Citation Impact
Citing Papers
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
2003
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation
2007
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch
2004 StandoutScienceNobel
Hepatitis C Virus E2-CD81 Interaction Induces Hypermutation of the Immunoglobulin Gene in B Cells
2005
Discovery of Activation‐Induced Cytidine Deaminase, the Engraver of Antibody Memory
2007 StandoutNobel
T Cell-Independent Somatic Hypermutation in Murine B Cells with an Immature Phenotype
2004
Mutations occur in the Ig S region but rarely in S regions prior to class switch recombination
2003
Clinical-grade manufacturing of autologous mature mRNA-electroporated dendritic cells and safety testing in acute myeloid leukemia patients in a phase I dose-escalation clinical trial
2009
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Immunoglobulin gene conversion: Insights from bursal B cells and the DT40 cell line
2004
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
The role of the non‐homologous end‐joining pathway in lymphocyte development
2004
AID-Dependent Generation of Resected Double-Strand DNA Breaks and Recruitment of Rad52/Rad51 in Somatic Hypermutation
2003
Class-switch recombination: interplay of transcription, DNA deamination and DNA repair
2004
Role of AID in Tumorigenesis
2007 StandoutNobel
Down-regulation of DNA polymerase β accompanies somatic hypermutation in human BL2 cell lines
2006
Histone Modifications Associated with Somatic Hypermutation
2005
Hyper-IgM syndrome type 4 with a B lymphocyte–intrinsic selective deficiency in Ig class-switch recombination
2003
Expression of Activation-Induced Cytidine Deaminase (AID) in Burkitt Lymphoma Cells: Rare AID-Negative Cell Lines with the Unmutated Rearranged VHGene
2003
Systemic lupus erythematosus
2001
AID is required for germinal center–derived lymphomagenesis
2007 StandoutNobel
Transcription-targeted DNA deamination by the AID antibody diversification enzyme
2003 Nature
Development of Autoantibodies before the Clinical Onset of Systemic Lupus Erythematosus
2003 Standout
The generation of antibody diversity through somatic hypermutation and class switch recombination
2004
The Histone Chaperone Spt6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H3K4me3 Regulation
2012 StandoutNobel
The regulation of somatic hypermutation
2004
The mechanisms of immune diversification and their disorders
2003
What role for AID: mutator, or assembler of the immunoglobulin mutasome?
2003
A coming-of-age story: activation-induced cytidine deaminase turns 10
2009
Immunity, Inflammation, and Cancer
2010 Standout
Requirement of Non-canonical Activity of Uracil DNA Glycosylase for Class Switch Recombination
2006 StandoutNobel
Somatic hypermutation at A·T pairs: polymerase error versus dUTP incorporation
2005
Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota
2002 Nature
Aid
2004 StandoutNobel
AID mutant analyses indicate requirement for class-switch-specific cofactors
2003 StandoutNobel
Activation-induced cytidine deaminase expression in follicular lymphoma: association between AID expression and ongoing mutation in FL
2004
Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability
2016 StandoutNobel
The AID Dilemma
2012 StandoutNobel
DNA-Dependent Protein Kinase Inhibits AID-Induced Antibody Gene Conversion
2007
Presence of somatic hypermutation and activation‐induced cytidine deaminase in acute lymphoblastic leukemia L2 with t(14;18)(q32;q21)
2004
Induction of Somatic Hypermutation Is Associated with Modifications in Immunoglobulin Variable Region Chromatin
2003
Negative regulation of activation-induced cytidine deaminase in B cells
2006 StandoutNobel
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
DNA Polymerase η Is Involved in Hypermutation Occurring during Immunoglobulin Class Switch Recombination
2004
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
A novel human B cell subpopulation representing the initial germinal center population to express AID
2006
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice
2007 StandoutNobel
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Expression of activation-induced cytidine deaminase is confined to B-cell non-Hodgkin's lymphomas of germinal-center phenotype.
2003
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation
2011 StandoutNobel
Normal Somatic Hypermutation of Ig Genes in the Absence of 8-Hydroxyguanine-DNA Glycosylase
2003 StandoutNobel
Expression of the AID protein in normal and neoplastic B cells
2004
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
2016 StandoutScience
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
2009 StandoutNobel
Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination
2009 StandoutNobel
The Block in Immunoglobulin Class Switch Recombination Caused by Activation-Induced Cytidine Deaminase Deficiency Occurs Prior to the Generation of DNA Double Strand Breaks in Switch μ Region
2003
Hairy cell leukemia: at the crossroad of somatic mutation and isotype switch
2004
The Biochemistry of Somatic Hypermutation
2008
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Ongoing In Vivo Immunoglobulin Class Switch DNA Recombination in Chronic Lymphocytic Leukemia B Cells
2002
Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutation
2003
AID Mediates Hypermutation by Deaminating Single Stranded DNA
2003
DNA cleavage in immunoglobulin somatic hypermutation depends onde novoprotein synthesis but not on uracil DNA glycosylase
2005 StandoutNobel
Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders
2005 StandoutNobel
RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase
2013 StandoutNobel
B Lymphocyte Activation by Human Papillomavirus-Like Particles Directly Induces Ig Class Switch Recombination via TLR4-MyD88
2005
Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants
2008 StandoutNobel
Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation
2011 StandoutNobel
Evolutionary Comparison of the Mechanism of DNA Cleavage with Respect to Immune Diversity and Genomic Instability
2012 StandoutNobel
Advantages and Disadvantages of Cytidine Deamination
2004
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
Somatic hypermutation of the B cell receptor genesB29(Igβ, CD79b) andmb1(Igα, CD79a)
2003
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1
2004 StandoutNobel
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1
2004
De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination
2004 StandoutNobel
RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells
2003 StandoutNobel
Human Activation-Induced Cytidine Deaminase Is Induced by IL-4 and Negatively Regulated by CD45: Implication of CD45 as a Janus Kinase Phosphatase in Antibody Diversification
2003
Works of A. Léon being referenced
AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line
2002
A closed and single‐use system for monocyte enrichment: potential for dendritic cell generation for clinical applications
2003
Control of severe systemic lupus erythematosus after high-dose immunusuppressive therapy and transplantation of CD34+ purified autologous stem cells from peripheral blood
1999