Standout Papers
Citation Impact
Citing Papers
Brain monoglyceride lipase participating in endocannabinoid inactivation
2002
The endocannabinoid nervous system
2001
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
1990 StandoutNature
Pharmacology of Cannabinoid CB 1 and CB 2 Receptors
1997
Evaluation of Cannabinoid Receptor Agonists and Antagonists Using the Guanosine-5′-O-(3-[35S]thio)-triphosphate Binding Assay in Rat Cerebellar Membranes
1998
Comparative Receptor Binding Analyses of Cannabinoid Agonists and Antagonists
1998
Actions of Cannabinoids on Membrane Properties and Synaptic Transmission in Rat Periaqueductal Gray Neurons In Vitro
2000
Cannabinoid-Induced Hypotension and Bradycardia in Rats Is Mediated by CB1-Like Cannabinoid Receptors
1997
Activation of Cannabinoid Receptors in Rat Brain by WIN 55212-2 Produces Coupling to Multiple G Protein α-Subunits with Different Potencies
2000
Involvement of Dynorphin B in the Antinociceptive Effects of the Cannabinoid CP55,940 in the Spinal Cord
1997
Differential Blockade of the Antinociceptive Effects of Centrally Administered Cannabinoids by SR141716A
1998
Cannabinoid Transmission and Pain Perception
1998
The peripheral cannabinoid receptor: adenylate cyclase inhibition and G protein coupling
1995
Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia
2006
Cannabinoid pharmacology in the cardiovascular system: potential protective mechanisms through lipid signalling
2004
Assessment of Anandamide Interaction with the Cannabinoid Brain Receptor: SR 141716A Antagonism Studies in Mice and Autoradiographic Analysis of Receptor Binding in Rat Brain
1998
Cannabinoids modulate neuronal firing in the rat basolateral amygdala: evidence for CB1- and non-CB1-mediated actions
2003
Non-cannabinoid CB1, non-cannabinoid CB2 antinociceptive effects of several novel compounds in the PPQ stretch test in mice
2006
Cannabinoids and the immune system: Potential for the treatment of inflammatory diseases?
2005
Role of the endocannabinoid system in Alzheimer's disease: New perspectives
2004
International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors
2002 Standout
Activation of Cannabinoid CB2Receptors Suppresses C-Fiber Responses and Windup in Spinal Wide Dynamic Range Neurons in the Absence and Presence of Inflammation
2004
The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy
2003
Understanding Synapses: Past, Present, and Future
2008 StandoutNobel
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
2000 StandoutNature
The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes
2000
A peripheral cannabinoid mechanism suppresses spinal fos protein expression and pain behavior in a rat model of inflammation
2003
Δ9-Tetrahydrocannabinol discrimination in rats as a model for cannabis intoxication
1992
Modulation of anxiety through blockade of anandamide hydrolysis
2002 Standout
Cannabinoid physiology and pharmacology: 30 years of progress
2004
Selective Activation of Cannabinoid CB2 Receptors Suppresses Hyperalgesia Evoked by Intradermal Capsaicin
2004
Simultaneous Measurement of Anandamide and 2-Arachidonoylglycerol by Polymyxin B-Selective Adsorption and Subsequent High-Performance Liquid Chromatography Analysis: Increase in Endogenous Cannabinoids in the Sera of Patients with Endotoxic Shock
2001
Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide
2001
Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2‐arachidonoyl glycerol
2002
Brief presynaptic bursts evoke synapse-specific retrograde inhibition mediated by endogenous cannabinoids
2003
Endocrine Effects of Marijuana
2002
Spinal cannabinoids are anti-allodynic in rats with persistent inflammation
1999
The role of Cannabinoids in neurodegenerative diseases
2001
Brain Cannabinoid Systems as Targets for the Therapy of Neurological Disorders
1998
Cannabinoid 1 receptors are expressed in nociceptive primary sensory neurons
2000
A Selective Inverse Agonist for Central Cannabinoid Receptor Inhibits Mitogen-activated Protein Kinase Activation Stimulated by Insulin or Insulin-like Growth Factor 1
1997
Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naïve rats and in rat models of inflammatory and neuropathic pain
2004
Structural Requirements for Cannabinoid Receptor Probes
2005
Cannabinoid receptor activation inhibits GABAergic neurotransmission in rostral ventromedial medulla neurons in vitro
1999
Cannabinoid Receptor Expression in Immune Cells
1996
Endocannabinoid signaling system and brain reward: Emphasis on dopamine
2005
Cannabinoid analgesia
2002
Anandamide Amidohydrolase Activity in Rat Brain Microsomes
1995
Comparative analysis of fatty acid amide hydrolase and cb1 cannabinoid receptor expression in the mouse brain: evidence of a widespread role for fatty acid amide hydrolase in regulation of endocannabinoid signaling
2003
Adverse Health Effects of Marijuana Use
2014 Standout
Hypothalamic regulation of sleep and circadian rhythms
2005 StandoutNature
The cannabinoid CB1 receptor antagonist, SR141716A, selectively facilitates nociceptive responses of dorsal horn neurones in the rat
1999
Leptin-regulated endocannabinoids are involved in maintaining food intake
2001 Nature
Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry
1998
Immunocytochemical localization of cannabinoid CB1 receptor and fatty acid amide hydrolase in rat retina
1999
Cannabinoid receptor genes
1996
Antagonism of LPS and IFN-γ Induction of iNOS in Human Saphenous Vein Endothelium by Morphine and Anandamide by Nitric Oxide Inhibition of Adenylate Cyclase
1998
Anandamide, a Brain Endogenous Compound, Interacts Specifically with Cannabinoid Receptors and Inhibits Adenylate Cyclase
1993
CB1 cannabinoid receptors are enriched in the perisynaptic annulus and on preterminal segments of hippocampal GABAergic axons
2005
Drug Addiction, Dysregulation of Reward, and Allostasis
2001 Standout
Search for endogenous ligands of the cannabinoid receptor
1994
Central nervous system control of food intake and body weight
2006 StandoutNature
Expression of Cannabinoid Receptor mRNA in Murine and Human Leukocytes
1995
Endocannabinoid-Mediated Long-Term Plasticity Requires cAMP/PKA Signaling and RIM1α
2007 StandoutNobel
Evidence for functional CB1 cannabinoid receptor expressed in the rat thyroid
2002
Inhibition of anandamide hydrolysis in rat brain tissue by (E)‐6‐(bromomethylene) tetrahydro‐3‐(1‐naphthalenyl)‐2H‐pyran‐2‐one
1997
Control of pain initiation by endogenous cannabinoids
1998 StandoutNature
Differential distribution of functional cannabinoid CB1 receptors in the mouse gastroenteric tract
2003
Changes in cannabinoid CB1 receptors in striatal and cortical regions of rats with experimental allergic encephalomyelitis, an animal model of multiple sclerosis
2001
Neuroscience of Addiction
1998
Gilles de la Tourette-Syndrom
1997
Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
2008
Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system
1998
Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist
1993
Changes in CB1 receptors in motor-related brain structures of chronic relapsing experimental allergic encephalomyelitis mice
2006
Receptor-independent depression of DA and 5-HT uptake by cannabinoids in rat neocortex—involvement of Na+/K+-ATPase
2003
Endocannabinoids
1998
Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain
2006
Biphasic modulation of voltage-dependent currents of retinal cones by cannabinoid CB1 receptor agonist WIN 55212-2
2003
The cannabinoid agonists WIN 55,212-2 and CP 55,940 attenuate rotational behavior induced by a dopamine D1 but not a D2 agonist in rats with unilateral lesions of the nigrostriatal pathway
1995
Inhibition of noxious stimulus-evoked activity of spinal cord dorsal horn neurons by the cannabinoid WIN 55,212-2
1995
Effect of Chronic Administration of R-(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone Mesylate (WIN55,212-2) or Δ9-Tetrahydrocannabinol on Cannabinoid Receptor Adaptation in Mice
2002
Inverse agonist properties of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide HCl (SR141716A) and 1-(2-chlorophenyl)-4-cyano-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxylic acid phenylamide (CP-272871) for the CB1 cannabinoid receptor
2000
The endogenous cannabinoid receptor ligand, anandamide, inhibits the motor behavior: role of nigrostriatal dopaminergic neurons
1995
Agonist efficacy and receptor efficiency in heterozygous CB1 knockout mice: relationship of reduced CB1 receptor density to G‐protein activation
2001
Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity
2001
The Cannabinoid Receptor Agonist WIN 55,212-2 Reduces D2, but Not D1, Dopamine Receptor-Mediated Alleviation of Akinesia in the Reserpine-Treated Rat Model of Parkinson's Disease
1997
ETHANOL INDUCES HIGHER BEC IN CB1 CANNABINOID RECEPTOR KNOCKOUT MICE WHILE DECREASING ETHANOL PREFERENCE
2004
Isotope Dilution Mass Spectrometric Measurements Indicate That Arachidonylethanolamide, the Proposed Endogenous Ligand of the Cannabinoid Receptor, Accumulates in Rat Brain Tissue Post Mortem but Is Contained at Low Levels in or Is Absent from Fresh Tissue
1996
Cannabinoid receptor type 2 gene is associated with human osteoporosis
2005
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus
2001
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
1996 StandoutNature
Molecular Neurobiology of The Cannabinoid Receptor
1996
Molecular characterization of a peripheral receptor for cannabinoids
1993 StandoutNature
The cannabinoid receptor antagonist SR-141716A induces penile erection in male rats: Involvement of paraventricular glutamic acid and nitric oxide
2005
Control of Ca2+ influx by cannabinoid and metabotropic glutamate receptors in rat cerebellar cortex requires K+ channels
2001
Pharmacological and biochemical interactions between opioids and cannabinoids
1999
Cannabinoids as therapeutic agents in cardiovascular disease: a tale of passions and illusions
2007
Prevention of Alzheimer's Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation
2005
Cannabinoid receptor-mediated inhibition of the rat tail-flick reflex after microinjection into the rostral ventromedial medulla
1998
Adolescent exposure to cannabinoids induces long-Lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons
2004
Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: Relevance to Parkinson's disease
2005
Aversive effects of the synthetic cannabinoid CP 55,940 in rats
1996
The endocannabinoid system in the basal ganglia and in the mesolimbic reward system: implications for neurological and psychiatric disorders
2003
Localization of cannabinoid receptor mRNA in rat brain
1993
Delta-9-tetrahydrocannabinol differentially suppresses cisplatin-induced emesis and indices of motor function via cannabinoid CB1 receptors in the least shrew
2001
Endocannabinoids in the immune system and cancer
2002
Immunohistochemical localization of the neural cannabinoid receptor in rat brain
1998
Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors
1997
CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain
2002
The Influence of Marijuana Use on Neurocognitive Functioning in Adolescents
2008
Cannabinoids attenuate capsaicin-evoked hyperalgesia through spinal and peripheral mechanisms
2001
Activation of G-proteins in brain by endogenous and exogenous cannabinoids
2006
Distribution of neuronal cannabinoid receptor in the adult rat brain: A comparative receptor binding radioautography and in situ hybridization histochemistry
1992
Dopamine activation of endogenous cannabinoid signaling in dorsal striatum
1999
Cannabinoids, hippocampal function and memory
1999
Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations
2000
The Presynaptic Active Zone
2012 StandoutNobel
Cannabis in Movement Disorders
1999
The Protective Role of the Hypothalamic‐Pituitary‐Adrenal Axis against Lethality Produced by Immune, Infectious, and Inflammatory Stress
1995
Cannabinoids: possible role in patho‐physiology and therapy of Gilles de la Tourette syndrome
1998
Molecular biology of cannabinoid receptors
2002
Cannabinoid hyperemesis: cyclical hyperemesis in association with chronic cannabis abuse
2004
Loss of cannabinoid CB1 receptors in the basal ganglia in the late akinetic phase of rats with experimental Huntington’s disease
2002
Levodopa treatment reverses endocannabinoid system abnormalities in experimental parkinsonism
2003
Reversible and regionally selective downregulation of brain cannabinoid CB1 receptors in chronic daily cannabis smokers
2011
Effects of cannabinoid receptor agonists on neuronally‐evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human
2000
Towards a Cannabinoid Hypothesis of Schizophrenia: Cognitive Impairments Due to Dysregulation of the Endogenous Cannabinoid System
1997
Cognitive Functioning of Long-term Heavy Cannabis Users Seeking Treatment
2002
Activation of spinal cannabinoid 1 receptors inhibits C‐fibre driven hyperexcitable neuronal responses and increases [35S]GTPγS binding in the dorsal horn of the spinal cord of noninflamed and inflamed rats
2000
Anandamide content is increased and CB1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia
2004
Targeting the cannabinoid system for pain relief?
2013
Ipsilateral turning behavior induced by unilateral microinjections of a cannabinoid into the rat subthalamic nucleus
1998
Delta 9-Tetrahydrocannabinol (THC) is Effective in the Treatment of Tics in Tourette Syndrome
2003
Cannabinoid CB1 antagonists possess antiparkinsonian efficacy only in rats with very severe nigral lesion in experimental parkinsonism
2005
Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1receptors on peripheral sympathetic nerves
1996
Morphine and anandamide coupling to nitric oxide stimulates GnRH and CRF release from rat median eminence: neurovascular regulation
1998
The Psychotomimetic Effects of Intravenous Delta-9-Tetrahydrocannabinol in Healthy Individuals: Implications for Psychosis
2004
Despite substantial degradation, 2‐arachidonoylglycerol is a potent full efficacy agonist mediating CB1 receptor‐dependent G‐protein activation in rat cerebellar membranes
2001
Motor actions of cannabinoids in the basal ganglia output nuclei
1999
Modulation of GABAergic transmission in the globus pallidus by the synthetic cannabinoid WIN 55,212-2
1996
Cannabinoid Receptor Signaling
2005
Effects of cannabinoid receptor‐2 activation on accelerated gastrointestinal transit in lipopolysaccharide‐treated rats
2004
Retrograde signaling in the regulation of synaptic transmission: focus on endocannabinoids
2002
Cannabinoid effects in basal ganglia in a rat model of Parkinson's disease
1998
Stimulation of Cannabinoid Receptor CB1 Induces krox-24 Expression in Human Astrocytoma Cells
1995
Fatty Acid Sulfonyl Fluorides Inhibit Anandamide Metabolism and Bind to the Cannabinoid Receptor
1997
Motivational Effects of Cannabinoids and Opioids on Food Reinforcement Depend on Simultaneous Activation of Cannabinoid and Opioid Systems
2005
Presynaptic mechanisms underlying cannabinoid inhibition of excitatory synaptic transmission in rat striatal neurons
2001
Antidepressant-like and anorectic effects of the cannabinoid CB1 receptor inverse agonist AM251 in mice
2003
Cannabinoid CB1 receptors in the basal ganglia and motor response to activation or blockade of these receptors in parkin-null mice
2005
Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine
2002
Central and peripheral mechanisms contribute to the antiemetic actions of delta-9-tetrahydrocannabinol against 5-hydroxytryptophan-induced emesis
2004
Neurobiology of marijuana abuse
1992
Involvement of CB1 cannabinoid receptors in emotional behaviour
2002
Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia
2005
Inhibitory effects of SR141716A on G-protein activation in rat brain
2001
Activation of inwardly rectifying potassium channels (GIRK1) by co-expressed rat brain cannabinoid receptors in Xenopus oocytes
1995
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
A second endogenous cannabinoid that modulates long-term potentiation
1997 Nature
Cannabinoid Control of Motor Function at the Basal Ganglia
2005
Genetic Impairment of Frontocortical Endocannabinoid Degradation and High Alcohol Preference
2006
Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling
2013 StandoutNobel
Dual Modulation of Endocannabinoid Transport and Fatty Acid Amide Hydrolase Protects against Excitotoxicity
2005
Binding of the non-classical cannabinoid CP 55,940, and the diarylpyrazole AM251 to rodent brain cannabinoid receptors
1997
Δ9-Tetrahydrocannabinol Acts as a Partial Agonist to Modulate Glutamatergic Synaptic Transmission between Rat Hippocampal Neurons in Culture
1999
Cannabinoid CB1 receptors control conditioned drug seeking
2005
Cannabinoids and Multiple Sclerosis
2007
Unilateral 6-hydroxydopamine lesions of nigrostriatal dopaminergic neurons increased CB1 receptor mRNA levels in the caudate-putamen
2000
Δ9-Tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism
1996
Time-course of the effects of anandamide, the putative endogenous cannabinoid receptor ligand, on extrapyramidal function
1995
Behavioural and biochemical evidence for signs of abstinence in mice chronically treated with Δ‐9‐tetrahydrocannabinol
1998
Dopaminergic Regulation of Cannabinoid Receptor mRNA Levels in the Rat Caudate‐Plitamen: An In Situ Hybridization Study
1993
Cannabinoid Inhibition of Adenylate Cyclase-mediated Signal Transduction and Interleukin 2 (IL-2) Expression in the Murine T-cell Line, EL4.IL-2
1996
Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects
2001
Functional expression of cell surface cannabinoid CB1 receptors on presynaptic inhibitory terminals in cultured rat hippocampal neurons
2000
Pharmacology of Cannabinoid Receptors
1995
Different mechanisms for dopaminergic excitation induced by opiates and cannabinoids in the rat midbrain
2000
Endogenous Cannabinoids Mediate Retrograde Signals from Depolarized Postsynaptic Neurons to Presynaptic Terminals
2001
SR 141716A enhances spatial memory as assessed in a radial-arm maze task in rats
2000
Novelty and Anxiolytic Drugs Dissociate Two Components of Hippocampal Theta in Behaving Rats
2013 StandoutNobel
Involvement of vanilloid-like receptors in the effects of anandamide on motor behavior and nigrostriatal dopaminergic activity: in vivo and in vitro evidence
2004
An Amino-terminal Variant of the Central Cannabinoid Receptor Resulting from Alternative Splicing
1995
The Endocannabinoid Anandamide Protects Neurons during CNS Inflammation by Induction of MKP-1 in Microglial Cells
2006
The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families
1998 StandoutNobel
Regulation of Gonadotropin-Releasing Hormone Secretion by Cannabinoids
2005
Central nervous system control of food intake
2000 StandoutNature
Cannabinoid Modulation of Opiate Reinforcement through the Ventral Striatopallidal Pathway
2005
Differential expression of orexin receptors 1 and 2 in the rat brain
2001
Unconditioned and conditioned anxiogenic effects of the cannabinoid receptor agonist CP 55,940 in the social interaction test
2004
Presynaptic Inhibition Caused by Retrograde Signal from Metabotropic Glutamate to Cannabinoid Receptors
2001
Evidence That 2-Arachidonoylglycerol but Not N-Palmitoylethanolamine or Anandamide Is the Physiological Ligand for the Cannabinoid CB2 Receptor
2000
Effect of the cannabinoid receptor SPECT agent, AM 281, on hippocampal acetylcholine release from rat brain slices
1997
Randomised, double‐blind, placebo‐controlled trial to assess the potential of cannabinoid receptor stimulation in the treatment of dystonia
2002
Physiological and behavioural effects of the endogenous cannabinoid, arachidonylethanolamide (anandamide), in the rat
1996
GABAergic interneurons are the targets of cannabinoid actions in the human hippocampus
2000
Expression of Central and Peripheral Cannabinoid Receptors in Human Immune Tissues and Leukocyte Subpopulations
1995
Lack of CB1 Cannabinoid Receptor Impairs Cocaine Self-Administration
2005
Localization of cannabinoid receptor in the human developing and adult basal ganglia. Higher levels in the striatonigral neurons
1992
Cannabinoid receptor stimulation of guanosine-5′-O-(3-[35S]thio)triphosphate binding in rat brain membranes
1996
Neuronal localization of cannabinoid receptors in the basal ganglia of the rat
1991
Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide
1995
Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain
1999
Two Brain Sites for Cannabinoid Reward
2006
Arachidonylethanolamide (AEA) activation of FOS proto-oncogene protein immunoreactivity in the rat brain
1998
Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation
2002
Cannabinoid Receptors and Their Relationships with Neuropsychiatric Disorders
2005
Cannabinoid receptors and pain
2001
Role of the Endogenous Cannabinoid System in the Regulation of Motor Activity
1998
Cannabinoid receptor messenger RNA levels decrease in a subset of neurons of the lateral striatum, cortex and hippocampus of transgenic Huntington’s disease mice
2000
Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB2 receptor
2000
Cannabinoid Action Depends on Phosphorylation of Dopamine- and cAMP-Regulated Phosphoprotein of 32 kDa at the Protein Kinase A Site in Striatal Projection Neurons
2005
Design and synthesis of the CB1 selective cannabinoid antagonist AM281: A potential human SPECT ligand
1999
Anandamide Enhances Extracellular Levels of Adenosine and Induces Sleep: An In Vivo Microdialysis Study
2003
The endogenous cannabinoid system and the basal ganglia
2002
Opioid and cannabinoid receptor-mediated regulation of the increase in adrenocorticotropin hormone and corticosterone plasma concentrations induced by central administration of Δ9-tetrahydrocannabinol in rats
1999
Cannabinoids decrease excitatory synaptic transmission and impair long‐term depression in rat cerebellar Purkinje cells
1998
Analogues and homologues of N-palmitoylethanolamide, a putative endogenous CB2 cannabinoid, as potential ligands for the cannabinoid receptors
1999
Effects of levodopa on endocannabinoid levels in rat basal ganglia: implications for the treatment of levodopa‐induced dyskinesias
2003
Cannabinoids: potential anticancer agents
2003
Cannabinoid modulation of wide dynamic range neurons in the lumbar dorsal horn of the rat by spinally administered WIN55,212-2
1998
Central effects of the cannabinoid receptor agonist WIN55212‐2 on respiratory and cardiovascular regulation in anaesthetised rats
2004
Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain
1997
Levels, Metabolism, and Pharmacological Activity of Anandamide in CB1 Cannabinoid Receptor Knockout Mice
2000
Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus
2005
Overexpression of cannabinoid receptors CB1 and CB2 correlates with improved prognosis of patients with hepatocellular carcinoma
2006
Clozapine decreases [3H] CP 55940 binding to the cannabinoid1 receptor in the rat nucleus accumbens
2005
The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9‐tetrahydrocannabinol, cannabidiol and Δ9‐tetrahydrocannabivarin
2007 Standout
Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain
2006
A Randomized, Placebo-Controlled, Crossover Trial of Cannabis Cigarettes in Neuropathic Pain
2008
Cannabinoid CB1 receptors are localized primarily on cholecystokinin-containing GABAergic interneurons in the rat hippocampal formation
1999
Localization of CB 1 -cannabinoid receptor immunoreactivity in the porcine enteric nervous system
2000
Selective activation of cannabinoid CB2 receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation
2003
Suppression of noxious stimulus-evoked expression of fos protein-like immunoreactivity in rat spinal cord by a selective cannabinoid agonist
1996
Differential Regulation of Synaptic Inputs by Constitutively Released Endocannabinoids and Exogenous Cannabinoids
2005
The human eye expresses high levels of CB1 cannabinoid receptor mRNA and protein
2000
Modulation of Neurotransmission by Cannabinoids in the Basal Ganglia
1997
Endocannabinoid lipids and mediated system: Implications for alcoholism and neuropsychiatric disorders
2005
Δ9-Tetrahydrocannabinol decreases extracellular GABA and increases extracellular glutamate and dopamine levels in the rat prefrontal cortex: an in vivo microdialysis study
2002
Regulation of cannabinoid and mu opioid receptors in rat lumbar spinal cord following neonatal capsaicin treatment
1998
Pharmacology of cannabinoid CB1 and CB2 receptors
1997
Locomotor activity and occupancy of brain cannabinoid CB1 receptors by the antagonist/inverse agonist AM281
2000
Effects of systemic 3-nitropropionic acid-induced lesions of the dorsal striatum on cannabinoid and µ-opioid receptor binding in the basal ganglia
2000
Antagonism of cannabinoid CB1 receptors in the paraventricular nucleus of male rats induces penile erection
2004
CNR1, central cannabinoid receptor gene, associated with susceptibility to hebephrenic schizophrenia
2002
Cannabinoids in Multiple Sclerosis
2004
Cannabinoid receptors and the regulation of immune response
2000
Endocannabinoids at the synapse a decade after the dies mirabilis (29 March 2001): what we still do not know
2012
Local pressure application of cannabinoid agonists increases spontaneous activity of rat substantia nigra pars reticulata neurons without affecting response to iontophoretically-applied GABA
1996
CB1 cannabinoid receptors mediate anxiolytic effects: convergent genetic and pharmacological evidence with CB1-specific agents
2004
Suppression of the humoral immune response by cannabinoids is partially mediated through inhibition of adenylate cyclase by a pertussis toxin-sensitive G-protein coupled mechanism
1994
What we can do and what we cannot do with fMRI
2008 StandoutNature
Down-regulation of cannabinoid receptor agonist-stimulated [ ]GTPγS binding in synaptic plasma membrane from chronic ethanol exposed mouse
1999
Cannabinoid receptor CB1 activates the Na+/H+ exchanger NHE‐1 isoform via Gi‐mediated mitogen activated protein kinase signaling transduction pathways
1999
Effects on the Immune System
2005
Thermogenic and corticosterone responses to intravenous cytokines (IL-1β and TNF-α) are attenuated by subdiaphragmatic vagotomy
1998
Inhibition of hippocampal acetylcholine release after acute and repeated Δ9-tetrahydrocannabinol in rats
1998
Reduction of opioid dependence by the CB1 antagonist SR141716A in mice: evaluation of the interest in pharmacotherapy of opioid addiction
2001
Coexpression of the cannabinoid receptor type 1 with the corticotropin-releasing hormone receptor type 1 in distinct regions of the adult mouse forebrain
2004
Localization of cannabinoid CB1 receptor mRNA in neuronal subpopulations of rat striatum: A double-label in situ hybridization study
2000
Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors
1998
Antihyperalgesic effects of spinal cannabinoids
1998
Cannabinoids and the Digestive Tract
2005
Disruption of CB1 receptor signaling impairs extinction of spatial memory in mice
2004
Characterization of the effects of cannabinoids on guinea‐pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves
2000
Action of δ-9-tetrahydrocannabinol on gabaa receptor-mediated responses in a grease-gap recording preparation of the rat hippocampal slice
1997
Mechanisms underlying cannabinoid inhibition of presynaptic Ca2+ influx at parallel fibre synapses of the rat cerebellum
2004
Hypersensitization of the Orexin 1 Receptor by the CB1 Receptor
2003
An endocannabinoid mechanism for stress-induced analgesia
2005 Nature
An examination of the central sites of action of cannabinoid-induced antinociception in the rat
1995
Origin and physiological roles of inflammation
2008 StandoutNature
Anatomical basis for cannabinoid-induced antinociception as revealed by intracerebral microinjections
1999
Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents
1993 Nobel
The molecular logic of endocannabinoid signalling
2003 Standout
The evidence for the existence of cannabinoid receptors
1993
Regulation of Peripheral Cannabinoid Receptor CB2Phosphorylation by the Inverse Agonist SR 144528
1999
Distribution of cannabinoid receptors in rat brain determined with aminoalkylindoles
1992
Identification of cannabinoid receptors in cultures of rat cerebellar granule cells
1993
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
Changes in Rat Spleen Cannabinoid Receptors after Chronic CP-55,940: An Autoradiographic Study
1997
Localization of the CB1 type cannabinoid receptor in the rat basolateral amygdala: high concentrations in a subpopulation of cholecystokinin-containing interneurons
2001
Retrograde signaling by endocannabinoids
2002
Localization of drug reward mechanisms by intracranial injections
1992
Evaluation of CB1 Receptor Knockout Mice in the Morris Water Maze
2002
Loss of cannabinoid receptor binding and messenger RNA levels and cannabinoid agonist-stimulated [35s]guanylyl-5′-O-(thio)-triphosphate binding in the basal ganglia of aged rats
1998
Overlap between the ligand recognition properties of the anandamide transporter and the VR1 vanilloid receptor: inhibitors of anandamide uptake with negligible capsaicin‐like activity
2000
Role of the endogenous cannabinoid system as a modulator of dopamine transmission: Implications for Parkinson’s disease and schizophrenia
2001
Obesity and the Regulation of Energy Balance
2001 Standout
THE ACTIVATION OF CANNABINOID RECEPTORS IN STRIATONIGRAL GABAERGIC NEURONS INHIBITED GABA UPTAKE
1997
Evidence for the presence of CB2-like cannabinoid receptors on peripheral nerve terminals
1997
Effects of topical anandamides on intraocular pressure in normotensive rabbits
1996
Cannabinoid Receptor Agonists Protect Cultured Rat Hippocampal Neurons from Excitotoxicity
1998
Cannabis-Associated Psychosis
2004
Comparison of cannabinoid binding sites in guinea‐pig forebrain and small intestine
1998
CB2 cannabinoid receptor-mediated peripheral antinociception
2001
Direct inhibition by cannabinoids of human 5‐HT3A receptors: probable involvement of an allosteric modulatory site
2002
Interneuron Diversity series: Rhythm and mood in perisomatic inhibition
2003
Endocannabinoids and related fatty acid derivatives in pain modulation
2002
Lack of response suppression follows repeated ventral tegmental cannabinoid administration: an in vitro electrophysiological study
2000
Cannabinoid receptors undergo axonal flow in sensory nerves
1999
Further evidence for the presence of cannabinoid CB1 receptors in guinea‐pig small intestine
1996
Trpv1 Reporter Mice Reveal Highly Restricted Brain Distribution and Functional Expression in Arteriolar Smooth Muscle Cells
2011 StandoutNobel
Cannabinoids and multiple sclerosis
2002
Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs
1991
Molecular mechanisms involved in the asymmetric interaction between cannabinoid and opioid systems
2005
Type-1 Cannabinoid Receptor Signaling in Neuronal Development
2012
Endocannabinoid-Mediated Control of Synaptic Transmission
2009
Selective vulnerability in Huntington's disease: Preferential loss of cannabinoid receptors in lateral globus pallidus
1994
Neuromodulatory role of the endocannabinoid signaling system in alcoholism: an overview
2002
Role of endocannabinoid system in mental diseases
2004
Loss of cannabinoid receptors in the substantia nigra in huntington's disease
1993
Effects of anandamide on cannabinoid receptors in rat brain membranes
1994
Leptin and the regulation of body weight in mammals
1998 StandoutNature
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
1995 Standout
Reversal of Δ9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine
2002
Stimulation of cannabinoid receptors reduces levodopa‐induced dyskinesia in the MPTP‐lesioned nonhuman primate model of Parkinson's disease
2002
The effects of cannabinoids on the brain
1999
Cannabinoids inhibit excitatory neurotransmission in the substantia nigra pars reticulata
2000
Cannabinoid receptors on goldfish retinal bipolar cells: Electron-microscope immunocytochemistry and whole-cell recordings
2000
Systemic or intrahippocampal cannabinoid administration impairs spatial memory in rats
1995
Endocannabinoid system and opioid addiction: Behavioural aspects
2005
Effects of SR141716A, a central cannabinoid receptor antagonist, on food-maintained responding
2000
The inflammatory reflex
2002 StandoutNature
Treatment of Tourette Syndrome with Delta-9-Tetrahydrocannabinol (Δ9-THC): No Influence on Neuropsychological Performance
2003
(—)-Δ9-Tetrahydrocannabinol Antagonizes the Peripheral Cannabinoid Receptor-mediated Inhibition of Adenylyl Cyclase
1996
Chronic (−)-Δ9-tetrahydrocannabinol treatment induces sensitization to the psychomotor effects of amphetamine in rats
1999
Retrograde Inhibition of Presynaptic Calcium Influx by Endogenous Cannabinoids at Excitatory Synapses onto Purkinje Cells
2001
Molecular and cellular basis of cannabinoid and opioid interactions
2005
Endocannabinoids in the regulation of appetite and body weight
2005
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
Identification and characterisation of a novel splice variant of the human CB1 receptor
2004
Endocannabinoids affect neurological and cognitive function in thioacetamide-induced hepatic encephalopathy in mice
2005
THE CANNABINOID AGONIST HU 210 MODIFIES RAT BEHAVIOURAL RESPONSES TO NOVELTY AND STRESS
2000
Segregation of two endocannabinoid‐hydrolyzing enzymes into pre‐ and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala
2004
Cannabinoid modulation of drug reward and the implications of marijuana legalization
2014
Cannabinoid receptor binding and messenger RNA expression in human brain: An in vitro receptor autoradiography and in situ hybridization histochemistry study of normal aged and Alzheimer's brains
1994
Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behaviors in rats
2003
A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation
2002
Parvalbumin neurons and gamma rhythms enhance cortical circuit performance
2009 StandoutNature
CB2 receptor‐mediated antihyperalgesia: possible direct involvement of neural mechanisms
2006
Endocannabinoid system and stress and anxiety responses
2005
Involvement of the opioid system in the anxiolytic-like effects induced by Δ9-tetrahydrocannabinol
2002
Cerebrospinal Anandamide Levels are Elevated in Acute Schizophrenia and are Inversely Correlated with Psychotic Symptoms
2004
Examination of the effect of the cannabinoid receptor agonist, CP 55,940, on electrically evoked transmitter release from rat brain slices
1997
Evidence for novel cannabinoid receptors
2005
Formation and inactivation of endogenous cannabinoid anandamide in central neurons
1994 StandoutNature
Assessment of cannabinoid induced gene changes: tolerance and neuroprotection
2002
Functional consequences of the acute administration of the cannabinoid receptor antagonist, SR141716A, in cannabinoid-naive and -tolerant animals: a quantitative 2-[14C]deoxyglucose study
2003
Endocannabinoids and the gut
2002
Cannabinoid-induced antinociception is mediated by a spinalα2-noradrenergic mechanism
1991
Synthesis and Characterization of NESS 0327: A Novel Putative Antagonist of the CB1 Cannabinoid Receptor
2003
A random walk through a cannabis field
1991
Cannabinoid actions on rat superficial medullary dorsal horn neurons in vitro
2001
Cannabis use for chronic non-cancer pain: results of a prospective survey
2003
Downregulation of Endocannabinoid Signaling in the Hippocampus Following Chronic Unpredictable Stress
2004
Loss of mRNA levels, binding and activation of GTP-binding proteins for cannabinoid CB1 receptors in the basal ganglia of a transgenic model of Huntington’s disease
2002
Cannabis, cannabinoids and reproduction
2003
Inhibitory effects of certain enantiomeric cannabinoids in the mouse vas deferens and the myenteric plexus preparation of guinea‐pig small intestine
1992
The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABAA receptor alterations in the human basal ganglia in Huntington's disease
2000
Pre- and postsynaptic distribution of cannabinoid and mu opioid receptors in rat spinal cord
1999
Human Studies of Cannabinoids and Medicinal Cannabis
2005
Leptin Inhibits Bone Formation through a Hypothalamic Relay
2000 Standout
The cannabinoid receptor antagonist SR�141716 attenuates overfeeding induced by systemic or intracranial morphine
2003
The CB2 cannabinoid agonist AM‐1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset
2007
Δ9-tetrahydrocannabinol and anandamide enhance the ability of muscimol to induce catalepsy in the globus pallidus of rats
1993
Cannabinoid Receptor Agonist Efficacy for Stimulating [35S]GTPγS Binding to Rat Cerebellar Membranes Correlates with Agonist-induced Decreases in GDP Affinity
1998
The Cannabinoid Receptor Agonist WIN 55,212-2 Regulates Glutamate Transmission in Rat Cerebral Cortex: an In Vivo and In Vitro Study
2001
Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT3AReceptor Subunit
2004 StandoutNobel
Therapeutic Potential of Cannabinoids in CNS Disease
2003
Cannabinoid receptor CB1 mRNA is highly expressed in the rat ciliary body: implications for the antiglaucoma properties of marihuana
1998
Synthesis and Characterization of Potent and Selective Agonists of the Neuronal Cannabinoid Receptor (CB1)
1999
Identification of a functionally relevant cannabinoid receptor on mouse spleen cells that is involved in cannabinoid-mediated immune modulation.
1992
Δ9-Tetrahydrocannabinol Acts as a Partial Agonist to Modulate Glutamatergic Synaptic Transmission between Rat Hippocampal Neurons in Culture
1999
Cannabinoid Inhibition of the Processing of Intact Lysozyme by Macrophages: Evidence for CB2 Receptor Participation
1999
Functional Role of High-Affinity Anandamide Transport, as Revealed by Selective Inhibition
1997 Science
CANNABINOID RECEPTORS AND THEIR ENDOGENOUS AGONISTS
1998
A Neural Substrate of Prediction and Reward
1997 StandoutScience
Altered gene expression in striatal projection neurons in CB1 cannabinoid receptor knockout mice
1999
Experimental Parkinsonism Alters Endocannabinoid Degradation: Implications for Striatal Glutamatergic Transmission
2002
Role of cyclic AMP in the actions of cannabinoid receptors
1996
Cannabis: pharmacology and toxicology in animals and humans
1996
Regional Differences in Cannabinoid Receptor/G-protein Coupling in Rat Brain
1997
The therapeutic potential of the cannabinoids in neuroprotection
2002
Biology of Reproduction Highlights …
2005
Cannabis: pharmacology and toxicology in animals and humans
1996
Endogenous cannabinoids and appetite.
2001
The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance
2005
A new form of cerebellar long-term potentiation is postsynaptic and depends on nitric oxide but not cAMP
2002 StandoutNobel
Therapeutic potential of cannabinoid receptor agonists as analgesic agents
2005
The neurobiology and evolution of cannabinoid signalling
2001
Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB 1 Receptor Knockout Mice
1999 StandoutScience
In Vitro and in Vivo Pharmacological Characterization of JTE-907, a Novel Selective Ligand for Cannabinoid CB2 Receptor
2001
In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding.
1995
Mechanisms of Cannabinoid Inhibition of GABAASynaptic Transmission in the Hippocampus
2000
Occurrence and Biosynthesis of Endogenous Cannabinoid Precursor,N-Arachidonoyl Phosphatidylethanolamine, in Rat Brain
1997
Effects of cannabinoids on the anxiety-like response in mice.
2006
Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance
1998
The Cannabinoid CB1 Receptor Mediates Retrograde Signals for Depolarization-Induced Suppression of Inhibition in Cerebellar Purkinje Cells
2002
Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide.
1995
Neurobiological consequences of maternal cannabis on human fetal development and its neuropsychiatric outcome
2009
Distributions of leptin receptor mRNA isoforms in the rat brain
1998
Cannabinoid Suppression of Noxious Heat-Evoked Activity in Wide Dynamic Range Neurons in the Lumbar Dorsal Horn of the Rat
1999
A new perspective on cannabinoid signalling: complimentary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain.
1998
Treatment of Tourette’s Syndrome With Delta-9-Tetrahydrocannabinol
1999
Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses
2001 Nature
Presynaptic Cannabinoid Sensitivity Is a Major Determinant of Depolarization-Induced Retrograde Suppression at Hippocampal Synapses
2002
Endocannabinoid Signaling and Long-Term Synaptic Plasticity
2009
Effects of Cannabinoid Receptor Agonist and Antagonist Ligands on Production of Inflammatory Cytokines and Anti-Inflammatory Interleukin-10 in Endotoxemic Mice
2000
Cannabinoid CB1 receptors and ligands in vertebrate retina: Localization and function of an endogenous signaling system
1999
Cannabinoids Modulate Synaptic Strength and Plasticity at Glutamatergic Synapses of Rat Prefrontal Cortex Pyramidal Neurons
2000
Delta-9-tetrahydrocannabinol effects in schizophrenia: Implications for cognition, psychosis, and addiction
2005
Role of Endogenous Cannabinoids in Synaptic Signaling
2003
Cannabinoid Analgesia as a Potential New Therapeutic Option in the Treatment of Chronic Pain
2006
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
Cannabinoid receptor agonists inhibit depolarization‐induced calcium influx in cerebellar granule neurons
2001
Novel Analogues of Arachidonylethanolamide (Anandamide): Affinities for the CB1 and CB2 Cannabinoid Receptors and Metabolic Stability
1998
Localization of cannabinoid CB1 receptors in the human anterior eye and retina.
1999
Modulation and Functional Involvement of CB2 Peripheral Cannabinoid Receptors During B-Cell Differentiation
1998
LY320135, a Novel Cannabinoid CB1 Receptor Antagonist, Unmasks Coupling of the CB1 Receptor to Stimulation of cAMP Accumulation
1998
Reversal of Dopamine D2Receptor Responses by an Anandamide Transport Inhibitor
2000
Cloning and Pharmacological Characterization of the Rat CB2 Cannabinoid Receptor
2000
Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction.
1993
Ultrastructural Localization of the CB1 Cannabinoid Receptor in μ-Opioid Receptor Patches of the Rat Caudate Putamen Nucleus
2001
Activation of Corticotropin-Releasing Factor in the Limbic System During Cannabinoid Withdrawal
1997 Science
The contribution of the vagus nerve in interleukin-1β-induced fever is dependent on dose
2001
Effects of Chronic Treatment with Δ9-Tetrahydrocannabinol on Cannabinoid-Stimulated [35S]GTPγS Autoradiography in Rat Brain
1996
Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation
1997
Direct Actions of Cannabinoids on Synaptic Transmission in the Nucleus Accumbens: A Comparison With Opioids
2001
Therapeutic Action of Cannabinoids in a Murine Model of Multiple Sclerosis
2003
Mechanism of Cannabinoid Effects on Long-Term Potentiation and Depression in Hippocampal CA1 Neurons
1999
Functional Tolerance and Blockade of Long-Term Depression at Synapses in the Nucleus Accumbens after Chronic Cannabinoid Exposure
2003
Cannabinoids Inhibit N- and P/Q-Type Calcium Channels in Cultured Rat Hippocampal Neurons
1997
Effects of Cannabinoids on Sympathetic and Parasympathetic Neuroeffector Transmission in the Rabbit Heart
2001
Drug Abuse: Hedonic Homeostatic Dysregulation
1997 StandoutScience
Functional Interaction between Opioid and Cannabinoid Receptors in Drug Self-Administration
2001
Suppression of Noxious Stimulus-Evoked Activity in the Ventral Posterolateral Nucleus of the Thalamus by a Cannabinoid Agonist: Correlation between Electrophysiological and Antinociceptive Effects
1996
Cannabinoid-Induced Presynaptic Inhibition of Glutamatergic EPSCs in Substantia Gelatinosa Neurons of the Rat Spinal Cord
2001
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons.
1996
Cannabinoid CB1 receptor knockout mice exhibit markedly reduced voluntary alcohol consumption and lack alcohol‐induced dopamine release in the nucleus accumbens
2003
HU-308: A specific agonist for CB 2 , a peripheral cannabinoid receptor
1999
Endocannabinoid Signaling in the Brain
2002 Science
Marijuana and cannabinoid regulation of brain reward circuits
2004
The Science of Marijuana
2007
Cannabinoids and the gastrointestinal tract
2001
Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors.
1997
Increasing cannabinoid levels by pharmacological and genetic manipulation delays disease progression in SOD1 mice
2006
Localisation of cannabinoid receptors in the rat brain using antibodies to the intracellular C-terminal tail of CB1
2000
Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning
2011 StandoutNobel
Protective effects of cannabinoid receptor agonists against cocaine and other convulsant-induced toxic behavioural symptoms
2001
Δ9-Tetrahydrocannabinol Treatment Suppresses Immunity and Early IFN-γ, IL-12, and IL-12 Receptor β2 Responses toLegionella pneumophilaInfection
2000
A Peripheral Mechanism for CB1 Cannabinoid Receptor-Dependent Modulation of Feeding
2002
Cannabinoid Receptors Can Activate and Inhibit G Protein-Coupled Inwardly Rectifying Potassium Channels in a Xenopus Oocyte Expression System
1999
Short-Term Retrograde Inhibition of GABAergic Synaptic Currents in Rat Purkinje Cells Is Mediated by Endogenous Cannabinoids
2002
Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor
1992 StandoutScience
Cannabinoid Receptor Agonists Inhibit Glutamatergic Synaptic Transmission in Rat Hippocampal Cultures
1996
Presynaptically Located CB1 Cannabinoid Receptors Regulate GABA Release from Axon Terminals of Specific Hippocampal Interneurons
1999 Standout
Activation of CB 2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS
2003
SR 144528, an Antagonist for the Peripheral Cannabinoid Receptor that Behaves as an Inverse Agonist
1999
Cannabinoids Promote Oligodendrocyte Progenitor Survival: Involvement of Cannabinoid Receptors and Phosphatidylinositol-3 Kinase/Akt Signaling
2002
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells.
1992
Effects of intrapallidal cannabinoids on rotational behavior in rats: Interactions with the dopaminergic system
1998
Pain modulation by release of the endogenous cannabinoid anandamide
1999
Concurrent Stimulation of Cannabinoid CB1 and Dopamine D2 Receptors Augments cAMP Accumulation in Striatal Neurons: Evidence for a GsLinkage to the CB1 Receptor
1997
Preparation of iodine-123 labeled AM251: A potential SPECT radioligand for the brain cannabinoid CB1 receptor
1996
ENDOCANNABINOID-MEDIATED SYNAPTIC PLASTICITY IN THE CNS
2006
Evidence for an Interaction between CB1 Cannabinoid and Melanocortin MCR-4 Receptors in Regulating Food Intake
2004
Neuronal Diversity and Temporal Dynamics: The Unity of Hippocampal Circuit Operations
2008 StandoutScience
Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
1999
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Cannabinoid Receptor Modulation of Synapses Received by Cerebellar Purkinje Cells
2000
Nabilone increases choreatic movements in Huntington's disease
1999
Absence of Δ-9-Tetrahydrocannabinol Dysphoric Effects in Dynorphin-Deficient Mice
2001
A beneficial aspect of a CB1 cannabinoid receptor antagonist: SR141716A is a potent inhibitor of macrophage infection by the intracellular pathogen Brucella suis
2000
Cannabinoid CB2Receptors and Fatty Acid Amide Hydrolase Are Selectively Overexpressed in Neuritic Plaque-Associated Glia in Alzheimer's Disease Brains
2003
The Endocannabinoid System and the Brain
2012
Characterization of the acute endocrine actions of (−)-11-hydroxy-Δ8-tetrahydrocannabinol-dimethylheptyl (HU-210), a potent synthetic cannabinoid in rats
1998
Reversing cerebellar long-term depression
2003 StandoutNobel
Cannabinoids reduce symptoms of Tourette’s syndrome
2003
Anandamide, a Natural Ligand for the Peripheral Cannabinoid Receptor Is a Novel Synergistic Growth Factor for Hematopoietic Cells
1997
Pharmacological and therapeutic targets for Δ9 tetrahydrocannabinol and cannabidiol
2004
Peripheral cannabinoid receptor, CB2, regulates bone mass
2006
Cannabinoid antagonist SR-141716 inhibits endotoxic hypotension by a cardiac mechanism not involving CB1 or CB2 receptors
2004
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
1999
A role for endocannabinoids in the generation of parkinsonism and levodopa‐induced dyskinesia in MPTP‐lesioned non‐human primate models of Parkinson's disease
2005
Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide.
1995
Mechanism of action of cannabinoids: how it may lead to treatment of cachexia, emesis, and pain.
2006
Mechanisms of Cannabinoid-Receptor–Mediated Inhibition of Synaptic Transmission in Cultured Hippocampal Pyramidal Neurons
1999
Effects of intrastriatal cannabinoids on rotational behavior in rats: Interactions with the dopaminergic system
1998
Molecular cloning of a human cannabinoid receptor which is also expressed in testis
1991
Cannabinoid agonists stimulate both receptor- and non-receptor-mediated signal transduction pathways in cells transfected with and expressing cannabinoid receptor clones.
1992
Hypoactivity of the Spinal Cannabinoid System Results in NMDA-Dependent Hyperalgesia
1998
Expression of Leptin Receptor Isoforms in Rat Brain Microvessels
1998
Effects of cannabinoids on prefrontal neuronal responses to ventral tegmental area stimulation
2001
The effect of δ-9-tetrahydrocannabinol on forebrain ischemia in rat
2000
Endocannabinoids and Food Intake: Newborn Suckling and Appetite Regulation in Adulthood
2005
Cardiovascular Effects of Anandamide in Anesthetized and Conscious Normotensive and Hypertensive Rats
1997
Multiple Functions of Endocannabinoid Signaling in the Brain
2012
Mutation of a Highly Conserved Aspartate Residue in the Second Transmembrane Domain of the Cannabinoid Receptors, CB1 and CB2, Disrupts G-Protein Coupling
1998
Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes.
1994
Works of A B Lynn being referenced
Localization of cannabinoid receptors and nonsaturable high-density cannabinoid binding sites in peripheral tissues of the rat: implications for receptor-mediated immune modulation by cannabinoids.
1994
Systemic interleukin-1 induces early and late patterns of c-fos mRNA expression in brain
1994
Neuronal localization of cannabinoid receptors and second messengers in mutant mouse cerebellum
1991
Cannabinoid receptor localization in brain.
1990 Standout
Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study
1991 Standout