Citation Impact
Citing Papers
Sensitization of Human Carcinoma Cells to Alkylating Agents by Small Interfering RNA Suppression of 3-Alkyladenine-DNA Glycosylase
2005 StandoutNobel
Selectivity and proofreading both contribute significantly to the fidelity of RNA polymerase III transcription
2007
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease
2010 StandoutScienceNobel
RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription
2010 StandoutNobel
Loss of the Mismatch Repair Protein MSH6 in Human Glioblastomas Is Associated with Tumor Progression during Temozolomide Treatment
2007
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.
1999
Hallmarks of Cancer: The Next Generation
2011 Standout
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
2000 StandoutNature
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Structural Basis of Transcription
2004 StandoutNobel
The role of DNA damage and repair in aging through the prism of Koch-like criteria
2012
Overproduction in Escherichia coli and Characterization of Yeast Replication Factor C Lacking the Ligase Homology Domain
2000
Nucleic acid polymerases use a general acid for nucleotidyl transfer
2009
MGMT: Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents
2007
Inflammation and metabolic disorders
2006 StandoutNature
Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity
2001
Exonuclease X of Escherichia coli
1999
NMDA receptor activation in rat hippocampus induces cyclic GMP formation through the l-arginine-nitric oxide pathway
1991
APE1/Ref-1Role in Redox Signaling: Translational Applications of Targeting the Redox Function of the DNA Repair/Redox Protein APE1/Ref-1
2011
Prokaryotic DNA polymerase I: evolution, structure, and “base flipping” mechanism for nucleotide selection
2001
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Whole Genome Sequences of a Male and Female Supercentenarian, Ages Greater than 114 Years
2012
Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA
2000
A novel neuronal messenger molecule in brain: The free radical, nitric oxide
1992
Transcription elongation factor S‐II maintains transcriptional fidelity and confers oxidative stress resistance
2003
Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase
2006
Inactivation of the DNA-Repair GeneMGMTand the Clinical Response of Gliomas to Alkylating Agents
2000 Standout
Regulatory Roles of p21 and Apurinic/Apyrimidinic Endonuclease 1 in Base Excision Repair
2001
Mechanisms of Helicases
2006
The roles of the eukaryotic DNA polymerases in DNA repair synthesis
1997
Building a Replisome from Interacting Pieces
1999 StandoutNobel
The Exonucleolytic and Endonucleolytic Cleavage Activities of Human Exonuclease 1 Are Stimulated by an Interaction with the Carboxyl-terminal Region of the Werner Syndrome Protein
2003
MGMT: its role in cancer aetiology and cancer therapeutics
2004
Site-directed mutagenesis of the YCDTDS amino acid motif of the Φ29 DNA polymerase
1990
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
RecQ helicase, in concert with RecA and SSB proteins, initiates and disrupts DNA recombination
1998
Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)
1997
RecQ Helicase and Topoisomerase III Comprise a Novel DNA Strand Passage Function
1999
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
Delayed repletion of O6-methylguanine—DNA methyltransferase resulting in failure to protect the human glioblastoma cell line SF767 from temozolomide-induced cytotoxicity
2003
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Nitric Oxide Acts Directly in the Presynaptic Neuron to Produce Long-Term Potentiationin Cultured Hippocampal Neurons
1996 StandoutNobel
Extrachromosomal rDNA Circles— A Cause of Aging in Yeast
1997
High fidelity TNA synthesis by Therminator polymerase
2005
Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma
2005 Standout
Accuracy of wheat‐germ RNA polymerase II
1992
Insulin resistance and atherosclerosis
2006
A phylogenomic study of DNA repair genes, proteins, and processes
1999
Molecular mechanisms of yeast aging
1998
The Hallmarks of Aging
2013 Standout
A sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel
1989
The Structural Mechanism of Translocation and Helicase Activity in T7 RNA Polymerase
2004 StandoutNobel
Repair of O6-alkylguanine by alkyltransferases
2000
Use of an in Vivo Reporter Assay to Test for Transcriptional and Translational Fidelity in Yeast
2002
Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation
1994 StandoutNatureNobel
Telomeres, replicative senescence and human ageing
2001
MGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma
2005 Standout
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Nitric Oxide And Carbon Monoxide Produce Activity-Dependent Long-Term Synaptic Enhancement in Hippocampus
1993 StandoutScienceNobel
The Free Radical Theory of Aging Matures
1998 Standout
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Properties of the exonuclease activity that degrades H4 histone mRNA.
1987
Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger.
1991 StandoutNobel
Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells
1985
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
The p38 Mitogen-Activated Protein Kinase Pathway Links the DNA Mismatch Repair System to the G2 Checkpoint and to Resistance to Chemotherapeutic DNA-Methylating Agents
2003
In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair
2001 StandoutNobel
Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.
1996 StandoutNobel
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
WRN Helicase and FEN-1 Form a Complex upon Replication Arrest and Together Process Branchmigrating DNA Structures Associated with the Replication Fork
2003
Repair and Genetic Consequences of Endogenous DNA Base Damage in Mammalian Cells
2004 StandoutNobel
Controlling mRNA lifespan
1988 StandoutNatureNobel
Ribonuclease A
1998
Promoter Hypermethylation of the DNA Repair Gene O6‐Methylguanine‐DNA Methyltransferase is an Independent Predictor of Shortened Progression Free Survival in Patients with Low‐grade Diffuse Astrocytomas
2003
Werner syndrome protein interacts functionally with translesion DNA polymerases
2007
Aging, life span, and senescence
1998 StandoutNobel
Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen
1989 StandoutScience
Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia
1998 StandoutNobel
Endothelial NOS and the Blockade of LTP by NOS Inhibitors in Mice Lacking Neuronal NOS
1994 StandoutScienceNobel
Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template
2007 StandoutNobel
A mutant T7 RNA polymerase as a DNA polymerase.
1995
RNA polymerase II subunit Rpb9 is important for transcriptional fidelity in vivo
2006
Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase
1997 StandoutNobel
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
Oxidative Stress, Glutamate, and Neurodegenerative Disorders
1993 StandoutScience
Human DNA Repair Genes
2001 StandoutScienceNobel
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Noncytopathic Sindbis virus RNA vectors for heterologous gene expression
1998 StandoutNobel
Immunohistochemical localization of guanylate cyclase within neurons of rat brain.
1982 StandoutNobel
Methylation of Discrete Regions of the O6-Methylguanine DNA Methyltransferase (MGMT) CpG Island Is Associated with Heterochromatinization of the MGMT Transcription Start Site and Silencing of the Gene
1997
Works of A. Blank being referenced
The Werner syndrome protein is a DNA helicase
1997
The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function
2004
Thermus aquaticus DNA Polymerase I Mutants with Altered Fidelity
2000
Contribution of O6‐methylguanine‐DNA methyltransferase to monofunctional alkylating‐agent resistance in human brain tumor—derived cell lines
1995
Relationships between seizure activity and cyclic nucleotide levels in brain
1980
An RNA polymerase mutant with reduced accuracy of chain elongation
1986
Activity staining of nucleolytic enzymes after sodium dodecyl sulfate-polyacrylamide gel electrophoresis: Use of aqueous isopropanol to remove detergent from gels
1982
Ribonucleases of human serum, urine, cerebrospinal fluid, and leukocytes. Activity staining following electrophoresis in sodium dodecyl sulfate-polyacrylamide gels
1981
O6-methylguanine-DNA methyltransferase activity in adult gliomas: relation to patient and tumor characteristics.
1998
DNA polymerase delta is required for base excision repair of DNA methylation damage in Saccharomyces cerevisiae.
1994
Apurinic/apyrimidinic endonuclease activity is elevated in human adult gliomas.
2001
Detection of enzymatic activities in sodium dodecyl sulfate-polyacrylamide gels: DNA polymerases as model enzymes
1983
O6-methylguanine-DNA methyltransferase-deficient phenotype in human gliomas: frequency and time to tumor progression after alkylating agent-based chemotherapy.
1999
Role of O6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin.
1996
The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress.
2002
Lack of the DNA repair protein O6-methylguanine-DNA methyltransferase in histologically normal brain adjacent to primary human brain tumors.
1996