Citation Impact
Citing Papers
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
PROCEEDINGS OF THE BRITISH PHARMACOLOGICAL SOCIETY
1971 StandoutNobel
Catalytic Asymmetric Three‐Component Synthesis of Homoallylic Amines
2013 StandoutNobel
Are poor metabolisers of sparteine/debrisoquine less pain tolerant than extensive metabolisers?
1993
Two novel series of allocolchicinoids with modified seven membered B-rings: design, synthesis, inhibition of tubulin assembly and cytotoxicity
2005
Mapping the Binding Site of Colchicinoids on β-Tubulin
2000
Anti‐mitotic activity of colchicine and the structural basis for its interaction with tubulin
2007
Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials
2007 Standout
Catalytic Asymmetric Conjugate Addition/Oxidative Dearomatization Towards Multifunctional Spirocyclic Compounds
2011 StandoutNobel
Direct Catalytic Asymmetric Enolexo Aldolizations
2003 StandoutNobel
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain
2004 StandoutNature
Myasthenia Gravis
1994 Standout
Phenserine and ring C hetero‐analogues: Drug candidates for the treatment of Alzheimer's disease
1995
A convenient enzymatic synthesis of l-halotryptophans
2006
Fab Antibody Fragments
2004
Catalytic Asymmetric Hydroperoxidation of α,β‐Unsaturated Ketones: An Approach to Enantiopure Peroxyhemiketals, Epoxides, and Aldols
2008 StandoutNobel
Interactions of colchicine with tubulin
1991
Anticancer drug design based on plant-derived natural products
1999
Excitatory Amino Acids as a Final Common Pathway for Neurologic Disorders
1994 Standout
Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists
1991 Nature
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
Peroxy natural products
1992
Seeding “one-dimensional crystallization” of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
1993 Standout
Mammalian Cytochrome P450 Enzymes Catalyze the Phenol-coupling Step in Endogenous Morphine Biosynthesis
2009
Versatile Access to Chiral Indolines by Catalytic Asymmetric Fischer Indolization
2013 StandoutNobel
Asymmetric 1,3-Dipolar Cycloaddition Reactions
1998 Standout
Nickel-phosphine complex-catalyzed Grignard coupling—II
1982
Stereoselective Direct Copper-Catalyzed Alkenylation of Oxazoles with Bromoalkenes
2008
Acetylcholine Receptor: An Allosteric Protein
1984 Science
Iron Catalysis in Organic Synthesis
2015 Standout
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
3d Transition Metals for C–H Activation
2018 Standout
Catalytic Asymmetric Additions of Enol Silanes to In Situ Generated Cyclic, AliphaticN‐Acyliminium Ions
2021 StandoutNobel
A Convenient Synthesis of Simple Tetrahydroisoquinolines
1984
Catalytic Asymmetric Dearomatizing Redox Cross Coupling of Ketones with Aryl Hydrazines Giving 1,4-Diketones
2015 StandoutNobel
The Thionium/N-Acyliminium Ion Cyclization Cascade as a Strategy for the Synthesis of Azapolycyclic Ring Systems
2000
Structure−Activity Relationships of the Antimalarial Agent Artemisinin. 7. Direct Modification of (+)-Artemisinin and In Vivo Antimalarial Screening of New, Potential Preclinical Antimalarial Candidates
2002
Induktion von Asymmetrie durch Aminosäuren
2006
A Chiral Route to Both Enantiomers of Physostigmine and the First Synthesis of (−)-Norphysostigmine
1990
Allocolchicinoid Synthesis via Direct Arylation
2005
Asymmetric Electrophilic α‐Amidoalkylation, VII1): Generation, Crystal Structure, and Trapping Reactions of a Chiral 6,7‐Dimethoxy‐1,2,3,4‐tetrahydroisoquinoline Derived N‐Acyliminium Ion
1990
Asymmetric 13-dipolar cycloaddition of nitrones with ketene acetals catalyzed by chiral oxazaborolidines
1994
Induction of Asymmetry by Amino Acids
1982
Hydroamination: Direct Addition of Amines to Alkenes and Alkynes
2008 Standout
Conformational analysis of some chiral catalysts of the cinchona1 and ephedra2 family. The alkaloid catalyzed addition of aromatic thiols to cyclic α,β‐unsaturated ketones
1989
Enantioselective synthesis of (S)-calycotomine employing catalytic asymmetric hydrogenation with an iridium(I)–(R)-BINAP–phthalimide complex
1998
Organocatalysis by N-Heterocyclic Carbenes
2007 Standout
Pictet-Spengler reaction of biogenic amines with (2R)-N-Glyoxyloylbornane-10,2-sultam. Enantioselective synthesis of (S)-(+)-N-methylcalycotomine
1995
Reactions with indole derivatives-LV.
1987
Divergent Enantioselective Synthesis of (−)-Galanthamine and (−)-Morphine
2005
Charge Carrier Transporting Molecular Materials and Their Applications in Devices
2007 Standout
Palladium(II)-catalyzed formation of γ-butyrolactones from 4-trimethylsilyl-3-alkyn-1-ols: Synthetic and mechanistic aspects
1996
Synthetic Principles for Bandgap Control in Linear π-Conjugated Systems
1997 Standout
Bright Side of Lignin Depolymerization: Toward New Platform Chemicals
2018 Standout
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Catalytic Asymmetric Allylation of 3,4-Dihydroisoquinolines and Its Application to the Synthesis of Isoquinoline Alkaloids
2010
Oxidative phenol coupling with cupric-amine complexes
1977 StandoutNobel
Reaction of antimalarial endoperoxides with specific parasite proteins
1994
Synthesis of unsymmetrical 2,5-di-n-alkylpyrrolidines: 2-hexyl-5-pentylpyrrolidine from the thief ants , and its homologues.
1979
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
2017 StandoutNobel
Probes for a Regulatory Site on the Nicotinic Acetylcholine Receptor‐Channel. Synthesis of (±)‐7‐Debutylperhydrohistrionicotoxin, (±)‐2‐Depentyl‐7‐debutylperhydrohistrionicotoxin, and their Analogues
1985
Oxazoline as a useful tool in organic synthesis: preparation of 4-aryl-1,2,3,4-tetrahydroisoquinoline alkaloid skeleton
2005
Antimalarial Compounds from Rhaphidophora decursiva
2001
Synthesis of 3-(arylmethylene)isoindolin-1-ones from ynamides by Heck–Suzuki–Miyaura domino reactions. Application to the synthesis of lennoxamine
2006
A Novel Synthesis of Substituted 1-Benzyloctahydroisoquinolines by Acid-Catalyzed Cyclization ofN-[2-(Cyclohex-1-enyl)ethyl]-N-styrylformamides
1998
Cyclizations of N-Acyliminium Ions
2004 Standout
Alternative Synthetic Methods through New Developments in Catalysis by Gold
2008 Standout
New Chiral Phosphorus Ligands for Enantioselective Hydrogenation
2003 Standout
Helical Polymers: Synthesis, Structures, and Functions
2009 Standout
Opiate Receptor: Demonstration in Nervous Tissue
1973 StandoutScience
The Cinchona Primary Amine-Catalyzed Asymmetric Epoxidation and Hydroperoxidation of α,β-Unsaturated Carbonyl Compounds with Hydrogen Peroxide
2013 StandoutNobel
A short route to functionalized imidazo[4,5- c ]carbazoles. Synthesis of the first example of the imidazo[4,5- c ]β-carboline ring system
2001
Transition metal complexes in organic synthesis. Part 62: Total synthesis of (±)-demethoxycarbonyldihydrogambirtannine and norketoyobyrine by an iron-mediated [2+2+1] cycloaddition
2000
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation
2016 StandoutNobel
Aromatic Trifluoromethylation with Metal Complexes
2011 Standout
Biochemical and Pharmacological Characterization of [3H]GBR 12935 Binding In Vitro to Rat Striatal Membranes: Labeling of the Dopamine Uptake Complex
1987
Emerging Targets in Photopharmacology
2016 StandoutNobel
Nucleophilic substitution studies on nitroimidazoles, and applications to the synthesis of biologically active compounds
2000
Reaktionen an Indolderivaten, XXV. Die stereoselektive Totalsynthese des Roxburghins D
1975
Oxidative Stress, Glutamate, and Neurodegenerative Disorders
1993 StandoutScience
Transition-Metal-Catalyzed Addition of Heteroatom−Hydrogen Bonds to Alkynes
2004 Standout
Stereochemical Factors and Receptor Interactions Associated with Narcotic Analgesics
1966
Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics
1999 StandoutScience
The Catalytic Asymmetric Fischer Indolization
2011 StandoutNobel
Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation
2009 Standout
Metalation vs Nucleophilic Addition in the Reactions of N-Phenethylimides with Organolithium Reagents. Ready Access to Isoquinoline Derivatives via N-Acyliminium Ions and Parham-Type Cyclizations
1997
Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide
2011 StandoutScience
Enantioselective Synthesis of Some Tetracyclic Isoquinoline Alkaloids by Asymmetric Transfer Hydrogenation Catalysed by a Chiral Ruthenium Complex
2005
Synthesis and Characterization of Nitroaromatic Peptoids: Fine Tuning Peptoid Secondary Structure through Monomer Position and Functionality
2009
Isolation and Synthesis of Biologically Active Carbazole Alkaloids
2002 Standout
Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction
2002 Standout
Cyclohexadienone Ketals and Quinols: Four Building Blocks Potentially Useful for Enantioselective Synthesis
2004
Saframycin synthetic studies
1991
Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine
1987 StandoutScience
A total synthesis of griseofulvin and its optical antipode
1963
Catalytic Asymmetric Pictet−Spengler Reaction
2006 StandoutNobel
Works of A. BROSSI being referenced
Comparative inhibitory effects of various physostigmine analogs against acetyl- and butyrylcholinesterases.
1989
Interaction of analogs of histrionicotoxin with the acetylcholine receptor ionic channel complex and membrane excitability.
1984
The ionic channel of the nicotinic acetylcholine receptor is unable to differentiate between the optical antipodes of perhydrohistrionicotoxin
1983
Enantiomer (+)physostigmine prevents organophosphate‐induced subjunctional damage at the neuromuscular synapse by a mechanism not related to cholinesterase carbamylation
1988
Neurotoxic damage to the nigrostriatal system in rats following intranigral administration of MPDP+ and MPP+
1988
Arteether, a new antimalarial drug: synthesis and antimalarial properties
1988
Syntheseversuche in der Emetin‐Reihe. 1. Mitteilung. 2‐Oxo‐hydrobenzo[a]chinolizine
1958
Total synthesis of racemic cherylline
1970
Syntheseversuche in der Griseofulvinreihe. 3. Mitteilung. Eine neue Ringöffnung bei Dehydrogriseofulvin
1962
Darstellung und Eigenschaften verschiedener 3‐Benzazocine, eine Klasse potentieller Analgetika
1970
N-acetylcolchinol O-methyl ether and thiocolchicine, potent analogs of colchicine modified in the C ring. Evaluation of the mechanistic basis for their enhanced biological properties.
1990
A New Synthesis of "Schöpf's Base VI" and Related 10H-Isoindolo[2,3-c] benzazepines
1972
Presence and formation of codeine and morphine in the rat.
1986
The Nuclear Magnetic Resonance Spectra of the Angular Proton in Benzo[a]- and Indolo[a]quinolizidines
1964
Homoberbine, eine neue Klasse heterocyclischer Verbindungen
1969
Syntheseversuche in der Emetinreihe. 9. Mitteilung. Die absolute Konfiguration von (−)‐2‐Dehydro‐emetin
1962
Synthesen in der Isochinolinreihe Halogensubstituierte 1‐(ω‐Phenylalkyl)‐1,2,3,4‐tetrahydro‐isochinoline als Analgetica
1960
Syntheseversuche in der Griseofulvin‐Reihe. Vorläufige Mitteilung. Totalsynthese von Griseofulvin
1960
Absolute Configuration of Deglucopterocereine: Conversion into R-(+)-N-Methylcalycotomine
1985
Synthesen in der Isochinolinreihe Zur Konfiguration von (−)‐1‐(p‐Chlorphenäthyl)‐2‐methyl‐6,7‐dimethoxy‐1,2,3,4‐tetrahydro‐isochinolin
1961
Syntheseversuche in der Griseofulvinreihe. 1. Mitteilung. Eine Totalsynthese von Griseofulvin
1960
Nitroimidazoles II. synthesis and reactions of iodonitroimidazoles
1966
‘Alkaloids’ in Mammalian Tissues. I. Condensation of L ‐Dopa and its two mono‐O‐methyl ethers with formaldehyde and acetaldehyde
1972
Pavinan and isopavinan alkaloids. Synthesis of racemic and natural thalidine, bisnorargemonine, and congeners from N-norreticuline
1980
B ring regulation of colchicine binding kinetics and fluorescence.
1986
Preparation ofR(+)- andS(-)-α-Methyl-p-nitrobenzylamines and Their Use as Resolving Agents
1977
Serotonergic conversion of MPTP and dopaminergic accumulation of MPP+
1985
Natural products. Antitubulin effect of congeners of N-acetylcolchinyl methyl ether: synthesis of optically active 5-acetamidodeaminocolchinyl methyl ether and of demethoxy analogues of deaminocolchinyl methyl ether
1992
Synthesen in der Isochinolinreihe Neue Synthesen der Kaktusalkaloide Anhalamin, Anhalidin, rac. Anhalonidin und rac. Pellotin
1964
Synthesis in the Emetine Series XV1) Friedel-Crafts Acylation of N-Acetylhomoveratrylamine: A Facile Synthesis of 9,10-Dimethoxybenzo[a]Quinolizidine
1972
Syntheses of various 2,5‐disubstituted oxazole derivatives related to natural products
1965
Synthesen in der Isochinolinreihe Synthesen von 7‐Hydroxy ‐6‐methoxy‐2‐methyl‐ 1‐(4‐hydroxy‐3, 5‐dimethoxy‐phenäthyl)‐1, 2, 3, 4‐tetrahydro‐isochinolin, einem wichtigen Zwischenprodukt zur Synthese von Homoapomorphin‐Alkaloiden
1968
Some recent results on the chemotherapy of amebiasis, coccidiosis, and malaria
1969
Syntheseversuche in der Emetin‐Reihe. 5. Mitteilung. Eine neue Totalsynthese von Emetin
1959
Konfiguration und pharmakologische Aktivität bei 1-phenäthylsubstituierten 1,2,3,4-Tetrahydroisochinolinen
1964
Colchicine binding to antibodies.
1980