Standout Papers
Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
RNA tertiary interactions in the large ribosomal subunit: The A-minor motif
2001 StandoutNobel
The ribosome as an entropy trap
2004
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Recognition of Cognate Transfer RNA by the 30 S Ribosomal Subunit
2001 StandoutScienceNobel
Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity
2007 StandoutNobel
Structure of the 70 S Ribosome Complexed with mRNA and tRNA
2006 StandoutScienceNobel
Structures of the Bacterial Ribosome at 3.5 A Resolution
2005 Science
Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes
2008
The Ribosome as a Conveying Thermal Ratchet Machine
2009
Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin
2004 StandoutNobel
Structure of the signal recognition particle interacting with the elongation-arrested ribosome
2004 StandoutNatureNobel
The kink-turn: a new RNA secondary structure motif
2001
Short peptides conferring resistance to macrolide antibiotics
2001
tRNA selection and kinetic proofreading in translation
2004 Nobel
3.3 Å Cryo-EM Structure of a Nonenveloped Virus Reveals a Priming Mechanism for Cell Entry
2010
Crystal structure of ribosomal protein L27 from Thermus thermophilus HB8
2004
Interaction of Translation Initiation Factor 3 with the 30S Ribosomal Subunit
2001
The G2447A mutation does not affect ionization of a ribosomal group taking part in peptide bond formation
2003
Ratchet-like Movements between the Two Ribosomal Subunits: Their Implications in Elongation Factor Recognition and tRNA Translocation
2001 StandoutNobel
Mapping Functionally Important Motifs SPF and GGQ of the Decoding Release Factor RF2 to the Escherichia coli Ribosome by Hydroxyl Radical Footprinting
2003
Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3
2001
Translation initiation factor IF3: two domains, five functions, one mechanism?
2001
The transorientation hypothesis for codon recognition during protein synthesis
2002 Nature
Long-Residency Hydration, Cation Binding, and Dynamics of Loop E/Helix IV rRNA-L25 Protein Complex
2004
Beyond kinetic traps in RNA folding
2001
The Structures of Four Macrolide Antibiotics Bound to the Large Ribosomal Subunit
2002 StandoutNobel
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Chemical engineering of the peptidyl transferase center reveals an important role of the 2'-hydroxyl group of A2451
2005
Essential Mechanisms in the Catalysis of Peptide Bond Formation on the Ribosome
2005
The Ribosomal Peptidyl Transferase
2007
Locking and Unlocking of Ribosomal Motions
2003 StandoutNobel
Global ribosome motions revealed with elastic network model
2004
Important Contribution to Catalysis of Peptide Bond Formation by a Single Ionizing Group within the Ribosome
2002
A universal mode of helix packing in RNA.
2001 StandoutNobel
Structural insight into the role of the ribosomal tunnel in cellular regulation
2003 StandoutNobel
Ribosome as a molecular machine
2002
Orientation of Ribosome Recycling Factor in the Ribosome from Directed Hydroxyl Radical Probing
2002
Non-Watson-Crick Basepairing and Hydration in RNA Motifs: Molecular Dynamics of 5S rRNA Loop E
2003
Coupling of Ribosomal L1 Stalk and tRNA Dynamics during Translation Elongation
2008
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
Localization of the Trigger Factor Binding Site on the Ribosomal 50S Subunit
2003
Peptide bond formation on the ribosome: structure and mechanism
2003
All-atom homology model of the Escherichia coli 30S ribosomal subunit
2002
A hierarchical model for evolution of 23S ribosomal RNA
2009 Nature
A fast dynamic mode of the EF‐G‐bound ribosome
2009
The Structural Basis of Macrolide–Ribosome Binding Assessed Using Mutagenesis of 23S rRNA Positions 2058 and 2059
2004
A cryo-electron microscopic study of ribosome-bound termination factor RF2
2003 StandoutNatureNobel
Peptide bond formation does not involve acid-base catalysis by ribosomal residues
2006
Nonbridging phosphate oxygens in 16S rRNA important for 30S subunit assembly and association with the 50S ribosomal subunit
2005
Hinge-Like Motions in RNA Kink-Turns: The Role of the Second A-Minor Motif and Nominally Unpaired Bases
2005
On peptide bond formation, translocation, nascent protein progression and the regulatory properties of ribosomes
2003 StandoutNobel
Atomic structures at last: the ribosome in 2000
2001 StandoutNobel
Reproducible growth of well diffracting ribosomal crystals
2005 StandoutNobel
Distribution of rRNA Introns in the Three-dimensional Structure of the Ribosome
2002
Site-specific labeling of the ribosome for single-molecule spectroscopy
2005
From peptide‐bond formation to cotranslational folding: dynamic, regulatory and evolutionary aspects
2004 StandoutNobel
Correlating ribosome function with high-resolution structures
2008 StandoutNobel
Macrolide Antibiotics: Binding Site, Mechanism of Action, Resistance
2003
Ribosomal crystallography: Peptide bond formation and its inhibition
2003 StandoutNobel
Structural dynamics of the ribosome
2008
Structure of the E. coli protein-conducting channel bound to a translating ribosome
2005 StandoutNatureNobel
Ribosome interactions of aminoacyl-tRNA and elongation factor Tu in the codon-recognition complex
2002
Transit of tRNA through the Escherichia coli ribosome: cross‐linking of the 3′ end of tRNA to ribosomal proteins at the P and E sites
2002
Localization of L11 protein on the ribosome and elucidation of its involvement in EF-G-dependent translocation
2001 StandoutNobel
The signal recognition particle binds to protein L23 at the peptide exit of the Escherichia coli ribosome
2003
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
RNA Kink-Turns as Molecular Elbows: Hydration, Cation Binding, and Large-Scale Dynamics
2006
Localization of the Ribosomal Protection Protein Tet(O) on the Ribosome and the Mechanism of Tetracycline Resistance
2001
Structure of the Mammalian Ribosome–Channel Complex at 17Å Resolution
2002
Structural Basis for the Antibiotic Activity of Ketolides and Azalides
2003 StandoutNobel
The Structural Basis for the Action of the Antibiotics Tetracycline, Pactamycin, and Hygromycin B on the 30S Ribosomal Subunit
2000 StandoutNobel
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
The kink-turn motif in RNA is dimorphic, and metal ion-dependent
2004
Ribosomal crystallography: a flexible nucleotide anchoring tRNA translocation, facilitates peptide‐bond formation, chirality discrimination and antibiotics synergism
2004 StandoutNobel
X‐ray crystallography study on ribosome recycling: the mechanism of binding and action of RRF on the 50S ribosomal subunit
2004
High-resolution Structures of Ribosomal Subunits: Initiation, Inhibition, and Conformational Variability
2001 StandoutNobel
Structural and functional analysis of 5S rRNA in Saccharomyces cerevisiae
2005
Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements
2006
Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM
2009 StandoutNobel
Structural Basis for the Function of the Ribosomal L7/12 Stalk in Factor Binding and GTPase Activation
2005
Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
2003 StandoutNobel
A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503
2005
Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: purification, crystallization and structure determination
2001 StandoutNobel
The crystal structure of a 26-nucleotide RNA containing a hook-turn
2003
GTP Hydrolysis by IF2 Guides Progression of the Ribosome into Elongation
2009
Cryo-EM Visualization of a Viral Internal Ribosome Entry Site Bound to Human Ribosomes
2004 StandoutNobel
L22 Ribosomal Protein and Effect of Its Mutation on Ribosome Resistance to Erythromycin
2002
Translational Regulation via L11: Molecular Switches on the Ribosome Turned On and Off by Thiostrepton and Micrococcin
2008
The Eukaryotic Translation Initiation Factors eIF1 and eIF1A Induce an Open Conformation of the 40S Ribosome
2007 StandoutNobel
A Protein Component at the Heart of an RNA Machine: The Importance of Protein L27 for the Function of the Bacterial Ribosome
2005
Ribosome fidelity: tRNA discrimination, proofreading and induced fit
2001
Spontaneous reverse movement of mRNA-bound tRNA through the ribosome
2007
Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
2002 StandoutNobel
Symmetry at the active site of the ribosome: structural and functional implications
2005 StandoutNobel
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
2005 StandoutNatureNobel
Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon
2005 StandoutNobel
Ribosomal Tolerance and Peptide Bond Formation
2003 StandoutNobel
Structural dynamics of ribosomal RNA during decoding on the ribosome
2002
Genetic evidence against the 16S ribosomal RNA helix 27 conformational switch model
2003
Crosslinking of 4.5S RNA to the Escherichia coli ribosome in the presence or absence of the protein Ffh
2002
Crystal structure of the 30 s ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 s RNA
2002 StandoutNobel
The role of tRNA as a molecular spring in decoding, accommodation, and peptidyl transfer
2004 StandoutNobel
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Ribosomal antibiotics: structural basis for resistance, synergism and selectivity
2004 StandoutNobel
The Role of 23S Ribosomal RNA Residue A2451 in Peptide Bond Synthesis Revealed by Atomic Mutagenesis
2008
Structural Basis of the Ribosomal Machinery for Peptide Bond Formation, Translocation, and Nascent Chain Progression
2003 StandoutNobel
An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA
2005 StandoutNatureNobel
Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation
2004 StandoutNobel
Structural basis for messenger RNA movement on the ribosome
2006 Nature
Multiple stages in codon–anticodon recognition:double-trigger mechanisms and geometric constraints☆
2006
Progress Toward an Understanding of the Structure and Enzymatic Mechanism of the Large Ribosomal Subunit
2001 StandoutNobel
RNAmmer: consistent and rapid annotation of ribosomal RNA genes
2007 Standout
Ribosome Structure and the Mechanism of Translation
2002 StandoutNobel
Interactions of Translation Factor EF-G with the Bacterial Ribosome Before and After mRNA Translocation
2004
Study of the Structural Dynamics of the E. coli 70S Ribosome Using Real-Space Refinement
2003 StandoutNobel
Conformations of Flanking Bases in HIV-1 RNA DIS Kissing Complexes Studied by Molecular Dynamics
2007
Structure of the L1 protuberance in the ribosome
2003
The Roles of Ribosomal Proteins in the Structure Assembly, and Evolution of the Large Ribosomal Subunit
2004 StandoutNobel
Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit
2003 StandoutNobel
Structure of the 30S translation initiation complex
2008 Nature
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
2001 StandoutNatureNobel
Number, position, and significance of the pseudouridines in the large subunit ribosomal RNA of Haloarcula marismortui and Deinococcus radiodurans
2005
Conserved Loop Sequence of Helix 69 in Escherichia coli 23 S rRNA Is Involved in A-site tRNA Binding and Translational Fidelity
2006
Structure of the 80S Ribosome from Saccharomyces cerevisiae—tRNA-Ribosome and Subunit-Subunit Interactions
2001 StandoutNobel
The Path of Messenger RNA through the Ribosome
2001
Rapid Kinetic Analysis of EF-G-dependent mRNA Translocation in the Ribosome
2003
Maintenance of the correct open reading frame by the ribosome
2003
Structure and Dynamics of a Processive Brownian Motor: The Translating Ribosome
2010 StandoutNobel
Crystal Structure of the Ribosome at 5.5 Å Resolution
2001 StandoutScience
Resistance to the Peptidyl Transferase Inhibitor Tiamulin Caused by Mutation of Ribosomal Protein L3
2003
Ribosome structure: revisiting the connection between translational accuracy and unconventional decoding
2002
Comprehensive genetic selection revealed essential bases in the peptidyl-transferase center
2006 StandoutNobel
23S rRNA base pair 2057–2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G
2005 StandoutNobel
Mutations in ribosomal protein L3 and 23S ribosomal RNA at the peptidyl transferase centre are associated with reduced susceptibility to tiamulin in Brachyspira spp. isolates
2004
Visualization of protein S1 within the 30S ribosomal subunit and its interaction with messenger RNA
2001 StandoutNobel
Biochemical characterization of the kink-turn RNA motif
2003
Spontaneous formation of the unlocked state of the ribosome is a multistep process
2009
The Structural Basis of Large Ribosomal Subunit Function
2003 StandoutNobel
Chemical parameters influencing fine-tuning in the binding of macrolide antibiotics to the ribosomal tunnel
2007 StandoutNobel
The Search and Its Outcome: High-Resolution Structures of Ribosomal Particles from Mesophilic, Thermophilic, and Halophilic Bacteria at Various Functional States
2002 StandoutNobel
Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin
2004 StandoutNobel
Heptameric (L12)6/L10 rather than canonical pentameric complexes are found by tandem MS of intact ribosomes from thermophilic bacteria
2005
Ribosomal Translocation: One Step Closer to the Molecular Mechanism
2009
Resistance to the macrolide antibiotic tylosin is conferred by single methylations at 23S rRNA nucleotides G748 and A2058 acting in synergy
2002
Ketolide Antimicrobial Activity Persists after Disruption of Interactions with Domain II of 23S rRNA
2004
Intersubunit movement is required for ribosomal translocation
2007
Mechanism of peptide bond synthesis on the ribosome
2005
Deleterious mutations in small subunit ribosomal RNA identify functional sites and potential targets for antibiotics
2005
Polypeptide release at sense and noncognate stop codons by localized charge-exchange alterations in translational release factors
2002
Electrostatics of nanosystems: Application to microtubules and the ribosome
2001 Standout
Translational Operator of mRNA on the Ribosome: How Repressor Proteins Exclude Ribosome Binding
2005 Science
Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications
2004 StandoutNobel
Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy
2003 StandoutNobel
Single-Particle Imaging of Macromolecules by Cryo-Electron Microscopy
2002 StandoutNobel
Irreversible chemical steps control intersubunit dynamics during translation
2008
Structural basis for cross-resistance to ribosomal PTC antibiotics
2008 StandoutNobel
Functional aspects of ribosomal architecture: symmetry, chirality and regulation
2004 StandoutNobel
RIBOSOME DYNAMICS: Insights from Atomic Structure Modeling into Cryo-Electron Microscopy Maps
2006 StandoutNobel
Hepatitis C Virus IRES RNA-Induced Changes in the Conformation of the 40 S Ribosomal Subunit
2001 StandoutScienceNobel
Following movement of the L1 stalk between three functional states in single ribosomes
2009
X-ray crystal structures of the WT and a hyper-accurate ribosome from Escherichia coli
2003
Role of Ribosomal Protein L27 in Peptidyl Transfer
2008
ANTIBIOTICS TARGETING RIBOSOMES: Resistance, Selectivity, Synergism, and Cellular Regulation
2005 StandoutNobel
The process of mRNA–tRNA translocation
2007 StandoutNobel
RNA Structure: Reading the Ribosome
2005 Science
Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on theEscherichia coliribosome
2003
Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
2008 StandoutNobel
Mutational Analysis of 16S and 23S rRNA Genes of Thermus thermophilus
2005
tRNA dynamics on the ribosome during translation
2004 Nobel
Structure of trigger factor binding domain in biologically homologous complex with eubacterial ribosome reveals its chaperone action
2005 StandoutNobel
Ribosomal Crystallography: Initiation, Peptide Bond Formation, and Amino Acid Polymerization are Hampered by Antibiotics
2004 StandoutNobel
STRUCTURAL INSIGHTS INTO TRANSLATIONAL FIDELITY
2005 StandoutNobel
Structural Insight into the Antibiotic Action of Telithromycin against Resistant Mutants
2003 StandoutNobel
Fidelity at the Molecular Level: Lessons from Protein Synthesis
2009
Macrolide antibiotic interaction and resistance on the bacterial ribosome.
2003
Works of A. Bashan being referenced
High Resolution Structure of the Large Ribosomal Subunit from a Mesophilic Eubacterium
2001 StandoutNobel
Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution
2000 StandoutNobel