoside kinases
2010 StandoutNobel
Clinical Pharmacology of 5-Fluorouracil
1989 Standout
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
2002
The fundamental role of epigenetic events in cancer
2002 Standout
Mammalian deoxyribonucleoside kinases
1995
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Brain Tumors
2001 Standout
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
2007 Standout
Oxidative damage and mitochondrial decay in aging.
1994 Standout
Testing an “In-Out” Targeting Procedure for Making Subtle Genomic Modifications in Mouse Embryonic Stem Cells
1991 StandoutNobel
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Glutamine and glucose metabolism during thymocyte proliferation. Pathways of glutamine and glutamate metabolism
1985
Human Bone Marrow Mesenchymal Stem Cell Behaviors on PCL/Gelatin Nanofibrous Scaffolds Modified with A Collagen IV-Derived RGD-Containing Peptide.
1979
5-Fluorouracil Incorporated into DNA Is Excised by the Smug1 DNA Glycosylase to Reduce Drug Cytotoxicity
2007 StandoutNobel
Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat.
1991
Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2′-deoxycytidine (decitabine) treatment
2002
The Efficacy of Azidothymidine (AZT) in the Treatment of Patients with AIDS and AIDS-Related Complex
1987 Standout
FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
2011 Standout
Production of the effector molecule thymidine by human lung alveolar macrophages
1984
Association of thrombospondin-1 with osteogenic differentiation of retinal pericytes in vitro
1996
Oxidative Nucleobase Modifications Leading to Strand Scission
1998 Standout
The effect of particle design on cellular internalization pathways
2008 Standout
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Prednisolone Resistance in Childhood Acute Lymphoblastic Leukemia: Vitro-Vivo Correlations and Cross-Resistance to Other Drugs
1998
Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells.
1991 StandoutNobel
Expression of the MAGE-1 tumor antigen is up-regulated by the demethylating agent 5-aza-2'-deoxycytidine.
1994
Inhibition of inosinate dehydrogenase by metabolites of 2-β-D-ribofuranosylthiazole-4-car☐amide
1982
Sensitivity to L-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+ pediatric ALL
2002
The HPRT locus
1979
Transbilayer movement of fluorescent analogs of phosphatidylserine and phosphatidylethanolamine at the plasma membrane of cultured cells. Evidence for a protein-mediated and ATP-dependent process(es).
1987
Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation.
1994
Chemistry of Biologically Important Synthetic Organoselenium Compounds
2001 Standout
Mammalian red cell membrane Rh polypeptides are selectively palmitoylated subunits of a macromolecular complex.
1992 StandoutNobel
Core/Shell Nanoparticles: Classes, Properties, Synthesis Mechanisms, Characterization, and Applications
2011 Standout
Thermostable inhibitor of cAMP-dependent protein kinase enhances the rate of export of the kinase catalytic subunit from the nucleus.
1994 StandoutNobel
Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility, Pharmaceutical and Biomedical Applications
2012 Standout
Enzymatic aminoacylation of tRNA with unnatural amino acids
2006 StandoutNobel
Enhancement of glomerular mesangial cell neutral proteinase secretion by macrophages: role of interleukin 1.
1986
Secretory products of macrophages.
1987 Standout
Gold-Catalyzed Carbon−Heteroatom Bond-Forming Reactions
2011 Standout
Phosphate uptake by kidney epithelial (LLC-PK1) cells
1984
Isolation of Chinese hamster cell mutants defective in the receptor-mediated endocytosis of low density lipoprotein
1981 StandoutNobel
In Vitro Cellular Drug Resistance and Prognosis in Newly Diagnosed Childhood Acute Lymphoblastic Leukemia
1997
5-HT1A and histamine H1 receptors in HeLa cells stimulate phosphoinositide hydrolysis and phosphate uptake via distinct G protein pools.
1991 StandoutNobel
Metabolic Alterations Associated with Proliferation of Mitogen-Activated Lymphocytes and of Lymphoblastoid Cell Lines: Evaluation of Glucose and Glutamine Metabolism
1986
Lung Perfusion Imaging with Monosized Biodegradable Microspheres
2010
Microwave-assisted gold(I) catalyzed pyran ring opening in brevifloralactone: synthesis of the hawtriwaic acid core
2008
Emerging Droplet Microfluidics
2017 Standout
Vascular Calcification
2008 Standout
The Human 5-HT1A Receptor Expressed in HeLa Cells Stimulates Sodium-dependent Phosphate Uptake via Protein Kinase C
1989 StandoutNobel
Effect of human renal and hepatic disease on the pharmacokinetics of anticancer drugs
1982
Uridine phosphorylase (-/-) murine embryonic stem cells clarify the key role of this enzyme in the regulation of the pyrimidine salvage pathway and in the activation of fluoropyrimidines.
2002
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line
1992 StandoutScience
Works of A. Leyva being referenced
Antiproliferative effects of compounds derived from plants of Northeast Brazil
2000
Adaptation of the rapid automated tetrazolium dye based (MTT) assay for chemosensitivity testing in childhood leukemia
1988
Deoxycytidine kinase and deoxycytidine deaminase activities in human tumour xenografts
1993
In vitro biochemical and in vivo biological studies of the uridine 'rescue' of 5-fluorouracil
1988
Chromosomal instability in an oxygen-tolerant variant of Chinese hamster ovary cells
1989
Anti‐tumor and differentiation‐inducing activity of n,n‐dimethylformamide (dmf) in head‐and‐neck cancer xenografts
1989
Comparison of the rapid automated MTT-assay with a dye exclusion assay for chemosensitivity testing in childhood leukaemia
1989
Influence of portein tyrosine phosphorylation on the experssion of the c‐myc oncogene in cancer of the large bowel
1995
Purine nucleosides as cell-specific modulators of 5-fluorouracil metabolism and cytotoxicity
1987
Phase I and pharmacokinetic study of 5-aza-2'-deoxycytidine (NSC 127716) in cancer patients.
1986
Clinical and pharmacokinetic studies of prolonged administration of high-dose uridine intended for rescue from 5-FU toxicity.
1986
Sensitivity of human, murine, and rat cells to 5-fluorouracil and 5'-deoxy-5-fluorouridine in relation to drug-metabolizing enzymes.
1986
Measurement of DNA in cultured human cells
1974
Determination of N-(Phosphonacetyl)-l-Aspartic acid (PALA) in plasma and urine by high pressure liquid chromatography
1980
Purine modulation of thymidine activity in L1210 leukemia cells in vitro
1982
Effect of 6-mercaptopurine on inosinic acid dehydrogenase in cultured human fibroblasts
1976
Analysis of Human Ascites Effect on Clonogenic Growth of Human Tumor Cell Lines and NRK‐49F Cells in Soft Agar
1987
Is there a role for thymidine in cancer chemotherapy?
1982
Inhibition of cell growth by N-(phosphonacetyl)-L-aspartate in human and murine cells in vitro☆
1981
Concentrations of N-(Phosphonacetyl)-l-aspartate (PALA) in plasma and tears in man
1981
Methotrexate cytotoxicity: studies on its reversal by folates and nucleosides.
1981
Mutagen-induced diploid human lymphoblast variants containing altered hypoxanthine guanine phosphoribosyl transferase
1977