Citation Impact
Citing Papers
The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation
2002 StandoutScienceNobel
The Life Span Determinant p66Shc Localizes to Mitochondria Where It Associates with Mitochondrial Heat Shock Protein 70 and Regulates Trans-membrane Potential
2004
Proteasome Activation Occurs at an Early, Premitochondrial Step of Thymocyte Apoptosis
1998
Activators and target genes of Rel/NF-κB transcription factors
1999 Standout
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
2000
Bax-induced Caspase Activation and Apoptosis via Cytochromec Release from Mitochondria Is Inhibitable by Bcl-xL
1999
PK11195, a Ligand of the Mitochondrial Benzodiazepine Receptor, Facilitates the Induction of Apoptosis and Reverses Bcl-2-Mediated Cytoprotection
1998
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
1998 Standout
Reduced Mitochondrial Membrane Potential and Altered Responsiveness of a Mitochondrial Membrane Megachannel in p53-Induced Senescence
1999
The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism
1999
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
2008 StandoutNature
Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization
1999
Methods for the assessment of mitochondrial membrane permeabilization in apoptosis
2007
Mitochondrial permeability transition as a novel principle of hepatorenal toxicity in vivo
2002
Mitochondrial control of apoptosis
1997
Palmitate induces apoptosis via a direct effect on mitochondria
1999
Reactive oxygen intermediates as mediators of programmed cell death in plants and animals
1999
Arsenite Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore
1999
Cell death regulation by the Bcl‐2 protein family in the mitochondria
2003
Target Cell Lysis by CTL Granule Exocytosis Is Independent of ICE/Ced-3 Family Proteases
1997
IκB-α, the NF-κB Inhibitory Subunit, Interacts with ANT, the Mitochondrial ATP/ADP Translocator
2001
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
Bcl-2-family proteins: the role of the BH3 domain in apoptosis
1998
Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation
1999
tcBid promotes Ca2+ signal propagation to the mitochondria: control of Ca2+ permeation through the outer mitochondrial membrane
2002
The Hallmarks of Cancer
2000 Standout
Expression of Vascular Endothelial Growth Factor Receptor 1 in Bone Marrow-derived Mesenchymal Cells Is Dependent on Hypoxia-inducible Factor 1
2006 StandoutNobel
Cell Death
2004 Standout
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
2005 StandoutNature
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
2012 Standout
The biochemistry of apoptosis
2000 StandoutNature
Collapse of the Inner Mitochondrial Transmembrane Potential Is Not Required for Apoptosis of HL60 Cells
1999
Mitochondria, Oxidants, and Aging
2005 Standout
Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator
2000
Apop-1, a Novel Protein Inducing Cyclophilin D-dependent but Bax/Bak-related Channel-independent Apoptosis
2006 StandoutNobel
Bcl-2 and the Outer Mitochondrial Membrane in the Inactivation of Cytochrome c during Fas-mediated Apoptosis
1997
Disruption of Mitochondrial Function during Apoptosis Is Mediated by Caspase Cleavage of the p75 Subunit of Complex I of the Electron Transport Chain
2004
PU.1 and Interferon Consensus Sequence-binding Protein Regulate the Myeloid Expression of the Human Toll-like Receptor 4 Gene
2000 StandoutNobel
Granzyme A Induces Caspase-Independent Mitochondrial Damage, a Required First Step for Apoptosis
2005
Apoptosis
2002 Standout
Release of Cytochrome c from Liver Mitochondria during Permeability Transition
1997
Two CD95 (APO-1/Fas) signaling pathways
1998 Standout
Bacterial Lipopolysaccharide Activates Nuclear Factor-κB through Interleukin-1 Signaling Mediators in Cultured Human Dermal Endothelial Cells and Mononuclear Phagocytes
1999
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event
2001
Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors
1998 Standout
A model for p53-induced apoptosis
1997 StandoutNature
Bcl‐2 family: Life‐or‐death switch
2000
Complement
2001 Standout
Import and processing of heart mitochondrial cyclophilin D
1999
Mitochondria
2003
Molecular characterization of mitochondrial apoptosis-inducing factor
1999 StandoutNature
Complement receptors in HIV infection
1997
Activation of Mitochondria and Release of Mitochondrial Apoptogenic Factors by Betulinic Acid
1998
The Hallmarks of Aging
2013 Standout
Resveratrol-induced apoptosis is enhanced in acute lymphoblastic leukemia cells by modulation of the mitochondrial permeability transition pore
2005
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
Origin of eukaryotic programmed cell death: A consequence of aerobic metabolism?
1997
The TNF and TNF Receptor Superfamilies
2001 Standout
VDAC regulation by the Bcl-2 family of proteins
2000
The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy
1997
Role of Reactive Oxygen Species and p53 in Chromium(VI)-induced Apoptosis
1999 Standout
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
1999 StandoutNature
Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis
2000
The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene
1999 StandoutNobel
Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore
1999
Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution
1997
Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2
1998 StandoutNobel
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
2001 StandoutScience
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
The Pathophysiology of Mitochondrial Cell Death
2004 StandoutScience
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Nanoscale distribution of mitochondrial import receptor Tom20 is adjusted to cellular conditions and exhibits an inner-cellular gradient
2011 StandoutNobel
Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway
2000 StandoutScience
Heat stress prevents mitochondrial injury in ATP-depleted renal epithelial cells
2002
Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked
1997 StandoutScience
The mitochondrial permeability transition pore and its role in cell death
1999 Standout
Biochemical Pathways of Caspase Activation During Apoptosis
1999 Standout
Mitochondrial Diseases in Man and Mouse
1999 StandoutScience
The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins
1998
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Vaccinia Virus F1L Protein Is a Tail-Anchored Protein That Functions at the Mitochondria To Inhibit Apoptosis
2004
The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis
1997 StandoutScience
Toll-related receptors and the control of antimicrobial peptide expression inDrosophila
2000 StandoutNobel
Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
2000 StandoutScience
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
2000
VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release
2001
Mitochondria and Apoptosis
1998 StandoutScience
Decoding the Patterns of Self and Nonself by the Innate Immune System
2002 StandoutScience
Purified Photoproducts of Merocyanine 540 Trigger Cytochrome C Release and Caspase 8-Dependent Apoptosis in Human Leukemia and Melanoma Cells
1999
MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment
1999
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.
1996
THE MITOCHONDRIAL DEATH/LIFE REGULATOR IN APOPTOSIS AND NECROSIS
1998 Standout
The Cyclin-dependent Kinase Cdk2 Regulates Thymocyte Apoptosis
1999
The Mitochondrion in Cell Death Control: Certainties and Incognita
2000
The Central Executioner of Apoptosis: Multiple Connections between Protease Activation and Mitochondria in Fas/APO-1/CD95- and Ceramide-induced Apoptosis
1997
Inhibition of Bax Channel-Forming Activity by Bcl-2
1997 Science
Mitochondrial permeability transition in apoptosis and necrosis
2005
Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms
1999 StandoutScience
Clinically Approved Heterocyclics Act on a Mitochondrial Target and Reduce Stroke-induced Pathology
2004
The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus.
1999
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Phytosphingosine in combination with ionizing radiation enhances apoptotic cell death in radiation-resistant cancer cells through ROS-dependent and -independent AIF release
2004
Caspases: Enemies Within
1998 StandoutScience
Intracellular Bax Translocation after Transient Cerebral Ischemia: Implications for a Role of the Mitochondrial Apoptotic Signaling Pathway in Ischemic Neuronal Death
2001
Cyclosporin A, But Not FK 506, Protects Mitochondria and Neurons against Hypoglycemic Damage and Implicates the Mitochondrial Permeability Transition in Cell Death
1998
Bax-induced Cytochrome C Release from Mitochondria Is Independent of the Permeability Transition Pore but Highly Dependent on Mg2+ Ions
1998
Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis
2004 StandoutScience
Works of A Haeffner being referenced
Growth hormone prevents human monocytic cells from Fas-mediated apoptosis by up-regulating Bcl-2 expression
1999
Mitochondrial permeability transition is a central coordinating event of apoptosis.
1996
Triggering of complement receptors CR1 (CD35) and CR3 (CD11b/CD18) induces nuclear translocation of NF-kappa B (p50/p65) in human monocytes and enhances viral replication in HIV-infected monocytic cells.
1995
Inhibitory effect of growth hormone on TNF-alpha secretion and nuclear factor-kappaB translocation in lipopolysaccharide-stimulated human monocytes.
1997