Citation Impact
Citing Papers
The biosynthesis of mammalian melanin.
1982
Human tyrosinase gene, mapped to chromosome 11 (q14 → q21), defines second region of homology with mouse chromosome 7
1988 Nobel
Polyamines in the gut lumen: bioavailability and biodistribution
2001
Tyrosine hydroxylase isoenzyme I is present in human melanosomes: a possible novel function in pigmentation
2003
Are L-tyrosine and L-dopa hormone-like bioregulators?
1990
Protein Kinase C-β Activates Tyrosinase by Phosphorylating Serine Residues in Its Cytoplasmic Domain
1999
UVB-Induced Melanogenesis May Be Mediated Through the MSH-Receptor System.
1989
Rac and Rho: The Story Behind Melanocyte Dendrite Formation
2002
Mislocalization of Melanosomal Proteins in Melanocytes from Mice with Oculocutaneous Albinism Type 2
2001
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Receptors for .beta.-melanocyte-stimulating hormone exhibit positive cooperativity in synchronized melanoma cells
1988
Coexpression of Wild-Type Tyrosinase Enhances Maturation of Temperature-Sensitive Tyrosinase Mutants
2002
BRAFE600-associated senescence-like cell cycle arrest of human naevi
2005 StandoutNature
Alpha tocopheryl succinate inhibits melanocyte‐stimulating hormone (MSH)‐sensitive adenylate cyclase activity in melanoma cells
1987
Dermal dendritic melanocytic proliferations: an update
2004
Inhibition of the Mitogen-activated Protein Kinase Pathway Triggers B16 Melanoma Cell Differentiation
1998
Sorting and Targeting of Melanosomal Membrane Proteins: Signals, Pathways, and Mechanisms
2000
Proper Folding and Endoplasmic Reticulum to Golgi Transport of Tyrosinase Are Induced by Its Substrates, DOPA and Tyrosine
2001
Protein glycosylation
1993
Melanocortins and their implication in melanoma
1995
Regulation of Tyrosinase Expression and Activity in Human Melanoma Cells via Histamine Receptors
1991
Differential Expression and Activity of Melanogenesis-Related Proteins During Induced Hair Growth in Mice
1991
The Discovery of the Melanotropins: A History of Pituitary Endocrinologya
1993
Human Melanocytes as a Target Tissue for Hormones: In Vitro Studies with 1α-25, dihydroxyvitamin D3, α-melanocyte Stimulating Hormone, and Beta-estradiol
1988
Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA
1992
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
2008 StandoutNature
Induction of tyrosinase in human melanoma cells by l-tyrosine phosphate and cytochalasin D
1992
Regulation of mammalian melanogenesis by tyrosinase inhibition
1989
Hormonal stimulation of tyrosinase activity in human foreskin organ cultures
1990
Copper Protein Structures
1991
Growth Regulatory Proteins that Repress Differentiation Markers in Melanocytes Also Downregulate the Transcription Factor Microphthalmia
1996
Melanogenesis During the Anagen-Catagen-Telogen Transformation of the Murine Hair Cycle
1994
The Relationship Between Tyrosinase Activity and Skin Color in Human Foreskins
1990
The Importance of l-Phenylalanine Transport and Its Autocrine Turnover to l-Tyrosine for Melanogenesis in Human Epidermal Melanocytes
1999
Human Melanogenesis is Stimulated by Diacylglycerol
1989
Inhibition of the Phosphatidylinositol 3-Kinase/p70S6-Kinase Pathway Induces B16 Melanoma Cell Differentiation
1996
Different susceptibilities of melanoma cells to retinoic acid-induced changes in melanotic expression
1988
Interactions between ultraviolet light and interleukin-1 on MSH binding in both mouse melanoma and human squamous carcinoma cells
1991
Structural/functional relationships between internal and external MSH receptors: Modulation of expression in Cloudman melanoma cells by UVB radiation
1991
Interferons modulate the expression of hormone receptors on the surface of murine melanoma cells.
1989
L-tyrosine induces tyrosinase expression via a posttranscriptional mechanism
1991
The natural history of a family of transplantable melanomas in hamsters
1988
Effect of Pituitary and Ovarian Hormones on Human Melanocytes In Vitro
1996
Vitamin D, its Precursors, and Metabolites do not Affect Melanization of Cultured Human Melanocytes
1988
UV Light and MSH Receptors
1999
Ultraviolet B and Melanocyte-Stimulating Hormone (MSH) Stimulate mRNA Production for ∝MSH Receptors and Proopiomelanocortin-Derived Peptides in Mouse Melanoma Cells and Transformed Keratinocytes
1995
Abnormal Acidification of Melanoma Cells Induces Tyrosinase Retention in the Early Secretory Pathway
2002
Biology of hypopigmentation
1988
Structure at 2.8 Å resolution of cytochrome c oxidase from Paracoccus denitrificans
1995 StandoutNatureNobel
Stimulation of the receptor for melanocyte‐stimulating hormone by retinoic acid
1990
Activation of melanoma tyrosinase by a cyclic AMP-dependent protein kinase in a cell-free system
1977 Nature
The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins
1985 StandoutScienceNobel
Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes.
1988
Coated pits, coated vesicles, and receptor-mediated endocytosis
1979 StandoutNatureNobel
Evidence suggesting that a cyclic AMP‐dependent protein kinase is a positive regulator of proliferation in Cloudman S91 melanoma cells
1979
Immunologic cross-reactivity of the low density lipoprotein receptor from bovine adrenal cortex, human fibroblasts, canine liver and adrenal gland, and rat liver.
1981 StandoutNobel
Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides.
1995
LDL receptors in coated vesicles isolated from bovine adrenal cortex: Binding sites unmasked by detergent treatment
1980 StandoutNobel
MSH inhibits growth in a line of amelanotic hamster melanoma cells and induces increases in cyclic AMP levels and tyrosinase activity without inducing melanogenesis
1989
A Strategy for the Chemoselective Synthesis of O-Linked Glycopeptides with Native Sugar−Peptide Linkages
1997 StandoutNobel
Signalling mechanisms of endothelin-induced mitogenesis and melanogenesis in human melanocytes
1996
Isolation and sequence of a cDNA clone for human tyrosinase that maps at the mouse c-albino locus.
1987
A role for clathrin light chains in the recognition of clathrin cages by ‘uncoating ATPase’
1984 StandoutNatureNobel
Visualization of lipoprotein receptors by ligand blotting.
1983 StandoutNobel
A domain of clathrin that forms coats.
1982 StandoutNobel
Combinatorial diffusion assay used to identify topically active melanocyte-stimulating hormone receptor antagonists.
1995
Hormone receptor topology and dynamics: Morphological analysis using ferritin-labeled epidermal growth factor
1979 StandoutNobel
A genetical model for vitiligo.
1988
Effect of Alpha- and Beta-Melanocyte Stimulating Hormones on the Skin Colour of Man
1961 Nature
Melanocyte-stimulating hormone promotes activation of pre-existing tyrosinase molecules in Cloudman S91 melanoma cells
1975 Nature
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
New regulators of melanin biosynthesis and the autodestruction of melanoma cells
1980 Nature
Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells
1976 StandoutNatureNobel
Targeted killing of cultured cells by receptor-dependent photosensitization.
1981 StandoutNobel
The role of hormone receptors and GTP-regulatory proteins in membrane transduction
1980 StandoutNatureNobel
L-Tyrosine stimulates induction of tyrosinase activity by MSH and reduces cooperative interactions between MSH receptors in hamster melanoma cells
1989
Regulation of Melanogenesis in Melanocytes
1988
Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells
1997
Genes and pathways downstream of telomerase in melanoma metastasis
2006 StandoutNobel
Hypothesis: Possible Role for the Melatonin Receptor in Vitiligo: Discussion Paper
1989
The number of receptors for beta-melanocyte stimulating hormone in Cloudman melanoma cells is increased by dibutyryl adenosine 3':5'-cyclic monophosphate or cholera toxin.
1977
Regulation of Plasma Cholesterol by Lipoprotein Receptors
1981 StandoutScienceNobel
The LDL receptor locus in familial hypercholesterolemia: Multiple mutations disrupt transport and processing of a membrane receptor
1983 StandoutNobel
Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain
1985 StandoutNobel
A transmembrane precursor of secretory component. The receptor for transcellular transport of polymeric immunoglobulins.
1982 StandoutNobel
W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity
1995 StandoutNature
A Receptor-Mediated Pathway for Cholesterol Homeostasis
1986 StandoutScienceNobel
Different cis-Acting Elements Are Involved in the Regulation of TRP1 and TRP2 Promoter Activities by Cyclic AMP: Pivotal Role of M Boxes (GTCATGTGCT) and of Microphthalmia
1998
Insulin receptors in normal and transformed fibroblasts: relationship to growth and transformation
1976
A cell-specific enhancer far upstream of the mouse tyrosinase gene confers high level and copy number-related expression in transgenic mice.
1994
Novel Proteinaceous Infectious Particles Cause Scrapie
1982 StandoutScienceNobel
Spermidine in health and disease
2018 StandoutScience
Phenylalanine hydroxylase in melanoma cells
1978
Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model
1998 StandoutScience
Fluorescent labeling of hormone receptors in viable cells: preparation and properties of highly fluorescent derivatives of epidermal growth factor and insulin.
1978
A new enzymatic function in the melanogenic pathway. The 5,6-dihydroxyindole-2-carboxylic acid oxidase activity of tyrosinase-related protein-1 (TRP1).
1994
Cytotoxic analogs of luteinizing hormone-releasing hormone containing doxorubicin or 2-pyrrolinodoxorubicin, a derivative 500-1000 times more potent.
1996 Nobel
Role of the Melanocyte in Epidermal Inflammatory and Immune Responses
1988
Interleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion protein.
1988
Endoplasmic reticulum retention is a common defect associated with tyrosinase-negative albinism
2000
Functional integrity of desensitized beta-adrenergic receptors.
1983 StandoutNobel
Modulation of growth in normal and malignant melanocytic cells by all‐trans retinoic acid
1992
Positive regulation of melanin pigmentation by two key substrates of the melanogenic pathway, l-tyrosine and l-dopa
1988
Solubilization of the low density lipoprotein receptor
1979 StandoutNobel
The effects of pro-opiomelanocortin peptides on cyclic AMP and tyrosinase in melanoma cells
1986
Genetic Dissection of Complex Traits
1994 StandoutScience
Enzymatic control of pigmentation in mammals
1991
Studies on the Cloudman melanoma cell line as a model for the action of MSH.
1986
Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts
1981 StandoutNobel
Growth Factors and Cancer
1991 StandoutScience
Microinjection of a protein-tyrosine-phosphatase inhibits insulin action in Xenopus oocytes.
1990 StandoutNobel
Posttranslational processing of the LDL receptor and its genetic disruption in familial hypercholesterolemia
1982 StandoutNobel
Transfer Mechanism Of Melanosomes In Epidermal Cell Culture
1976
Melanoma cells which require cyclic AMP for growth
1975 Nature
The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA
1984 StandoutNobel
cDNA cloning of the bovine low density lipoprotein receptor: feedback regulation of a receptor mRNA.
1983 StandoutNobel
Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein
1997 StandoutScience
Fmoc-Based Synthesis of Peptide-αThioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation
1999 StandoutNobel
EXTRAPIGMENTARY EFFECTS OF MELANOCYTE-STIMULATING HORMONE IN AMENORRHŒIC WOMEN
1968 StandoutNobel
Mutation in LDL Receptor: Alu-Alu Recombination Deletes Exons Encoding Transmembrane and Cytoplasmic Domains
1985 StandoutScienceNobel
Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme
1985 StandoutNobel
Enzymatic recycling of clathrin from coated vesicles
1986 StandoutNobel
Effect of testosterone on imidazole-induced tyrosinase expression in B16 melanoma cell culture.
1988
UVB-Induced melanogenesis may be mediated through the MSH-receptor system
1989
Modulation of melanocyte-stimulating hormone receptor expression on normal human melanocytes: evidence for a regulatory role of ultraviolet B, interleukin-1α, interleukin-1β, endothelin-1 and tumour necrosis factor-α
1998
Polypeptide Hormones: Intracellular Receptors and Internalization
1981
Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts
1983 StandoutNobel
Epidermal Growth Factor
1979 StandoutNobel
Domain map of the LDL receptor: Sequence homology with the epidermal growth factor precursor
1984 StandoutNobel
A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.
1982 StandoutNobel
Inhibition of Rho Is Required for cAMP-induced Melanoma Cell Differentiation
1998
Tolerance, the thymus, and suppressor T cells.
1977
Factors Regulating Growth And Pigmentation Of Melanoma Cells
1976
A Test of Clathrin Function in Protein Secretion and Cell Growth
1985 StandoutScienceNobel
pH and the recycling of transferrin during receptor-mediated endocytosis.
1983 StandoutNobel
α-melanocyte stimulating hormone and its analogue nle4dphe7α-MSH affect morphology, tyrosinase activity and melanogenesis in cultured human melanocytes
1994
Cassette of Eight Exons Shared by Genes for LDL Receptor and EGF Precursor
1985 StandoutScienceNobel
Human melanocyte senescence and melanoma susceptibility genes
2003
Epidermal growth factor: Biological activity requires persistent occupation of high-affinity cell surface receptors
1978
Corticotropin Releasing Hormone and Proopiomelanocortin Involvement in the Cutaneous Response to Stress
2000
Alpha-melanocyte-stimulating hormone regulation of tyrosinase in Cloudman S-91 mouse melanoma cell cultures.
1987
Presence of epidermal growth factor receptors and influence of epidermal growth factor on proliferation and aging in cultured smooth muscle cells
1979
Interleukin-2: Inception, Impact, and Implications
1988 StandoutScience
Works of A B Lerner being referenced
Ultrastructure and cell biology of pigment cells. Intracellular dynamics and the fine structure of melanocytes with special reference to the effects of MSH and cyclic AMP on microtubules and 10-nm filaments.
1973
Tyrosinase and inhibition of proliferation of melanoma cells and fibroblasts
1977
Morphology of melanocytes in hair bulbs and eyes of vitiligo mice.
1987
Tyrosinases of murine melanocytes with mutations at the albino locus.
1988
Regulation of Melanocyte Stimulating Hormone Action at the Receptor Level: Discontinuous Binding of Hormone to Synchronized Mouse Melanoma Cells During the Cell Cycle
1974
S-adenosylmethionine decarboxylase activity and utilization of exogenous putrescine are enhanced in colon cancer cells stimulated to grow by EGF.
1998
Assay of Melanotropic Peptides in an in Vitro Mammalian System
1981
Iodination of beta-melanotropin. Time course analysis of reaction mixtures by high pressure liquid chromatography and characterization of biologically active mono- and diiodo-beta-melanotropin.
1982
Regulation of tyrosinase in human melanocytes grown in culture.
1983
The dual effect of melanocyte-stimulating hormone (MSH) on the growth of cultured mouse melanoma cells
1977
Melanotropin–daunomycin conjugate shows receptor-mediated cytotoxicity in cultured murine melanoma cells
1977 Nature
Vitiligo and disorders of the retinal pigment epithelium.
1983
Vitiligo.
1959
Hormonal Control of Pigmentation
1960
Association of cell surface receptors for melanotropin with the Golgi region in mouse melanoma cells.
1976
Melanomas in horses.
1973
Melanoma cells resistant to inhibition of growth by melanocyte stimulating hormone.
1975
The dual effect of melanocyte-stimulating hormone (MSH) on the growth of cultured mouse melanoma cells
1977