Citation Impact
Citing Papers
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
The Glutathione Status of Cells
1978
Improvement of a Potential Anthrax Therapeutic by Computational Protein Design
2011 StandoutNobel
A Family of Basic Amino Acid Transporters of the Vacuolar Membrane from Saccharomyces cerevisiae
2004 StandoutNobel
Targeted Disruption of the Cln3 Gene Provides a Mouse Model for Batten Disease
1999
Beyond Cholesterol
1989 Standout
Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith–Wiedemann and Simpson–Golabi–Behmel syndromes
1997
Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice
2003
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Cytosolic lipolysis and lipophagy: two sides of the same coin
2017
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
2000 StandoutNature
Participation of Autophagy in Storage of Lysosomes in Neurons from Mouse Models of Neuronal Ceroid-Lipofuscinoses (Batten Disease)
2005
Normal amino acid uptake by cultured human fibroblasts does not require gamma-glutamyl transpeptidase
1976
Autophagy in the Pathogenesis of Disease
2008 Standout
RPE lipofuscin and its role in retinal pathobiology
2005
Loss of autophagy in the central nervous system causes neurodegeneration in mice
2006 StandoutNature
A mutation in the tRNALeu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies
1990 StandoutNature
Batten's disease: Clues to neuronal protein catabolism in lysosomes
2000
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The role of glutathione in cancer
2004
Coated pits, coated vesicles, and receptor-mediated endocytosis
1979 StandoutNatureNobel
Demonstration of low density lipoprotein receptors in mouse teratocarcinoma stem cells and description of a method for producing receptor-deficient mutant mice
1979 StandoutNobel
Disorders of Glutamate Metabolism and Neurological Dysfunction
1981 StandoutNobel
Genetics of the LDL receptor: Evidence that the mutations affecting binding and internalization are allelic
1977 StandoutNobel
a-1,4-glucan: a-1,4-glucan 6-glycosyltransferase from liver
1962
Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine
1980 Standout
Myoclonus epilepsy associated with ragged-red fibres (mitochondrial abnormalities): Disease entity or a syndrome?
1980
Localization of low density lipoprotein receptors on plasma membrane of normal human fibroblasts and their absence in cells from a familial hypercholesterolemia homozygote.
1976 StandoutNobel
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Enzyme deficiency in cholesteryl ester storage disease
1972
Immunocytochemical visualization of coated pits and vesicles in human fibroblasts: Relation to low density lipoprotein receptor distribution
1978 StandoutNobel
The fate of extracellular glutathione in the rat☆
1978
Receptor-dependent hydrolysis of cholesteryl esters contained in plasma low density lipoprotein.
1975 StandoutNobel
A role in vacuolar arginine transport for yeast Btn1p and for human CLN3, the protein defective in Batten disease
2003
Evidence for regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol synthesis in nonhepatic tissues of rat.
1976 StandoutNobel
Substrate-binding properties of firefly luciferase
1969
γ-Glutamyl transpeptidase: catalytic, structural and functional aspects
1981
Restoration of a regulatory response to low density lipoprotein in acid lipase-deficient human fibroblasts.
1976
Indications for Marrow Transplantation
1984 StandoutNobel
Demonstration of serum protein differences in cystic fibrosis by isoelectric focusing in thin-layer polyacrylamide gels
1973
Replacement of endogenous cholesteryl esters of low density lipoprotein with exogenous cholesteryl linoleate. Reconstitution of a biologically active lipoprotein particle.
1978 StandoutNobel
Overloading human aortic smooth muscle cells with low density lipoprotein-cholesteryl esters reproduces features of atherosclerosis in vitro.
1977 StandoutNobel
Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals
1987 Standout
Cystine metabolism in human fibroblasts. Comparison of normal, cystinotic, and gamma-glutamylcysteine synethetase-deficient cells.
1976
Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts
1977 StandoutNobel
Solubilization of the low density lipoprotein receptor
1979 StandoutNobel
Gene deletion and restriction fragment length polymorphisms at the human ornithine transcarbamylase locus
1985 Nature
Membrane flow during pinocytosis. A stereologic analysis.
1976 StandoutNobel
Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA
1989 StandoutScience
IN VITRO SYNTHESIS OF PARTICULATE GLYCOGEN
1965 StandoutNobel
A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts
1977 StandoutNatureNobel
Squalene synthetase activity in human fibroblasts: Regulation via the low density lipoprotein receptor
1979 StandoutNobel
Development of Increased Cytoplasmic Binding of Androgen in the Submandibular Gland of the Mouse with Testicular Feminization
1973 StandoutNobel
Evidence for Increased Cytoplasmic Androgen Binding in the Submandibular Gland of the Mouse with Testicular Feminization
1972 StandoutNobel
Heterozygous familial hypercholesterolemia: Failure of normal allele to compensate for mutant allele at a regulated genetic locus
1976 StandoutNobel
Oxidized Redox State of Glutathione in the Endoplasmic Reticulum
1992 StandoutScience
CHOLESTEROL METABOLISM IN THE MACROPHAGE
1972
Inhibition of cholesteryl ester formation in human fibroblasts by an analogue of 7-ketocholesterol and by progesterone
1978 StandoutNobel
Replacement of neutral lipids of low density lipoprotein with esters of long chain unsaturated fatty acids.
1979 StandoutNobel
Deficient Activity of Hepatic Acid Lipase in Cholesterol Ester Storage Disease
1972 Science
Receptor-Mediated Control of Cholesterol Metabolism
1976 StandoutScienceNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.
1976 StandoutNobel
Assay, Kinetics, and Lysosomal Localization of an Acid Cholesteryl Esterase in Rabbit Aortic Smooth Muscle Cells
1974 StandoutNobel
Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
1979 StandoutNobel
THE METABOLISM OF AMINO ACIDS, PEPTIDES, AND DISULFIDES IN LYSOSOMES OF FIBROBLASTS CULTURED FROM NORMAL INDIVIDUALS AND THOSE WITH CYSTINOSIS
1970
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase
1978 StandoutNobel
Receptor-mediated uptake of low density lipoprotein reconstituted with 25-hydroxycholesteryl oleate suppresses 3-hydroxy-3-methylglutaryl-coenzyme A reductase and inhibits growth of human fibroblasts
1978 StandoutNobel
Lipoprotein-mediated regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesteryl ester metabolism in the adrenal gland of the rat.
1977 StandoutNobel
Real-Time Bioluminescence Imaging of Glycans on Live Cells
2010 StandoutNobel
More about X‐linked testicular feminization of the mouse as a noninducible (is) mutation of a regulatory locus: 5α‐androstan‐3α‐17ß‐diol as the true inducer of kidney alcohol dehydrogenase and ß‐glucuronidase
1971
Biologically active low density lipoprotein in human peripheral lymph.
1978 StandoutNobel
Works of A. D. Patrick being referenced
Simpson—Golabi—Behmel syndrome: Disproportionate fetal overgrowth and elevated maternal serum alpha‐fetoprotein
1994
Accumulation of dolichol-linked oligosaccharides in ceroid-lipofuscinosis (Batten disease)
1988
Reversal of clinical features of hurler's disease and biochemical improvement after treatment by bone marrow transplantation
1982
FETAL LIVER BIOPSY FOR PRENATAL DIAGNOSIS OF ORNITHINE CARBAMYL TRANSFERASE DEFICIENCY
1982
Leigh's subacute necrotizing encephalopathy: clinical and biochemical study, with special reference to therapy with lipoate.
1967
Glutathionuria: Inborn error of metabolism due to tissue deficiency of gamma-glutamyl transpeptidase
1975
A Deficiency of Glucocerebrosidase in Gaucher's Disease
1965
Glutathionuria: γ‐Glutamyl transpeptidase deficiency
1979
Lysosomal storage of subunit c of mitochondrial ATP synthase in Batten's disease (ceroid-lipofuscinosis)
1991
Biochemical diagnosis of cystinosis using cultured cells
1974
Cystinosis: electron microscopic evidence of lysosomal storage of cystine in lymph node
1968
Wolman's disease: Deficiency of E600-resistant acid esterase activity with storage of lipids in lysosomes
1970
Deficiency of an Acid Lipase in Wolman's Disease
1969 Nature
Inhibition of the motility of gill cilia of Dreissensia by plasma of cystic fibrosis patients and their parents.
1969
Enzymes of the potato concerned in the synthesis of starch. 1. The separation and crystallization of Q-enzyme
1952