Citation Impact
Citing Papers
Signal transduction and regulation in smooth muscle
1994 StandoutNature
On the relationship between folding and chemical landscapes in enzyme catalysis
2008 StandoutNobel
Origins of coevolution between residues distant in protein 3D structures
2017 StandoutNobel
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions
2011 StandoutNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
QM/MM Methods for Biomolecular Systems
2009 Standout
Comparison of X-ray and NMR structures for the Antennapedia homeodomain–DNA complex
1998
The Role of POU Domain Proteins in the Regulation of Mammalian Pituitary and Nervous System Development
1999
The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain.
1995
The solution structure of the homeodomain of the rat insulin-gene enhancer protein Isl-1. Comparison with other homeodomains 1 1Edited by A. R. Fersht
1999
Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules
1994
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
2007 StandoutNobel
A Genomic and Functional Inventory of Deubiquitinating Enzymes
2005 Standout
Engineering an allosteric transcription factor to respond to new ligands
2015 StandoutNobel
Conversion of the substrate specificity of mouse proteinase granzyme B
1994
Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold – A Potential Therapeutic Intervention for Skin Diseases
2016 StandoutNobel
Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4
1998 Standout
Mutational Analysis of Motor Proteins
1996
Solution structure of the POU-specific DNA-binding domain of Oct-1
1993 Nature
POU domain family values: flexibility, partnerships, and developmental codes.
1997
Interactions with Aromatic Rings in Chemical and Biological Recognition
2003 Standout
The 65 and 110 kDa SR-related proteins of the U4/U6U5 tri-snRNP are essential for the assembly of mature spliceosomes
2001
Trypsin complexed with α1‐proteinase inhibitor has an increased structural flexibility
1995
Simultaneous and coupled energy optimization of homologous proteins: a new tool for structure prediction
1997
Homeodomain-DNA recognition
1994 StandoutNobel
Structural basis of substrate specificity in the serine proteases
1995
Conformational Changes of the BS2 Operator DNA upon Complex Formation with the Antennapedia Homeodomain Studied by NMR with13C/15N-labeled DNA
1999 StandoutNobel
Dynamic measurement of myosin light-chain-domain tilt and twist in muscle contraction
1999 Nature
Structural characterization of a dynein motor domain
1998 StandoutNobel
Evolutionarily conserved networks of residues mediate allosteric communication in proteins
2002
Dynamic protein–DNA recognition: beyond what can be seen
2011
Mechanisms for Flexibility in DNA Sequence Recognition and VP16-Induced Complex Formation by the Oct-1 POU Domain
1995
Activity of the Caenorhabditis elegans UNC-86 POU transcription factor modulates olfactory sensitivity
2003 StandoutNobel
On the Relationship between Thermal Stability and Catalytic Power of Enzymes
2007 StandoutNobel
The DNA binding specificity of the bipartite POU domain and its subdomains.
1992
Serpin Structure, Mechanism, and Function
2002 Standout
Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors
2016
Electrostatic Contributions to Binding of Transition State Analogues Can Be Very Different from the Corresponding Contributions to Catalysis: Phenolates Binding to the Oxyanion Hole of Ketosteroid Isomerase
2007 StandoutNobel
Ketosteroid isomerase provides further support for the idea that enzymes work by electrostatic preorganization
2010 StandoutNobel
A new paradigm for electrostatic catalysis of radical reactions in vitamin B 12 enzymes
2007 StandoutNobel
Targeted mutations in the Caenorhabditis elegans POU homeo box gene ceh-18 cause defects in oocyte cell cycle arrest, gonad migration, and epidermal differentiation.
1994 StandoutNobel
Regulation of touch receptor differentiation by the Caenorhabditis elegans mec-3 and unc-86 genes
1998 StandoutNobel
Serine Protease Mechanism and Specificity
2002
A Computational Study of the Hydrolysis of dGTP Analogues with Halomethylene-Modified Leaving Groups in Solution: Implications for the Mechanism of DNA Polymerases
2009 StandoutNobel
VP16-activation of the C. elegans neural specification transcription factor UNC-86 suppresses mutations in downstream genes and causes defects in neural migration and axon outgrowth
1997 StandoutNobel
Proposed three-dimensional structure for the cellular prion protein.
1994 StandoutNobel
Fluorescence polarization of green fluorescence protein
2002 StandoutNobel
Neuronal Expression of the 5HT3Serotonin Receptor Gene Requires Nuclear Factor 1 Complexes
1998 StandoutNobel
Implicit Solvation Models: Equilibria, Structure, Spectra, and Dynamics
1999 Standout
Protein Ligands to Hur Modulate Its Interaction with Target Mrnas in Vivo
2000
Regulation of ectodermal and excretory function by the C. elegans POU homeobox gene ceh-6
2001 StandoutNobel
Solvent effect theories: Quantum and classical formalisms and their applications in chemistry and biochemistry
1992
Improved recognition of native-like protein structures using a family of designed sequences
2002 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
TheC. elegansPOU-domain transcription factor UNC-86 regulates thetph-1tryptophan hydroxylase gene and neurite outgrowth in specific serotonergic neurons
2002 StandoutNobel
Toward Accurate Screening in Computer-Aided Enzyme Design
2009 StandoutNobel
A Field Guide to Foldamers
2001 Standout
Electrostatic Origin of the Catalytic Effect of a Supramolecular Host Catalyst
2012 StandoutNobel
Origin of the Temperature Dependence of Isotope Effects in Enzymatic Reactions: The Case of Dihydrofolate Reductase
2007 StandoutNobel
The molecular anatomy of caldesmon
1991
Caldesmon, a novel regulatory protein in smooth muscle and nonmuscle actomyosin systems
1991
Catalytic Mechanism and Performance of Computationally Designed Enzymes for Kemp Elimination
2008 StandoutNobel
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Simulation of Tunneling in Enzyme Catalysis by Combining a Biased Propagation Approach and the Quantum Classical Path Method: Application to Lipoxygenase
2007 StandoutNobel
De Novo Determination of Protein Backbone Structure from Residual Dipolar Couplings Using Rosetta
2002 StandoutNobel
Challenges and Advances in Validating Enzyme Design Proposals: The Case of Kemp Eliminase Catalysis
2011 StandoutNobel
Enzyme millisecond conformational dynamics do not catalyze the chemical step
2009 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Hydration structure of the α-chymotrypsin substrate binding pocket: the impact of constrained geometry
2000
Converting Trypsin to Chymotrypsin: The Role of Surface Loops
1992 Science
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII
2001 StandoutNobel
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
The Catalytic Effect of Dihydrofolate Reductase and Its Mutants Is Determined by Reorganization Energies
2007 StandoutNobel
Exploring challenges in rational enzyme design by simulating the catalysis in artificial kemp eliminase
2010 StandoutNobel
Works of A Jancsó being referenced
Mapping Critical Residues in Eukaryotic DNA-Binding Proteins: A Plasmid-Based Genetic Selection Strategy with Application to the Oct-2 POU Motif
1994
An Invariant Asparagine in the POU-Specific Homeodomain Regulates the Specificity of the Oct-2 POU Motif
1994
Modification of acidic residues normalizes sodium dodecyl sulfate-polyacrylamide gel electrophoresis of caldesmon and other proteins that migrate anomalously
1992
Solution Structure of a POU-Specific Homeodomain: 3D-NMR Studies of Human B-Cell Transcription Factor Oct-2
1994
Caldesmon from rabbit liver: Molecular weight and length by analytical ultracentrifugation
1990
Biochemical characterization of the Oct-2 POU domain with implications for bipartite DNA recognition
1992
Regulation of scallop myosin by the regulatory light chain depends on a single glycine residue.
1994
An altered-specificity mutation in a human POU domain demonstrates functional analogy between the POU-specific subdomain and phage lambda repressor.
1994
Electrostatic complementarity within the substrate-binding pocket of trypsin.
1988