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Citing Papers
Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity
2013 StandoutNobel
Escherichia coli Induces DNA Double-Strand Breaks in Eukaryotic Cells
2006 Science
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
2007 Standout
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
2008 Standout
Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota
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Management of Helicobacter pylori infection—the Maastricht IV/ Florence Consensus Report
2012 Standout
Conversion of PtdIns(4,5)P2 into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology
2002
Essential role of Helicobacter pyloriγ‐glutamyltranspeptidase for the colonization of the gastric mucosa of mice
1999
Extended Virulence Genotypes ofEscherichia coliStrains from Patients with Urosepsis in Relation to Phylogeny and Host Compromise
2000 Standout
Characterization of the genes rdxA and frxA involved in metronidazole resistance in Helicobacter pylori
2003
Distinct Mechanism of Helicobacter pylori-mediated NF-κB Activation between Gastric Cancer Cells and Monocytic Cells
2001
Immunization of BALB/c mice with Helicobacter urease B induces a T helper 2 response absent in Helicobacter infection
1998
Identification of nonessential Helicobacter pylori genes using random mutagenesis and loop amplification
2001
Variability of gene order in different Helicobacter pylori strains contributes to genome diversity
1996
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
2011 Standout
Bacterial proteins binding to the mammalian extracellular matrix
1993
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
Lethality and centrality in protein networks
2001 StandoutNature
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Unravelling the pathogenic role of Helicobacter pylori in peptic ulcer: Potential new therapies and vaccines
1994
Which test to use to detect Helicobacter pylori infection in patients with low-grade gastric mucosa-associated lymphoid tissue lymphoma?
2003
Deficiency in OGG1 Protects against Inflammation and Mutagenic Effects Associated with H. pylori Infection in Mouse
2006
Helicobacter pylori flagellins have very low intrinsic activity to stimulate human gastric epithelial cells via TLR5
2003
Emergence of recombinant strains ofHelicobacter pyloriduring human infection
1999
Characterisation of the urease-encoding gene complex of Yersinia enterocolitica
1994
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin.
1998
Reduced activation of inflammatory responses in host cells by mouse-adapted Helicobacter pylori isolates
2002
Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant
1998
Development of vaccinesagainst Helicobacter pylori
2009
IMMUNOLOGY OF HELICOBACTER PYLORI AND PROSPECTS FOR VACCINE
2000
Inflammatory bowel disease: cause and immunobiology
2007 Standout
Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for CagA translocation in host cells and induction of interleukin‐8
2001
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
2004 Standout
Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease
1998
A New Helicobacter pylori Vacuolating Cytotoxin Determinant, the Intermediate Region, Is Associated With Gastric Cancer
2007
Rho GTPases in cell biology
2002 StandoutNature
Vaccination of Gnotobiotic Piglets againstHelicobacter pylori
1998
Oral immunization with urease and Escherichia coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori–infected adults
1999
Increased frequency of intestinal Escherichia coli carrying genes for S fimbriae and haemolysin in IgA-deficient individuals
2002
Molecular mimicry between Helicobacter pylori and the host
1997
Identification of Loci Essential for the Growth ofHelicobacter pyloriunder Acidic Conditions
2000
Is the molecular basis of metronidazole resistance in microaerophilic organisms understood?
2002
Helicobacter pylori: microbiology of a ‘slow’ bacterial infection
1993
Cloning and genetic characterization of a Hellcobacter pylori flagellin gene
1992
Impact of Helicobacter pylori resistance to clarithromycin on the efficacy of the omeprazole–amoxicillin–clarithromycin therapy
2001
Sequence of the Proteus mirabilis urease accessory gene ureG
1993
Host Response and Vaccine Development to Helicobacter pylori Infection
1999
Crohn's disease
2016 Standout
Inflammatory Bowel Disease
2002 Standout
Aflagellated mutants of Helicobacter pylori generated by genetic transformation of naturally competent strains using transposon shuttle mutagenesis
1993
Genetic analysis of the Helicobacter pylori vacuoiating cytotoxin: structural similarities with the IgA protease type of exported protein
1994
The protein–protein interaction map of Helicobacter pylori
2001 Nature
The complex flagella of gastric Helicobacter species
1995
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease
2004 Standout
The primary transcriptome of the major human pathogen Helicobacter pylori
2010 StandoutNature
Analyses of the cag pathogenicity island of Helicobacter pylori
1998
Responsiveness to acidity via metal ion regulators mediates virulence in the gastric pathogen Helicobacter pylori
2004
Functions of Bacterial Flagella
1996
Helicobacter pyloriInfection
2010
H pylori antibiotic resistance: prevalence, importance, and advances in testing
2004 Standout
Complement
2001 Standout
Helicobacter pyloriInfection
2002 Standout
Microbial hydrogenases: Primary structure, classification, signatures and phylogeny
1993
Uncomplicated Urinary Tract Infection
2012 Standout
Rho and Rac Take Center Stage
2004 Standout
Crystal structure of the nickel–iron hydrogenase from Desulfovibrio gigas
1995 StandoutNature
Prospects for the Development of a Vaccine Against Helicobacter pylori
1996
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Ordered cosmid library and high‐resolution physical—genetic map of Helicobacter pylori strain NCTC11638
1994
Recombination and clonal groupings within Helicobacter pylori from different geographical regions
1999
Identification of the urease operon in Helicobacter pylori and its control by mRNA decay in response to pH
2000
Signal transduction and virulence regulation in human and animal pathogens
1993
Bacterial ureases: structure, regulation of expression and role in pathogenesis
1993
Review article: the treatment of refractory Helicobacter pylori infection
2003
Activation of Helicobacter pylori ureA promoter by a hybrid Escherichia coli–H. pylori rpoD gene in E. coli
1999
Site‐directed mutagenesis of Klebsiella aerogenes urease: Identification of histidine residues that appear to function in nickel ligation, substrate binding, and catalysis
1993
Peptic ulcer disease
2009
Molecular testing for antibiotic resistance in Helicobacter pylori
2002
Helicobacter pylori nickel‐transport gene nixA: synthesis of catalytically active urease in Escherichia coli independent of growth conditions
1995
Helicobacter pylori Urease.
1995
A Comprehensive Sequence and Disease Correlation Analyses for the C-Terminal Region of CagA Protein of Helicobacter pylori
2009
Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report
2006 Standout
Update on therapeutic options for Helicobacter pylori-related diseases
2005
Purification and characterization of Klebsiella aerogenes UreE protein: A nickel‐binding protein that functions in urease metallocenter assembly
1993
Rho GTPases as Targets of Bacterial Protein Toxins
2000
Human complement regulators: a major target for pathogenic microorganisms
2000
Guidelines for the Management of Helicobacter pylori Infection in Japan: 2009 Revised Edition
2010
Microbial virulence determinants and the pathogenesis of urinary tract infection
2003
The Helicobacter pylori UreI Protein Is Not Involved in Urease Activity but Is Essential for Bacterial Survival In Vivo
1998
Yersinia pestis , the cause of plague, is a recently emerged clone of Yersinia pseudotuberculosis
1999 Standout
The structure of LepA, the ribosomal back translocase
2008 StandoutNobel
The crystal structure of urease from Klebsiella aerogenes
1995 StandoutScience
Translocation of Helicobacter pylori CagA into Gastric Epithelial Cells by Type IV Secretion
2000 StandoutScience
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
2009 StandoutNobel
Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection
1997
Antisense RNA Modulation of Alkyl Hydroperoxide Reductase Levels in Helicobacter pylori Correlates with Organic Peroxide Toxicity but Not Infectivity
2007
23S rRNA base pair 2057–2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G
2005 StandoutNobel
Cloning, sequencing, and expression of thermophilic Bacillus sp. strain TB-90 urease gene complex in Escherichia coli
1994
Construction of a Helicobacter pylori genome map and demonstration of diversity at the genome level
1992
Rectal and Intranasal Immunizations with Recombinant Urease Induce Distinct Local and Serum Immune Responses in Mice and Protect against Helicobacter pylori Infection
1998
Helicobacter pyloriand Gastric Cancer: Factors That Modulate Disease Risk
2010
Roles of FrxA and RdxA Nitroreductases of Helicobacter pylori in Susceptibility and Resistance to Metronidazole
2001
Identification of the essential cysteine residue in Klebsiella aerogenes urease.
1991
Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments.
1994
Immunization of Mice with Urease Vaccine Affords Protection against Helicobacter pylori Infection in the Absence of Antibodies and Is Mediated by MHC Class II–restricted Responses
1998
Helicobacter pyloriDetection and Antimicrobial Susceptibility Testing
2007
Inorganic polyphosphate is needed for swimming, swarming, and twitching motilities of Pseudomonas aeruginosa
2000 Standout
Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer.
1993 Standout
Structural and Functional Aspects of Metal Sites in Biology
1996 Standout
cag , a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors
1996 Standout
Immunization against NaturalHelicobacter pyloriInfection in Nonhuman Primates
1998
The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response
2000 StandoutNobel
MACROPHAGE RECEPTORS AND IMMUNE RECOGNITION
2005
Immune Responses of Specific-Pathogen-Free Mice to Chronic Helicobacter pylori (Strain SS1) Infection
1998
High Levels of Resistance to Metronidazole and Clarithromycin in Helicobacter pylori Strains in Children
2001
Surface proteins from Helicobacter pylori exhibit chemotactic activity for human leukocytes and are present in gastric mucosa.
1992
Common themes in microbial pathogenicity revisited.
1997
GENETICS OF CAMPYLOBACTER AND HELICOBACTER
1992
Exploitation of Mammalian Host Cell Functions by Bacterial Pathogens
1997 Science
Hydrogenases
2014 Standout
Pathogenicity of Helicobacter pylori: a perspective
1993
Common themes in microbial pathogenicity revisited
1997 Standout
Organization of Ureaplasma urealyticum urease gene cluster and expression in a suppressor strain of Escherichia coli
1996 StandoutNobel
Motility of Helicobacter pylori Is Coordinately Regulated by the Transcriptional Activator FlgR, an NtrC Homolog
1999
Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin
1995
Pathogenesis ofHelicobacter pyloriInfection
2006 Standout
Helicobacter pyloriInfection in Immunized Mice Lacking Major Histocompatibility Complex Class I and Class II Functions
1999
Surface localization of Helicobacter pylori urease and a heat shock protein homolog requires bacterial autolysis
1996
Emergence of DiverseHelicobacterSpecies in the Pathogenesis of Gastric and Enterohepatic Diseases
2001
Gene clusters encoding the cytotoxic necrotizing factor type 1, Prs-fimbriae and α-hemolysin form the pathogenicity island II of the uropathogenicEscherichia colistrain J96
1995
Molecular biology of microbial ureases
1995 Standout
Development of a Mouse Model of Helicobacter pylori Infection that Mimics Human Disease
1995 Science
Diverse and abundant antibiotic resistance genes in Chinese swine farms
2013 Standout
Effect of gastric pH on urease-dependent colonization of gnotobiotic piglets by Helicobacter pylori
1994
Free recombination within Helicobacter pylori
1998
Identification and characterization of an operon of Helicobacter pylori that is involved in motility and stress adaptation
1997
Frontiers, Opportunities, and Challenges in Biochemical and Chemical Catalysis of CO2 Fixation
2013 Standout
Genetic requirements for mycobacterial survival during infection
2003 Standout
Helicobacter pylori Adhesin Binding Fucosylated Histo-Blood Group Antigens Revealed by Retagging
1998 StandoutScience
Acid-Induced Activation of the Urease Promoters Is Mediated Directly by the ArsRS Two-Component System of Helicobacter pylori
2005
Klebsiella aerogenes urease gene cluster: sequence of ureD and demonstration that four accessory genes (ureD, ureE, ureF, and ureG) are involved in nickel metallocenter biosynthesis
1992
Helicobacter pylori Virulence and Genetic Geography
1999 StandoutScience
A H + -Gated Urea Channel: The Link Between Helicobacter pylori Urease and Gastric Colonization
2000 Science
cagA -Positive Helicobacter pylori Populations in China and The Netherlands Are Distinct
1998
Vacuolating Toxin Gene Polymorphism amongHelicobacter pyloriClinical Isolates and Its Association with m1, m2, or ChimericvacAMiddle Types
1998
cagA Status and Eradication Treatment Outcome of Anti- Helicobacter pylori Triple Therapies in Patients with Nonulcer Dyspepsia
2001
Gene Expression Profiling of Helicobacter pylori Reveals a Growth-Phase-Dependent Switch in Virulence Gene Expression
2003
Insertion Sequences
1998
pH-Regulated Gene Expression of the Gastric PathogenHelicobacter pylori
2003
Mutation frequency and biological cost of antibiotic resistance in Helicobacter pylori
2001
Antibody to Langerin/CD207 localizes large numbers of CD8α + dendritic cells to the marginal zone of mouse spleen
2009 StandoutNobel
Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains.
1994
Differentiation of Metronidazole-Sensitive and -Resistant Clinical Isolates of Helicobacter pylori by Immunoblotting with Antisera to the RdxA Protein
2001
Works of A Labigne being referenced
The role of the rdxA gene in the evolution of metronidazole resistance in Helicobacter pylori
1999
Local immunoglobulin G antibodies in the stomach may contribute to immunity against Helicobacter infection in mice
1997
Cloning of Campylobacter jejuni genes required for leucine biosynthesis, and construction of leu-negative mutant of C. jejuni by shuttle transposon mutagenesis
1992
Heat shock proteins of Helicobacter pylori.
1996
Genotyping of Helicobacter pylori isolates by sequencing of PCR products and comparison with the RAPD technique
1996
Second‐line treatment for failure to eradicate Helicobacter pylori: a randomized trial comparing four treatment strategies
2003
Production of the RdxA protein in metronidazole-susceptible and -resistant isolates of Helicobacter pylori cultured from treated mice
2002
Clinical outcome after infection with Helicobacter pylori does not appear to be reliably predicted by the presence of any of the genes of the cag pathogenicity island
1998
The GroES homolog of Helicobacter pylori confers protective immunity against mucosal infection in mice.
1995
[Development of genetic and molecular approaches for the diagnosis and study of the pathogenicity of Helicobacter pylori, agent of gastric inflammatory diseases].
1992
Adhesion to and invasion of HeLa cells by pathogenic Escherichia coli carrying the afa-3 gene cluster are mediated by the AfaE and AfaD proteins, respectively
1997
Rapid and specific detection of the pap, afa, and sfa adhesin-encoding operons in uropathogenic Escherichia coli strains by polymerase chain reaction
1992
The Dr hemagglutinin, afimbrial adhesins AFA-I and AFA-III, and F1845 fimbriae of uropathogenic and diarrhea-associated Escherichia coli belong to a family of hemagglutinins with Dr receptor recognition
1990
Determinants of Helicobacter pylori pathogenicity.
1996
Nucleotide sequence of the afimbrial-adhesin-encoding afa-3 gene cluster and its translocation via flanking IS1 insertion sequences
1994
Comparative ultrastructural and functional studies of Helicobacter pylori and Helicobacter mustelae flagellin mutants: both flagellin subunits, FlaA and FlaB, are necessary for full motility in Helicobacter species
1995
The Helicobacter pylori ureC gene codes for a phosphoglucosamine mutase
1997
Characterization of plasmid-borne afa-3 gene clusters encoding afimbrial adhesins expressed by Escherichia coli strains associated with intestinal or urinary tract infections
1993
Shuttle cloning and nucleotide sequences of Helicobacter pylori genes responsible for urease activity
1991
Helicobacter pylori requires an acidic environment to survive in the presence of urea
1995
Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers.
1994
Expression of Helicobacter pylori urease genes in Escherichia coli grown under nitrogen-limiting conditions
1992
Cloning and genetic characterization of the Helicobacter pylori and Helicobacter mustelae flaB flagellin genes and construction of H. pylori flaA- and flaB-negative mutants by electroporation-mediated allelic exchange
1993
Recombinant antigens prepared from the urease subunits of Helicobacter spp.: evidence of protection in a mouse model of gastric infection
1994
Construction and characterization of an isogenic urease-negative mutant of Helicobacter mustelae
1995
Construction of isogenic urease-negative mutants of Helicobacter pylori by allelic exchange
1992