Citation Impact
Citing Papers
Persistent epigenetic differences associated with prenatal exposure to famine in humans
2008 Standout
Zinc Finger-DNA Recognition: Crystal Structure of a Zif268-DNA Complex at 2.1 Å
1991 StandoutScience
Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis
2012 StandoutNobel
Phenotypic plasticity and the epigenetics of human disease
2007 Nature
Minireview: Tissue-SpecificVersusGeneralized Gene Targeting of theigf1andigf1rGenes and Their Roles in Insulin-Like Growth Factor Physiology
2001
Effects of an Rb mutation in the mouse
1992 StandoutNature
Disruption of insulin–like growth factor 2 imprinting in Beckwith–Wiedemann syndrome
1993
The Genetics of Wilms' Tumor
1992
The history of cancer epigenetics
2004 Standout
A tumor chromosome rearrangement further defines the 11p13 Wilms tumor locus
1991
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
1996 Standout
Modular regulatory principles of large non-coding RNAs
2012 StandoutNature
Monoallelic expression of the human H19 gene
1992
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
WT-1 is required for early kidney development
1993 Standout
An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor
1990
Relaxation of imprinted genes in human cancer
1993 Nature
Physical linkage of two mammalian imprinted genes, H19 and insulin–like growth factor 2
1992
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Allele-specific replication timing of imprinted gene regions
1993 Nature
The H19 Transcript Is Associated with Polysomes and May Regulate IGF2 Expression in trans
1998
Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith–Wiedemann and Simpson–Golabi–Behmel syndromes
1997
DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms
2002
APC mutations occur early during colorectal tumorigenesis
1992 StandoutNature
Further Localization of the Genefor Hereditary Paragangliomasand Evidence for Linkage inUnrelated Families
1994
Lessons from Hereditary Colorectal Cancer
1996 Standout
The Epigenomics of Cancer
2007 Standout
Tumor suppressor genes
1991 Standout
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
1993 Standout
Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping
1990 StandoutNature
Epigenetics in Cancer
2008 Standout
Genetics and Epigenetics of the Multifunctional Protein CTCF
2007
Epigenetics in cancer
2009 Standout
Global loss of imprinting leads to widespread tumorigenesis in adult mice
2005
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
2000 StandoutNature
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
2002 StandoutNobel
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Disruption of a Novel Imprinted Zinc-Finger Gene, ZNF215, in Beckwith-Wiedemann Syndrome
2000
Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
1991 StandoutNature
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
2002 Nature
Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour
1994
Gene Silencing in Cancer in Association with Promoter Hypermethylation
2003 Standout
The fission yeast gene pmt1+encodes a DNA methyltransferase homologue
1995 StandoutNobel
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Oncogenes and signal transduction
1991 Standout
Highly Integrated Single-Base Resolution Maps of the Epigenome in Arabidopsis
2008 Standout
Molecular themes in oncogenesis
1991 StandoutNobel
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1992 StandoutNature
Allelotype of head and neck paragangliomas: Allelic imbalance is confined to the long arm of chromosome 11, the site of the predisposing locus PGL
1994
The Polycomb group protein EZH2 directly controls DNA methylation
2005 StandoutNature
Deregulation of both imprinted and expressed alleles of the insulin–like growth factor 2 gene during β–cell tumorigenesis
1995
Parental imprinting of autosomal mammalian genes
1994
Accumulated allelic losses in the development of invasive urothelial cancer
1993 StandoutNobel
Allelic inactivation regulates olfactory receptor gene expression
1994 StandoutNobel
Differential Effects of Culture on Imprinted H19 Expression in the Preimplantation Mouse Embryo1
2000
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
2007 StandoutNature
Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
1993 Standout
Effect of In Utero and Early-Life Conditions on Adult Health and Disease
2008 Standout
CTCF: Master Weaver of the Genome
2009 Standout
Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome
1991
A catalogue of imprinted genes and parent-of-origin effects in humans and animals
1998
Methylation Sequencing Analysis Refines the Region ofH19 Epimutation in Wilms Tumor
1999
A gene for Wilms tumour?
1990 Nature
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
1993 Standout
Antioncogenes and human cancer.
1993
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
1990 Standout
Tumor Suppressor Genes
1991 Science
The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc
1996 StandoutScience
Loss of Imprinting ofIGF2: A Common Epigenetic Modifier of Intestinal Tumor Risk
2005
Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development.
1991
Epigenetic changes at the insulin-like growth factor II/ H19 locus in developing kidney is an early event in Wilms tumorigenesis
1997
Type 1 Neurofibromatosis Gene: Identification of a Large Transcript Disrupted in Three NF1 Patients
1990 StandoutScience
Cancer Genome Landscapes
2013 StandoutScience
Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis.
1996
Brca2 is required for embryonic cellular proliferation in the mouse.
1997 StandoutNobel
Genomic analysis of orthologous mouse and human olfactory receptor loci
2001 StandoutNobel
A Mouse Model of the Aniridia-Wilms Tumor Deletion Syndrome
1990 Science
Effects of DNA methylation on topoisomerase I and II cleavage activities.
1994 StandoutNobel
CpG island methylator phenotype in colorectal cancer
1999 Standout
The Complete Nucleotide Sequence of the Human Immunoglobulin Heavy Chain Variable Region Locus
1998 StandoutNobel
Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
2000 StandoutScience
CTCF Regulates Allelic Expression of Igf2 by Orchestrating a Promoter-Polycomb Repressive Complex 2 Intrachromosomal Loop
2008
Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms tumor.
1995
Epigenetic mechanisms underlying the imprinting of the mouse H19 gene.
1993 StandoutNobel
DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1
1996 StandoutScience
Works of A E Reeve being referenced
Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour
1993 Nature
Constitutional relaxation of insulin–like growth factor II gene imprinting associated with Wilms' tumour and gigantism
1993
Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells.
1989
Genetic linkage of Beckwith-Wiedemann syndrome to 11p15.
1989