Standout Papers
Citation Impact
Citing Papers
Loss of 53BP1 Causes PARP Inhibitor Resistance in Brca1 -Mutated Mouse Mammary Tumors
2012
Spatially resolved, highly multiplexed RNA profiling in single cells
2015 StandoutScience
Programmable RNA recognition using a CRISPR-associated Argonaute
2018 StandoutNobel
High burden and pervasive positive selection of somatic mutations in normal human skin
2015 StandoutScience
EGFR Variant Heterogeneity in Glioblastoma Resolved through Single-Nucleus Sequencing
2014
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing
2015 Science
fastp: an ultra-fast all-in-one FASTQ preprocessor
2018 Standout
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Evolution of the Cancer Stem Cell Model
2014 Standout
SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing
2012 Standout
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
High-Definition Reconstruction of Clonal Composition in Cancer
2014
Mutational landscape and significance across 12 major cancer types
2013 StandoutNature
Mosaic Amplification of Multiple Receptor Tyrosine Kinase Genes in Glioblastoma
2011
Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders
2011
From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software
2012
Scaling single-cell genomics from phenomenology to mechanism
2017 Nature
Using tumour phylogenetics to identify the roots of metastasis in humans
2015
A view on drug resistance in cancer
2019 StandoutNature
Single-cell sequencing-based technologies will revolutionize whole-organism science
2013
Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
2012 Standout
Single-cell mutational profiling and clonal phylogeny in cancer
2013
Evolution of the cancer genome
2012
Telomeres: history, health, and hallmarks of aging
2021
The biology and management of non-small cell lung cancer
2018 StandoutNature
Lessons from the Cancer Genome
2013
Spatial and Temporal Heterogeneity in High-Grade Serous Ovarian Cancer: A Phylogenetic Analysis
2015
A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity
2015 Nature
Lung Cancer
2008 Standout
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Spatially resolved transcriptomics and beyond
2014
Origins of Metastatic Traits
2013
Unravelling the complexity of metastasis — molecular understanding and targeted therapies
2011
miR-9a Minimizes the Phenotypic Impact of Genomic Diversity by Buffering a Transcription Factor
2013
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
2014 Standout
Complete nitrification by Nitrospira bacteria
2015 StandoutNature
Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing
2013
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Tumor metastasis: moving new biological insights into the clinic
2013
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
Absolute quantification of somatic DNA alterations in human cancer
2012
Every Cell Is Special: Genome-wide Studies Add a New Dimension to Single-Cell Biology
2014
Suppression of lung adenocarcinoma progression by Nkx2-1
2011 Nature
Variable Intra-Tumor Genomic Heterogeneity of Multiple Lesions in Patients With Hepatocellular Carcinoma
2016
Identification of neutral tumor evolution across cancer types
2016
NSAIDs Modulate Clonal Evolution in Barrett's Esophagus
2013
SciClone: Inferring Clonal Architecture and Tracking the Spatial and Temporal Patterns of Tumor Evolution
2014
Insight into the heterogeneity of breast cancer through next-generation sequencing
2011
Intra-tumour heterogeneity: a looking glass for cancer?
2012
Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers
2014 Nature
Sequencing thousands of single-cell genomes with combinatorial indexing
2017
Detecting ultralow-frequency mutations by Duplex Sequencing
2014
Targeting the Adaptability of Heterogeneous Aneuploids
2015
Intratumoral Heterogeneity of the Epigenome
2016
Inferring tumor progression from genomic heterogeneity
2009
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Emerging Biological Principles of Metastasis
2017 Standout
Beyond genome sequencing: Lineage tracking with barcodes to study the dynamics of evolution, infection, and cancer
2014
EMT: 2016
2016 Standout
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
The Complicated Nature of Somatic mtDNA Mutations in Aging
2022
Biological and Therapeutic Impact of Intratumor Heterogeneity in Cancer Evolution
2015
Punctuated copy number evolution and clonal stasis in triple-negative breast cancer
2016
Direct mutation analysis by high-throughput sequencing: From germline to low-abundant, somatic variants
2011
Heterogeneity in breast cancer
2011
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer
2017 Standout
Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain
2012
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells
2015 Standout
Clonal genotype and population structure inference from single-cell tumor sequencing
2016
The role of senescent cells in ageing
2014 StandoutNature
Clonal evolution in cancer
2012 StandoutNature
Tackling the cancer stem cells — what challenges do they pose?
2014
The Hallmarks of Aging
2013 Standout
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Discovery and saturation analysis of cancer genes across 21 tumour types
2014 StandoutNature
Comprehensive Integration of Single-Cell Data
2019 Standout
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
2020 Standout
The first five years of single-cell cancer genomics and beyond
2015
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Tumour heterogeneity and resistance to cancer therapies
2017 Standout
A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis
2015 Nature
Overlooking Evolution: A Systematic Analysis of Cancer Relapse and Therapeutic Resistance Research
2011
Single‐cell sequencing maps gene expression to mutational phylogenies in PDGF ‐ and EGF ‐driven gliomas
2016
Assessing intratumor heterogeneity and tracking longitudinal and spatial clonal evolutionary history by next-generation sequencing
2016
Microfluidic single-cell whole-transcriptome sequencing
2014
Intratumor Heterogeneity: Seeing the Wood for the Trees
2012
Phase diagram of QCD
1998
Cancer chromosomal instability: therapeutic and diagnostic challenges
2012
Metastasis as an evolutionary process
2016 Science
Cancer: Evolution Within a Lifetime
2014
Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer
2017
New Insights into the Troubles of Aneuploidy
2012
Intratumor Heterogeneity: Evolution through Space and Time
2012
Cancer stem cells as ‘units of selection’
2012
Metabolic reprogramming and cancer progression
2020 StandoutScience
Optical computation of a spin glass dynamics with tunable complexity
2021 StandoutNobel
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response
2012
Cancer Genome Landscapes
2013 StandoutScience
Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer
2015
Cell lineage analysis of acute leukemia relapse uncovers the role of replication-rate heterogeneity and microsatellite instability
2012
Deciphering intratumor heterogeneity and temporal acquisition of driver events to refine precision medicine
2014
Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development
2012 StandoutNobel
Microfluidic single cell analysis: from promise to practice
2012
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution
2013
Parallel evolution of tumour subclones mimics diversity between tumours
2013
Static and dynamic critical phenomena at a second order QCD phase transition
1993 StandoutNobel
A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions
2012
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
Works of A. Krasnitz being referenced
Tumour evolution inferred by single-cell sequencing
2011 StandoutNature
QCD with 2 light quark flavours: Thermodynamics on a 163 × 8 lattice and glueballs and topological charge on a 163 × 32 lattice
1993
Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer
2007
QCD thermodynamics with two flavors of Wilson quarks atN t
1992
Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA)
2008