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Citing Papers
Rapid protein fold determination using unassigned NMR data
2003 StandoutNobel
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
2005 StandoutNobel
Evolution of new nonantibody proteins via iterative somatic hypermutation
2004 StandoutNobel
RNA-Guided Human Genome Engineering via Cas9
2013 StandoutScience
Merlin/ NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane
2005
Cell type-specific roles for Cdc42, Rac, and RhoL in Drosophila oogenesis.
1996
Murine leukemia provirus‐mediated activation of the Notch1 gene leads to induction of HES‐1 in a mouse T lymphoma cell line, DL‐3
1999 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
CD44 is required for two consecutive steps in HGF/c-Met signaling
2002
Temporally controlled targeted somatic mutagenesis in skeletal muscles of the mouse
2005
Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger
1999 StandoutNobel
Activation of Phosphoinositide 3-OH Kinase by the α6β4 Integrin Promotes Carcinoma Invasion
1997
Leukaemia disease genes: large-scale cloning and pathway predictions
1999
Improved molecular replacement by density- and energy-guided protein structure optimization
2011 StandoutNatureNobel
CD44: From adhesion molecules to signalling regulators
2003 Standout
ICOS co-stimulatory receptor is essential for T-cell activation and function
2001 StandoutNatureNobel
A transcription activator-like effector toolbox for genome engineering
2012
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors
1998
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Synergistic Roles for Pim-1 and c-Myc in STAT3-Mediated Cell Cycle Progression and Antiapoptosis
1999
Functional Analysis of the Neurofibromatosis Type 2 Protein by Means of Disease-Causing Point Mutations
2000
Signal transduction and actin filament organization
1996
Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis
2010
ERM proteins and merlin: integrators at the cell cortex
2002 Standout
Positive and Negative Regulation of Nuclear Factor-κB-mediated Transcription by IκB-ζ, an Inducible Nuclear Protein
2004
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
Site- and Time-Specific Gene Targeting in the Mouse
2001
BCL-3 and NF-κB p50 Attenuate Lipopolysaccharide-induced Inflammatory Responses in Macrophages
2004
The level of CD8 expression can determine the outcome of thymic selection
1992 StandoutNobel
Cancer Modeling in the Modern Era
2002
Impaired Bcl3 Up-regulation Leads to Enhanced Lipopolysaccharide-induced Interleukin (IL)-23P19 Gene Expression in IL-10–/– Mice
2008
Identification of a Mouse p21Cdc42/Rac Activated Kinase
1995
Ezrin, radixin, and moesin are components of Schwann cell microvilli
2001
Lfc and Lsc Oncoproteins Represent Two New Guanine Nucleotide Exchange Factors for the Rho GTP-binding Protein
1996
The Dbl family of oncogenes
1996
MAIL, a novel nuclear IκB protein that potentiates LPS‐induced IL‐6 production
2000
Gene Switching and the Stability of Odorant Receptor Gene Choice
2004 StandoutNobel
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
ERM proteins and NF2 tumor suppressor: the Yin and Yang of cortical actin organization and cell growth signaling
2002
T Cell Selection in the Thymus
1988
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
1997
A role for Rac in Tiaml-induced membrane ruffling and invasion
1995 Nature
Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse
2002
Rho GTPases and signaling networks
1997 Standout
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44
2001
The Nf2 Tumor Suppressor, Merlin, Functions in Rac-Dependent Signaling
2001
Abnormal organogenesis of Peyer's patches in mice deficient for NF-κB1, NF-κB2, and Bcl-3
2002
Immunological adjuvants promote activated T cell survival via induction of Bcl-3
2001
Comparative biology of mouse versus human cells: modelling human cancer in mice
2003
NF-kappa B p105 is a target of Ikappa B kinases and controls signal induction of Bcl-3-p50 complexes
1999
The Rac and Rho pathways as a source of drug targets for Ras-mediated malignancies
1995
CD44 Interaction with Tiam1 Promotes Rac1 Signaling and Hyaluronic Acid-mediated Breast Tumor Cell Migration
2000
Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage
1991 StandoutNobel
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
2001 Standout
A Fresh Look at iPS Cells
2009 StandoutNobel
Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac
2000
Rhotekin, a New Putative Target for Rho Bearing Homology to a Serine/Threonine Kinase, PKN, and Rhophilin in the Rho-binding Domain
1996
Crystal Structure of Human RhoA in a Dominantly Active Form Complexed with a GTP Analogue
1998
Neuronal polarity: from extracellular signals to intracellular mechanisms
2007
Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination
2003 Standout
The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange
1998 StandoutNatureNobel
Signaling to NF-κB
2004 Standout
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
PH domain: the first anniversary
1994
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
2009 Standout
Direct Involvement of the Small GTP-binding Protein Rho in lbc Oncogene Function
1995
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Mice cloned from olfactory sensory neurons
2004 StandoutNatureNobel
Merlin Phosphorylation by p21-activated Kinase 2 and Effects of Phosphorylation on Merlin Localization
2002
Extrathymic positive selection of αβ T-cell precursors in nude mice
1992 StandoutNatureNobel
Unravelling the complexities of the NF-κB signalling pathway using mouse knockout and transgenic models
2006
Role of Tiam 1 in Rac-Mediated Signal Transduction Pathways
1996
Mice Deficient in Nuclear Factor (NF)-κB/p52 Present with Defects in Humoral Responses, Germinal Center Reactions, and Splenic Microarchitecture
1998
Synaptic development is controlled in the periactive zones of Drosophila synapses
2000
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Small GTP-Binding Proteins
2001 Standout
Bcl-3 Expression Promotes Cell Survival following Interleukin-4 Deprivation and Is Controlled by AP1 and AP1-Like Transcription Factors
2000
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice
2007 StandoutNobel
NF-κB RegulatesBCL3Transcription in T Lymphocytes Through an Intronic Enhancer
2003
Expression of CD4 in transgenic mice alters the specificity of CD8 cells for allogeneic major histocompatibility complex.
1991 StandoutNobel
Cytoplasmic Sequestration of Rel Proteins by IκBα Requires CRM1-Dependent Nuclear Export
2000
Expression in transgenic mice of class I histocompatibility antigens controlled by the metallothionein promoter.
1989 StandoutNobel
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
Regulation and Function of NF-κB Transcription Factors in the Immune System
2009 Standout
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Rac Downregulates Rho Activity
1999
Identification of Notch1 as a Frequent Target for Provirus Insertional Mutagenesis in T-Cell Lymphomas Induced by Leukemogenic Mutants of Mouse Mammary Tumor Virus
2000 StandoutNobel
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
The outline structure of the T-cell alpha beta receptor.
1988
Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains
1997 Science
Cytokinesis arrest and redistribution of actin-cytoskeleton regulatory components in cells expressing the Rho GTPase CDC42Hs
1996
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids
2000 StandoutNobel
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Contact-dependent inhibition of EGFR signaling by Nf2/Merlin
2007
Functional Redundancy of the Nuclear Factor κB Inhibitors IκBα and IκBβ
1998
Characterization of rho GTPase family homologues in Drosophila melanogaster: overexpressing Rho1 in retinal cells causes a late developmental defect.
1995
NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses
1998 Standout
Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback
2005
PD-1 deficiency reveals various tissue-specific autoimmunity by H-2band dose-dependent requirement of H-2g7for diabetes in NOD mice
2008 StandoutNobel
Cutting Edge: Bcl-3 Up-Regulation by Signal 3 Cytokine (IL-12) Prolongs Survival of Antigen-Activated CD8 T Cells
2005
Regulated Membrane Localization of Tiam1, Mediated by the NH2-terminal Pleckstrin Homology Domain, Is Required for Rac-dependent Membrane Ruffling and C-Jun NH2-terminal Kinase Activation
1997
Expression of Interleukin 9 in the Lungs of Transgenic Mice Causes Airway Inflammation, Mast Cell Hyperplasia, and Bronchial Hyperresponsiveness
1998
Fission yeast orb 6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle
1998 StandoutNobel
Inhibition of Invasion of Epithelial Cells by Tiam1-Rac Signaling
1997 Science
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-α production in macrophages
2003
The Guanine Nucleotide Exchange Factor Tiam1 Affects Neuronal Morphology; Opposing Roles for the Small GTPases Rac and Rho
1997
Identification of a novel Rac1-interacting protein involved in membrane ruffling.
1996
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.
1996
Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b −/− Pdcd1 −/− mice
2005 StandoutNobel
ERM-Merlin and EBP50 Protein Families in Plasma Membrane Organization and Function
2000
A C-terminal motif found in the β 2 -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na + /H + exchanger regulatory factor family of PDZ proteins
1998 StandoutNobel
Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon cre-mediated excision
2000
T cell selection in the thymus.
1988
Negative Regulation of Toll-Like Receptor Signaling by NF-κB p50 Ubiquitination Blockade
2007 Science
Nuclear Factor (NF)-κB2 (p100/p52) Is Required for Normal Splenic Microarchitecture and B Cell–mediated Immune Responses
1998
Works of A. Berns being referenced
Thymic lymphomas in interleukin 9 transgenic mice.
1994
Cre-mediated somatic site-specific recombination in mice
1997
Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins
1994
Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc
1997
Schwann cell hyperplasia and tumors in transgenic mice expressing a naturally occurring mutant NF2 protein
1999
Complementation tagging of cooperating oncogenes in knockout mice
1996
Retroviral insertional mutagenesis as a strategy to identify cancer genes
1996
HLA-restricted recognition of viral antigens in HLA transgenic mice
1987 Nature
Immunological defects in mice with a targeted disruption in Bcl-3.
1997
Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2
2000
Pim-1 levels determine the size of early B lymphoid compartments in bone marrow.
1993