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Citing Papers
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
The Antinociceptive and Sedative Effects of Carbachol and Oxycodone Administered into Brainstem Pontine Reticular Formation and Spinal Subarachnoid Space in Rats
2001
M1 Receptor Agonist Activity Is Not a Requirement for Muscarinic Antinociception
1997
Development of Muscarinic Analgesics Derived from Epibatidine: Role of the M4 Receptor Subtype
1999
Monocyte Chemotactic Protein–1 As A Chemoattractant for Human Hepatic Stellate Cells
1999
Antifibrogenic effects of canrenone, an antialdosteronic drug, on human hepatic stellate cells
2003
Physiologic concentrations of leptin increase collagen production by non-immortalized human hepatic stellate cells
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In Vitro And In Vivo Activation of Rat Hepatic Stellate Cells Results In De Novo Expression of L–Type Voltage–Operated Calcium Channels
2001
Biological Effects of C-type Natriuretic Peptide in Human Myofibroblastic Hepatic Stellate Cells
1999
Molecular basis for calcium signaling in hepatic stellate cells
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Chloride channel regulation in the skeletal muscle of normal and myotonic goats
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The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C1 1The authors thank Wanda Delogu and Nadia Navari for skillful technical help, Dr. Roberto G. Romanelli for help in collecting liver biopsy specimens, and Dr. Mario Strazzabosco (Ospedali Riuniti di Bergamo, Italy) for providing part of the tissue samples with primary biliary cirrhosis.
2003
Evidence for hypernociception induction following histamine H1 receptor activation in rodents
1998
PDGF and signal transduction in hepatic stellate cells
2002
Liver fibrosis
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Liver fibrosis
2000
Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice
1999 StandoutNobel
The Cellular Basis of Hepatic Fibrosis -- Mechanisms and Treatment Strategies
1993
Impact of oestrogens on the progression of liver disease
2003
Morphological study of endothelin-1-induced contraction of cultured hepatic stellate cells on hydrated collagen gels
1996
Cell adhesion regulates platelet-derived growth factor-induced MAP kinase and PI-3 kinase activation in stellate cells
2002
Descending control of pain
2002 Standout
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
5-HT1A Agonists Induce Central Cholinergic Antinociception
1997
Expression of somatostatin receptors in normal and cirrhotic human liver and in hepatocellular carcinoma
2004
Defects in cGMP-PKG pathway contribute to impaired NO-dependent responses in hepatic stellate cells upon activation
2005
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Expression of Interleukin-10 by in Vitro and in Vivo Activated Hepatic Stellate Cells
1998
Usefulness of Taurine in Chronic Congestive Heart Failure and Its Prospective Application.
1992
Antihistamines as analgesics
2001
Tight junction proteins1This review is dedicated to the memory of Thomas Kreis.1
1998
Multifunctional strands in tight junctions
2001 Standout
Transformation-dependent calcium influx by voltage-operated calcium channels in stellate cells of rat liver
1999
Angiotensin II induces contraction and proliferation of human hepatic stellate cells
2000
Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice
2007 StandoutNobel
Expression of the thrombin receptor in human liver: Up-regulation during acute and chronic injury
1998
Oxidative Stress And Potassium Channel Function
2002
Lignocaine selectively reduces C fibre-evoked neuronal activity in rat spinal cord in vitro by decreasing N -methyl-D-aspartate and neurokinin receptor-mediated post-synaptic depolarizations; implications for the development of novel centrally acting analgesics
1996
β2‐Adrenergic receptor overexpression in the developing mouse heart: evidence for targeted modulation of ion channels
1999 StandoutNobel
The tachykinin NK1 receptor. Part II: Distribution and pathophysiological roles
1998
Delayed Induction, Not Impaired Recruitment, of Specific CD8+ T Cells Causes the Late Onset of Acute Hepatitis C
2011 StandoutNobel
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
GABAB Receptors: A New Paradigm in G Protein Signaling
2000
The Role of α1β1 Integrin in Wound Contraction
1997
Hepatic stellate cells and the regulation of liver inflammation
1999
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Evidence for a novel natriuretic peptide receptor that prefers brain natriuretic peptide over atrial natriuretic peptide
2001 StandoutNobel
Role of oxidative stress in cardiovascular diseases
2000
Comparison of the Effects of Intraventricular Taurine, GABA and Homotaurine on Serum Prolactin Levels in Male Rats
1989
Caffeine induces central cholinergic analgesia
1997
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Regulation of PDGF and its receptors in fibrotic diseases
2004
Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: Endothelial dysfunction in portal hypertension
1998
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
2007 Standout
Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension
2002
Activation-dependent contractility of rat hepatic lipocytes in culture and in vivo.
1993
Growth inhibitory properties of endothelin-1 in activated human hepatic stellate cells: a cyclic adenosine monophosphate-mediated pathway. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothelin B receptors.
1996
Molecular Regulation of Hepatic Fibrosis, an Integrated Cellular Response to Tissue Injury
2000 Standout
Mechanisms of Hepatic Fibrogenesis
2008 Standout
Mechanisms of Nitric Oxide Interplay with Rho GTPase Family Members in Modulation of Actin Membrane Dynamics in Pericytes and Fibroblasts
2005
Investigation into the role of histamine receptors in rodent antinociception
1996
Hepatic stellate cells and intralobular innervation in human liver cirrhosis
1997
Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ
2007
Cellular localization of endothelin-1 and increased production in liver injury in the rat: Potential for autocrine and paracrine effects on stellate cells
1998
Differential interaction of plakoglobin and β-catenin with the ubiquitin-proteasome system
2000 StandoutNobel
Expression of Osteopontin in Kupffer Cells and Hepatic Macrophages and Stellate Cells in Rat Liver after Carbon Tetrachloride Intoxication: A Possible Factor for Macrophage Migration into Hepatic Necrotic Areas
1999
Chemotherapy-Induced Nausea and Vomiting
2008 Standout
Effects of a histamine H2 receptor agonist and antagonist on restraint-induced antinociception in female mice
1995
Sinusoidal remodeling and angiogenesis: A new function for the liver-specific pericyte?
2007
Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells
1996
Identification of a Gene Encoding a Hyperpolarization-Activated Pacemaker Channel of Brain
1998 StandoutNobel
GABAB receptors
1995
Studies of hypoxemic/reoxygenation injury: Without aortic clamping:
1995 StandoutNobel
Characterization of Muscarinic Receptor Subtypes That Mediate Antinociception in the Rat Spinal Cord
1997
Involvement of M3 muscarinic receptors of the spinal cord in formalin-induced nociception in mice
2000
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Natriuretic Peptides
1998 Standout
Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators
2004 StandoutNobel
Prognostic importance of atrial natriuretic peptide in patients with chronic heart failure
1989
Signal transduction in hepatic stellate cells
1998
Both Ca2+-dependent and -independent pathways are involved in rat hepatic stellate cell contraction and intrahepatic hyperresponsiveness to methoxamine
2006
Hepatic stellate cells reversibly express α-smooth muscle actin during acute hepatic ischemia
1997
Role of histamine H1 receptor in pain perception: a study of the receptor gene knockout mice
2000
CELLUAR PATHOPHYSIOLOGY OF PORTAL HYPERTENSION AND PROSPECTS FOR MANAGEMENT WITH GENE THERAPY
2001
Biosynthesis of platelet-activating factor and its 1O-acyl analogue by liver fat-storing cells
1994
Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines.
1993
N-Acetylcysteine Induces Cell Cycle Arrest in Hepatic Stellate Cells through Its Reducing Activity
2001
Vascular mediators in the injured liver
2003
A Tripartite Protein Complex with the Potential to Couple Synaptic Vesicle Exocytosis to Cell Adhesion in Brain
1998 StandoutNobel
Expression of neural cell adhesion molecule (N-CAM) in perisinusoidal stellate cells of the human liver
1995
Prolonged antagonism of α1-Adrenergic vasoconstriction in the rat liver by atrial natriuretic peptide
1995
Translating an Understanding of the Pathogenesis of Hepatic Fibrosis to Novel Therapies
2013
Effect of pertussis toxin on morphine, diphenhydramine, baclofen, clomipramine and physostigmine antinociception
1996
The physiology of brain histamine
2001
Role of sodium and calcium channel block in unmasking the Brugada syndrome
2004
Chronic liver injury, TGF-β, and cancer
2001
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Temperature as a dependent variable in the study of cholinergic mechanisms
1988
In vivo pharmacology of butylthio[2.2.2] (LY297802 / NNC11-1053), an orally acting antinociceptive muscarinic agonist
1997
Carbon monoxide: an endogenous modulator of sinusoidal tone in the perfused rat liver.
1995
Nucleotide receptors in hepatic stellate cells of the rat
1994
[Ca2+]i-independent contractile force generation by rat hepatic stellate cells in response to endothelin-1
2005
Detection of Cytochrome P4503A (CYP3A) in Human Hepatic Stellate Cells
1997
Some Aspects of the Biological Role of Adenosine 3',5'-monophosphate (Cyclic AMP)
1968 StandoutNobel
Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2.
1993
ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult
2005 Standout
Hyperactivity and Intact Hippocampus-Dependent Learning in Mice Lacking the M1Muscarinic Acetylcholine Receptor
2001
Dispersion of refractoriness in canine ventricular myocardium. Effects of sympathetic stimulation.
1991
Atrial natriuretic peptide antagonizes endothelin-induced calcium increase and cell contraction in cultured human hepatic stellate cells
1999
Ca2+ and Rho Signaling Pathways: Two Paths to Hepatic Stellate Cell Contraction
2001
Sensitization to anaphylaxis and to some of its pharmacological mediators by blockade of the beta adrenergic receptors
1967
Apical junctions and cell signalling in epithelia
1993
Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the Studies of Left Ventricular Dysfunction (SOLVD).
1990 Standout
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
The ionic basis of concentration‐related effects of noradrenaline on the action potential of calf cardiac purkinje fibres.
1982
PDGF and signal transduction in hepatic stellate cells
2002
Liver nbsp fibrosis signals leading to the amplification of the fibrogenic hepatic stellate cell
2003
Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia
1997 StandoutNobel
The time course of the effects of ?-and ?-adrenoceptor stimulation by isoprenaline and methoxamine on the contractile force and cAMP level of the isolated rabbit papillary muscle
1975
Thrombin stimulates proliferation of liver fat-storing cells and expression of monocyte chemotactic protein-1: Potential role in liver injury*1
1995
STUDIES ON THE POSITIVE INOTROPIC EFFECT OF PHENYLEPHRINE: A COMPARISON WITH ISOPRENALINE
1975
GABA and its receptors in the spinal cord
1996
Thrombin stimulates proliferation of liver fat-storing cells and expression of monocyte chemotactic protein-1: Potential role in liver injury
1995
Atrial Fibrillation Begets Atrial Fibrillation
1995 Standout
Novel Qualitative Structure-Activity Relationships for the Antinociceptive Actions of H2 Antagonists, H3Antagonists and Derivatives
1997
Effects of Epinephrine on the Pacemaker Potassium Current of Cardiac Purkinje Fibers
1974
Two novel antifibrotics, HOE 077 and Safironil, modulate stellate cell activation in rat liver injury: differential effects in males and females.
1998
Brugada Syndrome: Report of the Second Consensus Conference
2005 Standout
Putative mechanism of hypotensive action of platelet-activating factor in dogs.
1992 StandoutNobel
Vasoactive effect of endothelin-1 on rat liver in vivo
1994
The Caenorhabditis elegans lim-6 LIM homeobox gene regulates neurite outgrowth and function of particular GABAergic neurons
1999 StandoutNobel
Fiber Types in Mammalian Skeletal Muscles
2011 Standout
Effects of ethanol on prostanoid production by liver fat-storing cells.
1993
Modulation of the delayed rectifier K+ current by isoprenaline in bull‐frog atrial myocytes.
1989
Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin
2005 StandoutScienceNobel
Effects of ethanol on prostanoid production by liver fat-storing cells
1993
Interaction of reactive oxygen species with ion transport mechanisms
1998
The molecular organization of tight junctions.
1993
Binding of Neuroligins to PSD-95
1997 StandoutScienceNobel
The pattern of cardiovascular alterations induced by infusion of platelet-activating factor in rabbit is modified by pretreatment with H1-H2 receptor antagonists but not by cyclooxygenase inhibition
1987
Liver fibrosis
1999
THE ACTIONS OF LEUKOTRIENES C4 AND D4 ON GUINEA‐PIG ISOLATED HEARTS
1982
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
Retinoic acid suppresses the response to platelet-derived growth factor in human hepatic Ito-cell-like myofibroblasts: a post-receptor mechanism independent of raf/fos/jun/egr activation
1993
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
The Cellular Pathogenesis of Portal Hypertension: Stellate Cell Contractility, Endothelin, and Nitric Oxide
1997
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
A model system for cell adhesion and signal transduction in Drosophila
1993
α-Adrenoceptors in the ventricular myocardium: clonidine, naphazoline and methoxamine as partial α-agonists exerting a competitive dualism in action to phenylephrine
1976
Transforming growth factor-β1 regulates platelet-derived growth factor receptor β subunit in human liver fat-storing cells
1995
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects
1987 StandoutScienceNobel
Quantitation of rat hepatic stellate cell contraction: stellate cells’ contribution to sinusoidal resistance
1999
Alpha-adrenergic receptors in rat myocardium. Identification by binding of [3H]dihydroergocryptine.
1978 StandoutNobel
Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8
1996
Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver.
1994
Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their Significance in Germ Cell Movement in the Seminiferous Epithelium during Spermatogenesis
2004 Standout
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
2011 StandoutNobel
Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility, Pharmaceutical and Biomedical Applications
2012 Standout
Expression of the Na + /Ca 2+ exchanger emerges in hepatic stellate cells after activation in association with liver fibrosis
1998
Chronic ethanol consumption increases hepatic sinusoidal contractile response to endothelin-1 in the rat
1995
Prostaglandin F2α and D2 Release From Primary Ito Cell Cultures After Stimulation With Noradrenaline and Atp But Not Adenosine
1994
Immunohistochemical demonstration of GABAergic neurons in the enteric nervous system
1986
Role of hepatic stellate cells in the pathogenesis of portal hypertension.
2002
Localization and differential expression of two isoforms of the tight junction protein ZO-1
1992
Occludin: a novel integral membrane protein localizing at tight junctions.
1993 Standout
Why are there so many adrenoceptor subtypes?
1994
Characterization of the hyperpolarization‐activated current, I(f), in ventricular myocytes isolated from hypertensive rats.
1994
Endothelin receptors in rat liver: lipocytes as a contractile target for endothelin 1.
1993
Works of A Giotti being referenced
The action of taurine on chloride conductance and excitability characteristics of rat striated muscle fibers
1987
Desensitization of GABAB receptors and antagonism by CGP 35348, prevent bicuculline- and picrotoxin-induced antinociception
1992
The effects of taurine on pharmacologically induced myotonia
1989
Role of muscarinic receptor subtypes in central antinociception
1992
Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transients.
1992
Investigation into atropine‐induced antinociception
1990
CGP 35348, a new GABAB antagonist, prevents antinociception and muscle‐relaxant effect induced by baclofen
1991
Role of histamine in rodent antinociception
1994
Antinociception induced by systemic administration of local anaesthetics depends on a central cholinergic mechanism
1987
Tachykinins activate guinea‐pig alveolar macrophages: involvement of NK2 and NK1 receptors
1990
Central muscarinic analgesia is mediated by M1 receptors
1990
[3H]-nitrendipine binding in membranes obtained from hypoxic and reoxygenated heart
1987
Effects of noradrenaline and isoprenaline, in combination with α‐ and β‐receptor blocking substances, on the action potential of cardiac Purkinje fibres
1973
Cellular electrophysiological basis for oxygen radical-induced arrhythmias. A patch-clamp study in guinea pig ventricular myocytes.
1991
Effect of taurine on calcium levels and contractility in guinea-pig ventricular strips
1982
Cardiac hypoxia and subsequent reoxygenation: sensitivity to L‐arginine methylester
1986
Cingulin, a specific protein component of tight junctions, is expressed in normal and neoplastic human epithelial tissues.
1991
Antiarrhythmic actions of antihistamines
1976
Potentiation by taurine of inotropic effect of strophanthin-K on guinea-pig isolated auricles
1971
The mitogenic effect of platelet-derived growth factor in human hepatic stellate cells requires calcium influx
1995
Effects of adrenotropic drugs on the release of histamine in the anaphylactic reaction of the isolated guinea pig heart
1964
GABAA and GABAB receptor‐mediated effects in guinea‐pig ileum
1983
The influences of adrenolytic drugs and noradrenaline on the histamine release in cardiac anaphylaxis in vitro
1966
Homotaurine and muscimol mimic taurine and gaba effects on muscle tone and temperature regulation
1978
Modulatory activity of GABAB receptors on cholinergic tone in guinea‐pig distal colon
1985
Homotaurine: a GABAB antagonist in guinea‐pig ileum
1983
Antihistaminic antinociception: Research about mechanism of action
1988